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Results: 1 to 10 of 45

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Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.
Assassi S, Wang X, Chen G, Goldmuntz E, Keyes-Elstein L, Ying J, Wallace PK, Turner J, Zheng WJ, Pascual V, Varga J, Hinchcliff ME, Bellocchi C, McSweeney P, Furst DE, Nash RA, Crofford LJ, Welch B, Pinckney A, Mayes MD, Sullivan KM
(2019) Ann Rheum Dis 78: 1371-1378
MeSH Terms: Adult, Cyclophosphamide, Down-Regulation, Female, Hematopoietic Stem Cell Transplantation, Humans, Interferons, Male, Middle Aged, Multilevel Analysis, Myeloablative Agonists, Neutrophils, Randomized Controlled Trials as Topic, Scleroderma, Systemic, Transcriptome, Transplantation Conditioning, Transplantation, Autologous, Treatment Outcome, Up-Regulation
Added March 25, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Systemic Sclerosis as an Indication for Autologous Hematopoietic Cell Transplantation: Position Statement from the American Society for Blood and Marrow Transplantation.
Sullivan KM, Majhail NS, Bredeson C, Carpenter PA, Chatterjee S, Crofford LJ, Georges GE, Nash RA, Pasquini MC, Sarantopoulos S, Storek J, Savani B, St Clair EW
(2018) Biol Blood Marrow Transplant 24: 1961-1964
MeSH Terms: Autografts, Bone Marrow Transplantation, Cyclophosphamide, Hematopoietic Stem Cell Transplantation, Humans, Randomized Controlled Trials as Topic, Scleroderma, Systemic, Societies, Medical, United States
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.
Sullivan KM, Goldmuntz EA, Keyes-Elstein L, McSweeney PA, Pinckney A, Welch B, Mayes MD, Nash RA, Crofford LJ, Eggleston B, Castina S, Griffith LM, Goldstein JS, Wallace D, Craciunescu O, Khanna D, Folz RJ, Goldin J, St Clair EW, Seibold JR, Phillips K, Mineishi S, Simms RW, Ballen K, Wener MH, Georges GE, Heimfeld S, Hosing C, Forman S, Kafaja S, Silver RM, Griffing L, Storek J, LeClercq S, Brasington R, Csuka ME, Bredeson C, Keever-Taylor C, Domsic RT, Kahaleh MB, Medsger T, Furst DE, SCOT Study Investigators
(2018) N Engl J Med 378: 35-47
MeSH Terms: Adolescent, Adult, Aged, Cyclophosphamide, Disease-Free Survival, Female, Follow-Up Studies, Hematopoietic Stem Cell Transplantation, Humans, Immunosuppressive Agents, Infections, Intention to Treat Analysis, Kaplan-Meier Estimate, Male, Middle Aged, Scleroderma, Systemic, Transplantation Conditioning, Transplantation, Autologous, Young Adult
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain.
Guedes-da-Silva FH, Batista DG, Da Silva CF, De Araújo JS, Pavão BP, Simões-Silva MR, Batista MM, Demarque KC, Moreira OC, Britto C, Lepesheva GI, Soeiro MN
(2017) Antimicrob Agents Chemother 61:
MeSH Terms: 14-alpha Demethylase Inhibitors, Animals, Chagas Disease, Cyclophosphamide, Cytochrome P-450 Enzyme System, Disease Models, Animal, Drug Administration Schedule, Female, Gene Expression, Humans, Imidazoles, Immunosuppressive Agents, Male, Mice, Models, Molecular, Nitroimidazoles, Oxadiazoles, Parasite Load, Recurrence, Survival Analysis, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Reduced-Intensity Conditioning with Fludarabine, Cyclophosphamide, and Rituximab Is Associated with Improved Outcomes Compared with Fludarabine and Busulfan after Allogeneic Stem Cell Transplantation for B Cell Malignancies.
