Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 190

Publication Record

Connections

The abundant DNA adduct -methyl deoxyguanosine contributes to miscoding during replication by human DNA polymerase η.
Njuma OJ, Su Y, Guengerich FP
(2019) J Biol Chem 294: 10253-10265
MeSH Terms: DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Humans, Molecular Structure
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.
Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ
(2018) Nucleic Acids Res 46: 3458-3467
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, DNA Adducts, DNA, Mitochondrial, Electron Transport, Endothelial Cells, Gene Expression Regulation, Humans, Hypertension, Pulmonary, Lipid Peroxidation, Mice, Mice, Transgenic, Mitochondria, Mutagenesis, Oxidants, Oxidative Stress, Purine Nucleosides, Reactive Oxygen Species, Superoxides
Added March 14, 2018
0 Communities
3 Members
0 Resources
19 MeSH Terms
Selective base excision repair of DNA damage by the non-base-flipping DNA glycosylase AlkC.
Shi R, Mullins EA, Shen XX, Lay KT, Yuen PK, David SS, Rokas A, Eichman BF
(2018) EMBO J 37: 63-74
MeSH Terms: Adenine, Alkylation, Amino Acid Sequence, Bacillus cereus, Catalytic Domain, Crystallography, X-Ray, DNA Adducts, DNA Damage, DNA Glycosylases, DNA Repair, Models, Molecular, Protein Conformation, Sequence Homology
Added March 21, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Mullins EA, Shi R, Eichman BF
(2017) Nat Chem Biol 13: 1002-1008
MeSH Terms: Biological Products, DNA Adducts, DNA Damage, DNA Repair, Drug Resistance, Bacterial, Duocarmycins, Indoles, Molecular Structure, Pyrroles
Added August 26, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
Formation of S-[2-(N-Deoxyadenosinyl)ethyl]glutathione in DNA and Replication Past the Adduct by Translesion DNA Polymerases.
Sedgeman CA, Su Y, Guengerich FP
(2017) Chem Res Toxicol 30: 1188-1196
MeSH Terms: Animals, Cattle, Chromatography, Liquid, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Ethylene Dibromide, Glutathione, Tandem Mass Spectrometry
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases.
Wickramaratne S, Ji S, Mukherjee S, Su Y, Pence MG, Lior-Hoffmann L, Fu I, Broyde S, Guengerich FP, Distefano M, Schärer OD, Sham YY, Tretyakova N
(2016) J Biol Chem 291: 23589-23603
MeSH Terms: Amination, Amino Acid Sequence, Base Sequence, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Guanine, Humans, Molecular Dynamics Simulation, Oxidation-Reduction, Peptides, Proteins, Recombinant Proteins
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Mechanisms of mutagenesis: DNA replication in the presence of DNA damage.
Liu B, Xue Q, Tang Y, Cao J, Guengerich FP, Zhang H
(2016) Mutat Res Rev Mutat Res 768: 53-67
MeSH Terms: Animals, DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Environmental Exposure, Genetic Predisposition to Disease, Humans, Mutagenesis, Mutagens, Mutation, Protein Binding
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η.
Patra A, Su Y, Zhang Q, Johnson KM, Guengerich FP, Egli M
(2016) J Biol Chem 291: 14134-14145
MeSH Terms: Adenosine, Crystallography, X-Ray, DNA Adducts, DNA-Directed DNA Polymerase, Humans, Mass Spectrometry, Protein Structure, Tertiary
Added March 14, 2018
0 Communities
1 Members
0 Resources
7 MeSH Terms
Effects of Twelve Germline Missense Variations on DNA Lesion and G-Quadruplex Bypass Activities of Human DNA Polymerase REV1.
Yeom M, Kim IH, Kim JK, Kang K, Eoff RL, Guengerich FP, Choi JY
(2016) Chem Res Toxicol 29: 367-79
MeSH Terms: DNA, DNA Adducts, DNA Damage, G-Quadruplexes, Germ-Line Mutation, Humans, Models, Molecular, Mutation, Missense, Nuclear Proteins, Nucleotidyltransferases
Added March 14, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Mullins EA, Shi R, Parsons ZD, Yuen PK, David SS, Igarashi Y, Eichman BF
(2015) Nature 527: 254-8
MeSH Terms: Bacillus cereus, Base Pairing, Biocatalysis, Catalytic Domain, Crystallography, X-Ray, DNA Adducts, DNA Damage, DNA Glycosylases, DNA Repair, Duocarmycins, Indoles, Models, Molecular, Pyrroles
Added November 10, 2015
1 Communities
1 Members
0 Resources
13 MeSH Terms