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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 22

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p53 has a direct apoptogenic role at the mitochondria.
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM
(2003) Mol Cell 11: 577-90
MeSH Terms: Animals, Apoptosis, Cytochrome c Group, DNA, HeLa Cells, Humans, Immunoblotting, In Situ Nick-End Labeling, Mice, Mice, Inbred C57BL, Microsomes, Liver, Mitochondria, Models, Molecular, Mutation, Plasmids, Protein Binding, Protein Structure, Tertiary, Proto-Oncogene Proteins c-bcl-2, Signal Transduction, Structure-Activity Relationship, Transcription, Genetic, Transcriptional Activation, Transfection, Tumor Suppressor Protein p53, bcl-X Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway.
Remondino A, Kwon SH, Communal C, Pimentel DR, Sawyer DB, Singh K, Colucci WS
(2003) Circ Res 92: 136-8
MeSH Terms: Animals, Apoptosis, Bongkrekic Acid, Caspase Inhibitors, Catalase, Cells, Cultured, Cytochrome c Group, Enzyme Inhibitors, Free Radical Scavengers, Ion Channels, JNK Mitogen-Activated Protein Kinases, Metalloporphyrins, Mitochondria, Mitochondrial Membrane Transport Proteins, Mitochondrial Permeability Transition Pore, Mitogen-Activated Protein Kinases, Myocytes, Cardiac, Norepinephrine, Organometallic Compounds, Prazosin, Rats, Reactive Oxygen Species, Receptors, Adrenergic, beta, Salicylates, Signal Transduction
Added March 5, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.
Zou H, Yang R, Hao J, Wang J, Sun C, Fesik SW, Wu JC, Tomaselli KJ, Armstrong RC
(2003) J Biol Chem 278: 8091-8
MeSH Terms: Amino Acid Sequence, Animals, Apoptosis, Apoptotic Protease-Activating Factor 1, Caspase 3, Caspase 9, Caspase Inhibitors, Caspases, Cytochrome c Group, Enzyme Activation, Humans, Hydrolysis, Kinetics, Molecular Sequence Data, Proteins, Recombinant Proteins, Sequence Homology, Amino Acid, X-Linked Inhibitor of Apoptosis Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Function of BID -- a molecule of the bcl-2 family -- in ischemic cell death in the brain.
Plesnila N, Zinkel S, Amin-Hanjani S, Qiu J, Korsmeyer SJ, Moskowitz MA
(2002) Eur Surg Res 34: 37-41
MeSH Terms: Animals, Apoptosis, BH3 Interacting Domain Death Agonist Protein, Brain Ischemia, Carrier Proteins, Cytochrome c Group, Gene Expression, Mice, Mice, Inbred C57BL, Mice, Knockout, Phenotype, Proto-Oncogene Proteins c-bcl-2, Rats
Added June 9, 2010
0 Communities
1 Members
0 Resources
13 MeSH Terms
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.
Armstrong JS, Steinauer KK, Hornung B, Irish JM, Lecane P, Birrell GW, Peehl DM, Knox SJ
(2002) Cell Death Differ 9: 252-63
MeSH Terms: Antimetabolites, Antineoplastic, Apoptosis, Buthionine Sulfoximine, Cell Cycle, Cytochrome c Group, Cytosol, Dithiothreitol, Glutathione, Humans, Lymphoma, B-Cell, Membrane Potentials, Mitochondria, NF-kappa B, Protein Transport, Reactive Oxygen Species, Signal Transduction, Transcription Factor RelA, Tumor Cells, Cultured, Tumor Suppressor Protein p53
Added February 15, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.
Ji C, Amarnath V, Pietenpol JA, Marnett LJ
(2001) Chem Res Toxicol 14: 1090-6
MeSH Terms: Aldehydes, Apoptosis, Caspase 3, Caspases, Colorectal Neoplasms, Cross-Linking Reagents, Cytochrome c Group, DNA Damage, Enzyme Induction, Gene Expression Regulation, Neoplastic, Genes, bcl-2, Humans, Lipid Peroxidation, Mitochondria, Proto-Oncogene Proteins c-bcl-2, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
Yin XM, Wang K, Gross A, Zhao Y, Zinkel S, Klocke B, Roth KA, Korsmeyer SJ
(1999) Nature 400: 886-91
MeSH Terms: Animals, Antigens, CD, Apoptosis, BH3 Interacting Domain Death Agonist Protein, Carrier Proteins, Caspases, Cells, Cultured, Cytochrome c Group, Enzyme Activation, Liver, Male, Membrane Potentials, Mice, Mice, Inbred C57BL, Mitochondria, Proto-Oncogene Proteins, Receptors, Tumor Necrosis Factor, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, fas Receptor
Added September 7, 2011
1 Communities
1 Members
0 Resources
20 MeSH Terms
Determination of rate constants of the reactions of thiols with superoxide radical by electron paramagnetic resonance: critical remarks on spectrophotometric approaches.
Dikalov S, Khramtsov V, Zimmer G
(1996) Arch Biochem Biophys 326: 207-18
MeSH Terms: Adrenochrome, Cyclic N-Oxides, Cytochrome c Group, Electron Spin Resonance Spectroscopy, Evaluation Studies as Topic, In Vitro Techniques, Kinetics, NADPH-Ferrihemoprotein Reductase, Naphthoquinones, Oxidation-Reduction, Spectrophotometry, Spin Labels, Sulfhydryl Compounds, Superoxides
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Circadian rhythms of gene expression in Chlamydomonas reinhardtii: circadian cycling of mRNA abundances of cab II, and possibly of beta-tubulin and cytochrome c.
Jacobshagen S, Johnson CH
(1994) Eur J Cell Biol 64: 142-52
MeSH Terms: Animals, Carrier Proteins, Chlamydomonas reinhardtii, Circadian Rhythm, Cytochrome c Group, Gene Expression Regulation, Gene Expression Regulation, Plant, Photosynthetic Reaction Center Complex Proteins, Photosystem II Protein Complex, Plant Proteins, Protozoan Proteins, RNA, Messenger, RNA, Plant, RNA, Protozoan, Tubulin
Added February 12, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
The presteady state reaction of chemically modified cytochromes c with cytochrome oxidase.
Veerman EC, Wilms J, Dekker HL, Muijsers AO, van Buuren KJ, van Gelder BF, Osheroff N, Speck SH, Margoliash E
(1983) J Biol Chem 258: 5739-45
MeSH Terms: Animals, Cattle, Cytochrome c Group, Electron Transport Complex IV, Horses, Kinetics, Mathematics, Osmolar Concentration, Temperature
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms