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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 40

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Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.
Song W, Hwang Y, Youngblood VM, Cook RS, Balko JM, Chen J, Brantley-Sieders DM
(2017) Oncogene 36: 5620-5630
MeSH Terms: Animals, Benzamides, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Cyclin-Dependent Kinase Inhibitor p27, Ephrin-A2, Female, Gene Knockdown Techniques, Humans, Mice, Mice, Inbred NOD, Mice, Nude, Mice, SCID, Neoplasm Recurrence, Local, Niacinamide, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-myb, Receptor, EphA2, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 14, 2018
0 Communities
2 Members
0 Resources
21 MeSH Terms
Phosphatidylinositol 3-kinase signaling determines kidney size.
Chen JK, Nagai K, Chen J, Plieth D, Hino M, Xu J, Sha F, Ikizler TA, Quarles CC, Threadgill DW, Neilson EG, Harris RC
(2015) J Clin Invest 125: 2429-44
MeSH Terms: Animals, Cyclin-Dependent Kinase Inhibitor p21, Cyclin-Dependent Kinase Inhibitor p27, Immunosuppressive Agents, Kidney, Kidney Diseases, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred DBA, Mice, Knockout, Multiprotein Complexes, Organ Size, Phosphatidylinositol 3-Kinases, Phosphorylation, Proto-Oncogene Proteins c-akt, Ribosomal Protein S6 Kinases, 90-kDa, Signal Transduction, Sirolimus, TOR Serine-Threonine Kinases
Added August 5, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice.
Zeng F, Miyazawa T, Kloepfer LA, Harris RC
(2014) Kidney Int 86: 538-47
MeSH Terms: Animals, Apoptosis, Blood Urea Nitrogen, Caspase 3, Cell Proliferation, Cyclin D, Cyclin-Dependent Kinase Inhibitor p21, Cyclin-Dependent Kinase Inhibitor p27, Disease Models, Animal, Disease Progression, Epithelial Cells, Fibrosis, Gene Deletion, Kidney Cortex, Kidney Medulla, Mice, Organ Size, Polycystic Kidney Diseases, Receptor, ErbB-4
Added October 27, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms
Differential regulation of cyclin-dependent kinase inhibitors in neuroblastoma cells.
Qiao L, Paul P, Lee S, Qiao J, Wang Y, Chung DH
(2013) Biochem Biophys Res Commun 435: 295-9
MeSH Terms: Cell Line, Tumor, Cyclin-Dependent Kinase Inhibitor p21, Cyclin-Dependent Kinase Inhibitor p27, Gastrin-Releasing Peptide, Gene Expression Regulation, Neoplastic, Humans, Neuroblastoma, PTEN Phosphohydrolase, Receptors, Bombesin
Added March 7, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.
Zou C, Levine EM
(2012) PLoS Genet 8: e1002924
MeSH Terms: Alleles, Animals, Cyclin-Dependent Kinase Inhibitor p27, DNA-Binding Proteins, Eye, Gene Expression Regulation, Developmental, HEK293 Cells, Homeodomain Proteins, Humans, Mice, Mice, Transgenic, Microphthalmia-Associated Transcription Factor, Mutation, Organogenesis, Otx Transcription Factors, Protein Structure, Tertiary, Retina, Transcription Factors
Added November 2, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Association of genetic polymorphisms in cell-cycle control genes and susceptibility to endometrial cancer among Chinese women.
Cai H, Xiang YB, Qu S, Long J, Cai Q, Gao J, Zheng W, Shu XO
(2011) Am J Epidemiol 173: 1263-71
MeSH Terms: Adult, Aged, Body Mass Index, Case-Control Studies, China, Cyclin-Dependent Kinase Inhibitor p27, Endometrial Neoplasms, Female, Genes, cdc, Genetic Association Studies, Genetic Predisposition to Disease, Genotype, Health Behavior, Humans, Middle Aged, Polymorphism, Single Nucleotide, Socioeconomic Factors
Added December 10, 2013
0 Communities
3 Members
0 Resources
17 MeSH Terms
Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress.
Welford SM, Dorie MJ, Li X, Haase VH, Giaccia AJ
(2010) Mol Cell Biol 30: 4595-603
MeSH Terms: Animals, Blotting, Western, Cell Proliferation, Cells, Cultured, Cellular Senescence, Cyclin-Dependent Kinase Inhibitor p27, DNA Damage, Embryo, Mammalian, Epithelial Cells, Fibroblasts, Herbicides, Kidney, Kidney Tubules, Mice, Mice, Knockout, Oxidative Stress, Oxygen, Paraquat, RNA Interference, Reverse Transcriptase Polymerase Chain Reaction, Tumor Suppressor Protein p53, Von Hippel-Lindau Tumor Suppressor Protein
Added August 19, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.
Larrea MD, Hong F, Wander SA, da Silva TG, Helfman D, Lannigan D, Smith JA, Slingerland JM
(2009) Proc Natl Acad Sci U S A 106: 9268-73
MeSH Terms: Actins, Cell Line, Tumor, Cell Movement, Cyclin-Dependent Kinase Inhibitor p27, Cytoplasm, G1 Phase, Humans, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Phosphorylation, Ribosomal Protein S6 Kinases, 90-kDa, Signal Transduction, rhoA GTP-Binding Protein
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.
Das G, Choi Y, Sicinski P, Levine EM
(2009) Neural Dev 4: 15
MeSH Terms: Animals, Animals, Newborn, Bromodeoxyuridine, Cell Cycle, Cyclin D1, Cyclin-Dependent Kinase Inhibitor p27, Embryo, Mammalian, Embryonic Stem Cells, Gene Expression Regulation, Developmental, Homeodomain Proteins, Humans, