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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer.
Leichman L, Groshen S, O'Neil BH, Messersmith W, Berlin J, Chan E, Leichman CG, Cohen SJ, Cohen D, Lenz HJ, Gold P, Boman B, Fielding A, Locker G, Cason RC, Hamilton SR, Hochster HS
(2016) Oncologist 21: 172-7
MeSH Terms: Adult, Aged, Colorectal Neoplasms, DNA Methylation, DNA Mismatch Repair, Disease-Free Survival, Female, Humans, Male, Microsatellite Instability, Middle Aged, Phthalazines, Piperazines, Poly(ADP-ribose) Polymerase Inhibitors
Added May 7, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Proteogenomic analysis reveals unanticipated adaptations of colorectal tumor cells to deficiencies in DNA mismatch repair.
Halvey PJ, Wang X, Wang J, Bhat AA, Dhawan P, Li M, Zhang B, Liebler DC, Slebos RJ
(2014) Cancer Res 74: 387-97
MeSH Terms: Cell Growth Processes, Cell Line, Tumor, Colorectal Neoplasms, DNA Mismatch Repair, Humans, Proteomics, Sequence Analysis, Protein
Added March 7, 2014
0 Communities
4 Members
0 Resources
7 MeSH Terms
Distinct molecular features of colorectal cancer in Ghana.
Raskin L, Dakubo JC, Palaski N, Greenson JK, Gruber SB
(2013) Cancer Epidemiol 37: 556-61
MeSH Terms: African Americans, Colorectal Neoplasms, DNA Mismatch Repair, DNA, Neoplasm, Exons, Female, Genes, ras, Ghana, Humans, Immunohistochemistry, Male, Microsatellite Instability, Middle Aged, Molecular Epidemiology, Paraffin Embedding, Proto-Oncogene Proteins B-raf
Added March 7, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
TagRecon: high-throughput mutation identification through sequence tagging.
Dasari S, Chambers MC, Slebos RJ, Zimmerman LJ, Ham AJ, Tabb DL
(2010) J Proteome Res 9: 1716-26
MeSH Terms: Algorithms, Cell Line, Tumor, Chromatography, Liquid, Colonic Neoplasms, Computational Biology, DNA Mismatch Repair, Data Mining, Databases, Protein, Extracellular Matrix, Humans, Hydroxyproline, Models, Genetic, Mutation, Peptide Fragments, Peptide Mapping, Sequence Tagged Sites, Tandem Mass Spectrometry, Yeasts
Added March 5, 2014
0 Communities
4 Members
0 Resources
18 MeSH Terms
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB
(2009) Clin Cancer Res 15: 2829-39
MeSH Terms: Algorithms, Antineoplastic Agents, Benzoquinones, Cell Cycle, Cell Line, Tumor, Chromones, Colorectal Neoplasms, Computational Biology, DNA Mismatch Repair, Drug Evaluation, Preclinical, Enzyme Inhibitors, Gene Expression Profiling, Humans, Hydroxamic Acids, Immunosuppressive Agents, Lactams, Macrocyclic, Microsatellite Instability, Morpholines, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Sirolimus
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Pediatric duodenal cancer and biallelic mismatch repair gene mutations.
Roy S, Raskin L, Raymond VM, Thibodeau SN, Mody RJ, Gruber SB
(2009) Pediatr Blood Cancer 53: 116-20
MeSH Terms: Adaptor Proteins, Signal Transducing, Adenocarcinoma, Adenosine Triphosphatases, Adolescent, Antineoplastic Combined Chemotherapy Protocols, Chemotherapy, Adjuvant, Consanguinity, DNA Mismatch Repair, DNA Repair Enzymes, DNA-Binding Proteins, Duodenal Neoplasms, Female, Germ-Line Mutation, Humans, Lymphatic Metastasis, Male, Mismatch Repair Endonuclease PMS2, MutL Protein Homolog 1, MutS Homolog 2 Protein, Nuclear Proteins, Pancreatic Neoplasms, Pedigree, Radiotherapy, Adjuvant
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms