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Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis.
Ho MH, Lamont RJ, Chazin WJ, Chen H, Young DF, Kumar P, Xie H
(2018) Mol Oral Microbiol 33: 430-439
MeSH Terms: Adhesins, Bacterial, Bacterial Adhesion, Biofilms, Cell Membrane, Cysteine Endopeptidases, Dental Plaque, Fibroblasts, Gingipain Cysteine Endopeptidases, Humans, Peptides, Periodontitis, Porphyromonas gingivalis, Virulence
Added March 26, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells.
Harris KG, Morosky SA, Drummond CG, Patel M, Kim C, Stolz DB, Bergelson JM, Cherry S, Coyne CB
(2015) Cell Host Microbe 18: 221-32
MeSH Terms: 3C Viral Proteases, Autophagy, Caco-2 Cells, Cysteine Endopeptidases, Enterovirus B, Human, Epithelial Cells, Gene Silencing, Genetic Testing, Host-Pathogen Interactions, Humans, RNA Interference, Receptor-Interacting Protein Serine-Threonine Kinases, Viral Proteins, Virus Replication
Added June 6, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Brezski RJ, Kinder M, Grugan KD, Soring KL, Carton J, Greenplate AR, Petley T, Capaldi D, Brosnan K, Emmell E, Watson S, Jordan RE
(2014) MAbs 6: 1265-73
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Monoclonal, Murine-Derived, Antibody-Dependent Cell Cytotoxicity, Bacterial Proteins, Blood Platelets, Cell Line, Cell Line, Tumor, Cysteine Endopeptidases, Dogs, Enzyme-Linked Immunosorbent Assay, Epitopes, Humans, Immunoglobulin Fab Fragments, Immunoglobulin G, Matrix Metalloproteinase 3, Platelet Count, Proteolysis, Rats, Rituximab
Added April 22, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R
(2012) Cell Metab 15: 691-702
MeSH Terms: 1-Acylglycerol-3-Phosphate O-Acyltransferase, Acyl Coenzyme A, Acyltransferases, Animals, CHO Cells, COS Cells, Chlorocebus aethiops, Cricetinae, Cysteine Endopeptidases, Dietary Sucrose, Fatty Liver, Hep G2 Cells, Humans, Lipid Metabolism, Lipids, Liver, Lysophospholipids, Male, Membrane Proteins, Mice, Mice, Knockout, Models, Molecular, Phosphatidic Acids, Phospholipids, Polymorphism, Genetic, Triglycerides, Up-Regulation
Added March 21, 2013
0 Communities
1 Members
0 Resources
27 MeSH Terms
Imaging protein complex formation in the autophagy pathway: analysis of the interaction of LC3 and Atg4B(C74A) in live cells using Förster resonance energy transfer and fluorescence recovery after photobleaching.
Kraft LJ, Kenworthy AK
(2012) J Biomed Opt 17: 011008
MeSH Terms: Animals, COS Cells, Cell Nucleus, Chlorocebus aethiops, Cysteine Endopeptidases, Cytoplasm, Fluorescence Recovery After Photobleaching, Fluorescence Resonance Energy Transfer, Green Fluorescent Proteins, Microscopy, Fluorescence, Microtubule-Associated Proteins, Models, Biological, Multiprotein Complexes, Single-Cell Analysis
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Temperature-sensitive mutants and revertants in the coronavirus nonstructural protein 5 protease (3CLpro) define residues involved in long-distance communication and regulation of protease activity.
Stobart CC, Lee AS, Lu X, Denison MR
(2012) J Virol 86: 4801-10
MeSH Terms: Alleles, Amino Acid Sequence, Amino Acid Substitution, Animals, Coronavirus 3C Proteases, Cricetinae, Cysteine Endopeptidases, Enzyme Activation, Gene Order, Mice, Models, Molecular, Molecular Sequence Data, Murine hepatitis virus, Mutation, Phenotype, Protein Structure, Tertiary, Sequence Alignment, Temperature, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Letter to the editor. Chemical-genetic strategy for inhibiting proteasome function in Saccharomyces cerevisiae.
Howard GC, Collins GA, Tansey WP
(2012) Yeast 29: 93-4
MeSH Terms: ATP-Binding Cassette Transporters, Cysteine Endopeptidases, DNA, Mitochondrial, Gene Deletion, Genome, Fungal, Leupeptins, Proline, Proteasome Endopeptidase Complex, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Sodium Dodecyl Sulfate, Species Specificity
Added March 10, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Inhibition of thrombin formation by active site mutated (S360A) activated protein C.
Nicolaes GA, Bock PE, Segers K, Wildhagen KC, Dahlbäck B, Rosing J
(2010) J Biol Chem 285: 22890-900
MeSH Terms: Arginine, Binding, Competitive, Blood Coagulation, Blood Coagulation Factors, Catalytic Domain, Cell Line, Cysteine Endopeptidases, Enzyme Activation, Humans, Models, Molecular, Mutation, Neoplasm Proteins, Protein C, Protein S, Protein Stability, Recombinant Proteins, Thrombin
Added January 20, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Natural killer T cell-a cat o' nine lives!
Joyce S, Gordy LE
(2010) EMBO J 29: 1475-6
MeSH Terms: Animals, Apoptosis, Cysteine Endopeptidases, Deubiquitinating Enzyme CYLD, Lymphopoiesis, Mice, Mice, Knockout, NF-kappa B, Natural Killer T-Cells, Receptors, Interleukin-7
Added May 19, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice.
Zu L, Bedja D, Fox-Talbot K, Gabrielson KL, Van Kaer L, Becker LC, Cai ZP
(2010) J Mol Cell Cardiol 49: 5-15
MeSH Terms: Animals, Cysteine Endopeptidases, Diabetes Mellitus, Glucose, Heart, Hyperglycemia, Insulin, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Myocardium, Myosin Heavy Chains, PTEN Phosphohydrolase, Proteasome Endopeptidase Complex, Streptozocin, Ubiquitin
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms