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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 28

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M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product.
Garcia RC, Dati LM, Torres LH, da Silva MA, Udo MS, Abdalla FM, da Costa JL, Gorj√£o R, Afeche SC, Yonamine M, Niswender CM, Conn PJ, Camarini R, Sandoval MR, Marcourakis T
(2015) Sci Rep 5: 17555
MeSH Terms: Animals, Apoptosis, CHO Cells, Cocaine, Cricetinae, Cricetulus, DNA Fragmentation, Female, Hippocampus, Neurotoxicity Syndromes, Neurotoxins, Rats, Receptor, Muscarinic M1, Receptor, Muscarinic M3, Time Factors
Added February 18, 2016
0 Communities
2 Members
0 Resources
15 MeSH Terms
The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling.
Sethman CR, Hawiger J
(2013) PLoS One 8: e70994
MeSH Terms: Apoptosis, Armadillo Domain Proteins, Caspase 6, Cell Line, Cell Nucleus, Cytoskeletal Proteins, DNA Fragmentation, Gene Expression, Gene Order, Genetic Vectors, Humans, Immunity, Innate, Lamins, Protein Stability, Protein Transport, Signal Transduction, Tumor Necrosis Factor-alpha
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Age-related susceptibility to apoptosis in human retinal pigment epithelial cells is triggered by disruption of p53-Mdm2 association.
Bhattacharya S, Chaum E, Johnson DA, Johnson LR
(2012) Invest Ophthalmol Vis Sci 53: 8350-66
MeSH Terms: Acetylation, Adult, Aged, Aged, 80 and over, Aging, Apoptosis, Apoptosis Regulatory Proteins, Benzamides, Blotting, Western, Caspase 3, Cell Proliferation, Cells, Cultured, DNA Fragmentation, Disease Susceptibility, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Indirect, Humans, Imidazoles, In Situ Nick-End Labeling, Middle Aged, Naphthols, Phosphorylation, Piperazines, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, RNA, Small Interfering, Retinal Pigment Epithelium, Sirtuin 1, Sirtuin 2, Tumor Suppressor Protein p53
Added June 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Inhibition of Mdm2 sensitizes human retinal pigment epithelial cells to apoptosis.
Bhattacharya S, Ray RM, Chaum E, Johnson DA, Johnson LR
(2011) Invest Ophthalmol Vis Sci 52: 3368-80
MeSH Terms: Adult, Apoptosis, Blotting, Western, Caspase 3, Caspase 9, Cell Line, Cell Proliferation, DNA Fragmentation, Humans, Imidazoles, Piperazines, Protein Binding, Proto-Oncogene Proteins c-bcl-2, Proto-Oncogene Proteins c-mdm2, RNA, Small Interfering, Retinal Pigment Epithelium, Transfection, Tumor Suppressor Protein p53, bcl-X Protein
Added June 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation.
Li Y, Yokota T, Gama V, Yoshida T, Gomez JA, Ishikawa K, Sasaguri H, Cohen HY, Sinclair DA, Mizusawa H, Matsuyama S
(2007) Cell Death Differ 14: 2058-67
MeSH Terms: Acetylation, Animals, Antigens, Nuclear, Caspases, Cell Death, Cell Line, Cyclic AMP Response Element-Binding Protein, Cytoprotection, DNA Fragmentation, DNA-Binding Proteins, Histone Acetyltransferases, Humans, Ku Autoantigen, Mutant Proteins, Peptides, Protein Binding, Protein Conformation, Rats, Rats, Sprague-Dawley, Resveratrol, Stilbenes, Vacuoles, bcl-2-Associated X Protein
Added October 26, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure.
Aravindan N, Aravindan S, Riedel BJ, Weng HR, Shaw AD
(2007) Ren Fail 29: 399-407
MeSH Terms: Acute Kidney Injury, Animals, Apoptosis, DNA Fragmentation, Disease Models, Animal, Diuretics, Furosemide, Male, Oligonucleotide Array Sequence Analysis, Proto-Oncogene Proteins c-akt, Rats, Rats, Sprague-Dawley, Reperfusion Injury
Added October 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Effects of isoflurane, pentobarbital, and urethane on apoptosis and apoptotic signal transduction in rat kidney.
Aravindan N, Cata JP, Hoffman L, Dougherty PM, Riedel BJ, Price KJ, Shaw AD
(2006) Acta Anaesthesiol Scand 50: 1229-37
MeSH Terms: Animals, Apoptosis, DNA Fragmentation, DNA Primers, Isoflurane, Kidney, Male, Oligonucleotide Array Sequence Analysis, Pentobarbital, Rats, Rats, Sprague-Dawley, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Urethane, bcl-2-Associated X Protein
Added October 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Effect of fenoldopam on ischemia/reperfusion-induced apoptosis.
Aravindan N, Cata JP, Dougherty PM, Shaw AD
(2006) Ren Fail 28: 337-44
MeSH Terms: Analysis of Variance, Animals, Antihypertensive Agents, Apoptosis, DNA Fragmentation, Fenoldopam, Kidney, Male, Models, Animal, Oligonucleotide Array Sequence Analysis, Random Allocation, Rats, Rats, Sprague-Dawley, Reperfusion Injury, Transcription, Genetic
Added October 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.
Huang W, Zhang J, Washington M, Liu J, Parant JM, Lozano G, Moore DD
(2005) Mol Endocrinol 19: 1646-53
MeSH Terms: Animals, Apoptosis, Cell Proliferation, Chromatin Immunoprecipitation, Constitutive Androstane Receptor, DNA, DNA Fragmentation, Flow Cytometry, HeLa Cells, Hepatocytes, Hepatomegaly, Humans, Liver, Liver Neoplasms, Mice, Mice, Transgenic, Nuclear Proteins, Protein Binding, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, RNA, Receptors, Cytoplasmic and Nuclear, Time Factors, Transcription Factors, Transfection, Tumor Suppressor Protein p53, Up-Regulation, Xenobiotics
Added March 5, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1.
West JD, Ji C, Marnett LJ
(2005) J Biol Chem 280: 15141-7
MeSH Terms: Animals, Apoptosis, Blotting, Western, Caspase 3, Caspase 7, Caspases, Cell Line, Cell Line, Tumor, DNA Fragmentation, DNA Repair, Deoxyribonucleases, Enzyme Activation, Epitopes, Genetic Vectors, Glycoside Hydrolases, Humans, Immunoprecipitation, Lipid Peroxidation, Mice, Models, Biological, Models, Molecular, Plasmids, Poly Adenosine Diphosphate Ribose, Poly(ADP-ribose) Polymerases, Poly-ADP-Ribose Binding Proteins, Protein Binding, Time Factors, Transcription, Genetic, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms