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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 114

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Detection of Cyclooxygenase-2-Derived Oxygenation Products of the Endogenous Cannabinoid 2-Arachidonoylglycerol in Mouse Brain.
Morgan AJ, Kingsley PJ, Mitchener MM, Altemus M, Patrick TA, Gaulden AD, Marnett LJ, Patel S
(2018) ACS Chem Neurosci 9: 1552-1559
MeSH Terms: Animals, Arachidonic Acids, Brain, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Endocannabinoids, Esters, Female, Glycerides, Inflammation, Lipopolysaccharides, Male, Mice, Inbred C57BL, Mice, Transgenic, Monoacylglycerol Lipases, Neurons, Oxidation-Reduction, Prostaglandins
Added October 8, 2018
0 Communities
2 Members
0 Resources
18 MeSH Terms
Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors.
Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ
(2016) ACS Chem Biol 11: 3052-3060
MeSH Terms: Animals, Antineoplastic Agents, Cell Line, Tumor, Crystallography, X-Ray, Cyclooxygenase 2 Inhibitors, Humans, Kinetics, Mice, Mice, Nude
Added April 14, 2017
0 Communities
3 Members
0 Resources
9 MeSH Terms
Cyclooxygenase-2 inhibition reduces stress-induced affective pathology.
Gamble-George JC, Baldi R, Halladay L, Kocharian A, Hartley N, Silva CG, Roberts H, Haymer A, Marnett LJ, Holmes A, Patel S
(2016) Elife 5:
MeSH Terms: Animals, Basolateral Nuclear Complex, Behavior, Animal, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Mice, Stress, Physiological
Added March 14, 2018
0 Communities
2 Members
0 Resources
7 MeSH Terms
nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2.
Neumann W, Xu S, Sárosi MB, Scholz MS, Crews BC, Ghebreselasie K, Banerjee S, Marnett LJ, Hey-Hawkins E
(2016) ChemMedChem 11: 175-8
MeSH Terms: Animals, Binding Sites, Boranes, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Indomethacin, Mice, Models, Molecular, Molecular Structure, Sheep, Solubility, Structure-Activity Relationship
Added February 22, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways.
Chang J, Xue M, Yang S, Yao B, Zhang B, Chen X, Pozzi A, Zhang MZ
(2015) PLoS One 10: e0127030
MeSH Terms: 11-beta-Hydroxysteroid Dehydrogenases, Animals, Apoptosis, Carcinogenesis, Cell Line, Tumor, Cell Proliferation, Corticosterone, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Endoplasmic Reticulum Stress, Extracellular Signal-Regulated MAP Kinases, Glycyrrhetinic Acid, Humans, Lung Neoplasms, Male, Mice, Inbred C57BL, Models, Biological, Signal Transduction, TOR Serine-Threonine Kinases
Added October 30, 2016
1 Communities
0 Members
0 Resources
19 MeSH Terms
Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe.
Uddin MJ, Crews BC, Ghebreselasie K, Daniel CK, Kingsley PJ, Xu S, Marnett LJ
(2015) J Biomed Opt 20: 50502
MeSH Terms: Animals, Cell Line, Tumor, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Female, Image Enhancement, Infrared Rays, Mice, Mice, Nude, Microscopy, Fluorescence, Molecular Diagnostic Techniques, Molecular Imaging, Molecular Probe Techniques, Neoplasms, Experimental, Reproducibility of Results, Sensitivity and Specificity
Added February 22, 2016
0 Communities
3 Members
0 Resources
16 MeSH Terms
Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2.
Blobaum AL, Xu S, Rowlinson SW, Duggan KC, Banerjee S, Kudalkar SN, Birmingham WR, Ghebreselasie K, Marnett LJ
(2015) J Biol Chem 290: 12793-803
MeSH Terms: Animals, Catalytic Domain, Crystallography, X-Ray, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Mice, Mutation, Missense, Protein Binding, Static Electricity
Added February 22, 2016
0 Communities
2 Members
0 Resources
9 MeSH Terms
Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A.
Ra H, González-González E, Uddin MJ, King BL, Lee A, Ali-Khan I, Marnett LJ, Tang JY, Contag CH
(2015) Neoplasia 17: 201-7
MeSH Terms: Animals, Carcinoma, Basal Cell, Cyclooxygenase 2 Inhibitors, Indoles, Mice, Mice, SCID, Optical Imaging, Rhodamines, Skin Neoplasms
Added February 22, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation.
Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S
(2014) Trends Pharmacol Sci 35: 358-67
MeSH Terms: Animals, Cannabinoids, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Humans, Signal Transduction, Substrate Specificity
Added June 1, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms
Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs.
Orlando BJ, McDougle DR, Lucido MJ, Eng ET, Graham LA, Schneider C, Stokes DL, Das A, Malkowski MG
(2014) Arch Biochem Biophys 546: 33-40
MeSH Terms: Animals, Biocatalysis, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Enzyme Activation, Humans, Lipid Bilayers, Mice, Models, Molecular, Nanotechnology, Palmitic Acid, Phospholipids, Protein Conformation
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms