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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 22

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Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.
Patra A, Zhang Q, Guengerich FP, Egli M
(2016) J Biol Chem 291: 24304-24313
MeSH Terms: Bacterial Proteins, Crystallography, X-Ray, DNA, DNA Polymerase beta, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Humans, Sulfolobus solfataricus, Thymine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Chang SC, Fedeles BI, Wu J, Delaney JC, Li D, Zhao L, Christov PP, Yau E, Singh V, Jost M, Drennan CL, Marnett LJ, Rizzo CJ, Levine SS, Guengerich FP, Essigmann JM
(2015) Nucleic Acids Res 43: 5489-500
MeSH Terms: DNA Adducts, DNA Damage, DNA Polymerase beta, DNA Repair, DNA Repair Enzymes, Dioxygenases, Guanine, High-Throughput Nucleotide Sequencing, Mutagenesis, Mutation, Sequence Analysis, DNA, Sequence Deletion
Added January 7, 2016
0 Communities
3 Members
0 Resources
12 MeSH Terms
Incorporation of nucleoside probes opposite O⁶-methylguanine by Sulfolobus solfataricus DNA polymerase Dpo4: importance of hydrogen bonding.
Stornetta A, Angelov T, Guengerich FP, Sturla SJ
(2013) Chembiochem 14: 1634-9
MeSH Terms: DNA Polymerase beta, Fluorescent Dyes, Guanine, Hydrogen Bonding, Molecular Structure, Nucleosides, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.
Shanmugam G, Minko IG, Banerjee S, Christov PP, Kozekov ID, Rizzo CJ, Lloyd RS, Egli M, Stone MP
(2013) Chem Res Toxicol 26: 1348-60
MeSH Terms: Crystallography, X-Ray, DNA Adducts, DNA Polymerase beta, Deoxyguanosine, Models, Molecular, Molecular Structure, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
7 MeSH Terms
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.
Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP
(2012) J Biol Chem 287: 35516-35526
MeSH Terms: Cell-Free System, DNA Adducts, DNA Polymerase beta, DNA-Directed DNA Polymerase, Guanine, Humans, Nuclear Proteins, Nucleotidyltransferases
Added March 7, 2014
0 Communities
3 Members
0 Resources
8 MeSH Terms
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.
Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP
(2012) Chem Res Toxicol 25: 422-35
MeSH Terms: Aldehydes, Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, Deoxyguanosine, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
7 MeSH Terms
Bypass of aflatoxin B1 adducts by the Sulfolobus solfataricus DNA polymerase IV.
Banerjee S, Brown KL, Egli M, Stone MP
(2011) J Am Chem Soc 133: 12556-68
MeSH Terms: Aflatoxin B1, Crystallography, X-Ray, DNA Adducts, DNA Polymerase beta, Models, Molecular, Mutation, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
7 MeSH Terms
Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins in DNA replication.
Choi JY, Eoff RL, Pence MG, Wang J, Martin MV, Kim EJ, Folkmann LM, Guengerich FP
(2011) J Biol Chem 286: 31180-93
MeSH Terms: Bacterial Proteins, DNA, DNA Damage, DNA Polymerase I, DNA Polymerase II, DNA Polymerase III, DNA Polymerase beta, DNA Replication, DNA-Directed DNA Polymerase, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine.
Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP
(2011) Chem Res Toxicol 24: 1071-9
MeSH Terms: Base Pair Mismatch, DNA Polymerase I, DNA Polymerase II, DNA Polymerase beta, Deoxyadenosines, Escherichia coli, Hydrogen Bonding, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Oligodeoxyribonucleotides, Protons, Sulfolobus solfataricus, Transition Temperature
Added March 7, 2014
0 Communities
3 Members
0 Resources
13 MeSH Terms
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota.
Pence MG, Choi JY, Egli M, Guengerich FP
(2010) J Biol Chem 285: 40666-72
MeSH Terms: Bacterial Proteins, Base Pairing, Catalytic Domain, DNA, DNA Polymerase I, DNA Polymerase beta, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Geobacillus stearothermophilus, Guanine, Humans, Hydrogen Bonding, Kinetics, Structure-Activity Relationship, Sulfolobus, Thymine Nucleotides
Added March 7, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms