Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR
(2016) Nature 537
: 234-238MeSH Terms: Animals, Antibodies, B-Lymphocytes, Cell Hypoxia, Cell Proliferation, Cell Survival, Cytosine Deaminase, Germinal Center, Hypoxia, Immunoglobulin Class Switching, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred C57BL, Multiprotein Complexes, TOR Serine-Threonine KinasesAdded August 9, 2016
15 MeSH Terms
Genetic analysis of the localization of APOBEC3F to human immunodeficiency virus type 1 virion cores.
Donahue JP, Levinson RT, Sheehan JH, Sutton L, Taylor HE, Meiler J, D'Aquila RT, Song C
(2015) J Virol 89
: 2415-24MeSH Terms: Cell Line, Cytosine Deaminase, DNA Mutational Analysis, Genes, Reporter, HIV-1, Humans, Luciferases, Models, Molecular, Mutagenesis, Site-Directed, Mutation, Missense, Staining and Labeling, Virus Assembly, beta-GalactosidaseAdded January 24, 2015
13 MeSH Terms
APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry.
Xuan D, Li G, Cai Q, Deming-Halverson S, Shrubsole MJ, Shu XO, Kelley MC, Zheng W, Long J
(2013) Carcinogenesis 34
: 2240-3MeSH Terms: Adult, Aged, Breast Neoplasms, Case-Control Studies, Cytidine Deaminase, Cytosine Deaminase, European Continental Ancestry Group, Female, Gene Deletion, Genetic Predisposition to Disease, Humans, Middle Aged, Odds Ratio, Polymorphism, Genetic, Risk Factors, TennesseeAdded December 10, 2013
16 MeSH Terms
A common deletion in the APOBEC3 genes and breast cancer risk.
Long J, Delahanty RJ, Li G, Gao YT, Lu W, Cai Q, Xiang YB, Li C, Ji BT, Zheng Y, Ali S, Shu XO, Zheng W
(2013) J Natl Cancer Inst 105
: 573-9MeSH Terms: Adult, Aged, Asian Continental Ancestry Group, Breast Neoplasms, China, Cytidine Deaminase, Cytosine Deaminase, DNA Copy Number Variations, Female, Gene Deletion, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Middle Aged, Odds Ratio, Real-Time Polymerase Chain Reaction, Risk Assessment, Risk FactorsAdded December 10, 2013
18 MeSH Terms
Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth.
Bowen AL, Tian C, LaFleur BJ, Crowe JE
(2006) Hum Immunol 67
: 43-6MeSH Terms: Adult, B-Lymphocytes, Cytidine Deaminase, Cytosine Deaminase, DNA-Directed DNA Polymerase, Gene Expression Regulation, Enzymologic, Humans, Infant, Newborn, Somatic Hypermutation, Immunoglobulin, Transcription, Genetic, Up-RegulationAdded August 6, 2012
11 MeSH Terms
Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.
Wei J, Blum S, Unger M, Jarmy G, Lamparter M, Geishauser A, Vlastos GA, Chan G, Fischer KD, Rattat D, Debatin KM, Hatzopoulos AK, Beltinger C
(2004) Cancer Cell 5
: 477-88MeSH Terms: Animals, Bone Neoplasms, Bystander Effect, Carcinoma, Lewis Lung, Cell Hypoxia, Cytosine Deaminase, Embryonic and Fetal Development, Endothelium, Vascular, Fluorouracil, Gene Targeting, Genes, Transgenic, Suicide, Genetic Therapy, Genetic Vectors, Injections, Intravenous, Killer Cells, Natural, Lung Neoplasms, Male, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Neovascularization, Pathologic, Osteosarcoma, Pentosyltransferases, Prodrugs, Recombinant Fusion Proteins, Stem Cells, Survival Rate, Uracil, Vascular Endothelial Growth Factor AAdded November 18, 2010
29 MeSH Terms
The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines.
Ge Y, Jensen TL, Stout ML, Flatley RM, Grohar PJ, Ravindranath Y, Matherly LH, Taub JW
(2004) Cancer Res 64
: 728-35MeSH Terms: Base Sequence, Cell Death, Cell Line, Tumor, Cells, Cultured, Cytarabine, Cytosine Deaminase, DNA Primers, DNA-Binding Proteins, Down Syndrome, Erythroid-Specific DNA-Binding Factors, Exons, GATA1 Transcription Factor, Humans, Introns, Leukemia, Molecular Sequence Data, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factors, Transcription, GeneticAdded March 5, 2014
19 MeSH Terms