Kennedy VE, Savani BN, Greer JP, Kassim AA, Engelhardt BG, Goodman SA, Sengsayadeth S, Chinratanalab W, Jagasia M
(2016) Biol Blood Marrow Transplant 22: 1801-1807
MeSH Terms: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, Busulfan, Calcineurin Inhibitors, Cyclophosphamide, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Humans, Leukemia, B-Cell, Methotrexate, Middle Aged, Prognosis, Retrospective Studies, Rituximab, Survival Analysis, Transplantation Conditioning, Transplantation, Homologous, Vidarabine
Added July 28, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
Pinto N, Gamazon ER, Antao N, Myers J, Stark AL, Konkashbaev A, Im HK, Diskin SJ, London WB, Ludeman SM, Maris JM, Cox NJ, Cohn SL, Dolan ME
(2014) Clin Pharmacol Ther 95: 644-52
MeSH Terms: Antineoplastic Agents, Alkylating, Brain Neoplasms, Cell Line, Tumor, Child, Cohort Studies, Cyclohexylamines, Cyclophosphamide, Disease-Free Survival, Drug Resistance, Neoplasm, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Humans, Neuroblastoma, Phenotype, Polymorphism, Single Nucleotide, Quality Control, RNA, Small Interfering, Real-Time Polymerase Chain Reaction, Risk Assessment, Treatment Failure
Added February 22, 2016
0 Communities
2 Members
0 Resources
21 MeSH Terms
Targeted Busulfan therapy with a steady-state concentration of 600-700 ng/mL in patients with sickle cell disease receiving HLA-identical sibling bone marrow transplant.
Maheshwari S, Kassim A, Yeh RF, Domm J, Calder C, Evans M, Manes B, Bruce K, Brown V, Ho R, Frangoul H, Yang E
(2014) Bone Marrow Transplant 49: 366-9
MeSH Terms: Adolescent, Age Factors, Anemia, Sickle Cell, Antilymphocyte Serum, Bone Marrow Transplantation, Busulfan, Child, Child, Preschool, Cyclophosphamide, Disease-Free Survival, Female, Follow-Up Studies, HLA Antigens, Humans, Immunosuppressive Agents, Infant, Male, Neutrophils, Siblings, Treatment Outcome
Added March 10, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Allogeneic hematopoietic stem cell transplantation for infants with idiopathic myelofibrosis.
Hussein AA, Hamadah T, Domm J, Al-Zaben A, Frangoul H
(2013) Pediatr Transplant 17: 815-9
MeSH Terms: Blood Platelets, Busulfan, Child, Preschool, Cohort Studies, Cyclophosphamide, Female, Follow-Up Studies, Graft vs Host Disease, Hematopoietic Stem Cell Transplantation, Humans, Immunosuppressive Agents, Infant, Male, Neutrophils, Primary Myelofibrosis, Stem Cells, Transplantation Conditioning, Treatment Outcome
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Less could be better: the case for reducing the dose of cyclophosphamide for children undergoing allogeneic stem cell transplant for severe aplastic anemia.
Hussein AA, Frangoul H
(2013) Pediatr Transplant 17: 326-7
MeSH Terms: Anemia, Aplastic, Antilymphocyte Serum, Cyclophosphamide, Female, Hematopoietic Stem Cell Transplantation, Humans, Immunosuppressive Agents, Male, Transplantation Conditioning, Vidarabine
Added March 7, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Risk adopted allogeneic hematopoietic stem cell transplantation using a reduced intensity regimen for children with thalassemia major.
Hussein AA, Al-Zaben A, Ghatasheh L, Natsheh A, Hammada T, Abdel-Rahman F, Abu-Jazar H, Sharma S, Najjar R, Frangoul H
(2013) Pediatr Blood Cancer 60: 1345-9
MeSH Terms: Adolescent, Adult, Antilymphocyte Serum, Busulfan, Child, Child, Preschool, Cyclophosphamide, Disease-Free Survival, Female, Follow-Up Studies, Graft Rejection, Graft Survival, Hematopoietic Stem Cell Transplantation, Humans, Immunologic Factors, Infant, Male, Myeloablative Agonists, Retrospective Studies, Risk Factors, Survival Rate, Tissue Donors, Transplantation Conditioning, Transplantation, Homologous, Vidarabine, beta-Thalassemia
Added March 7, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms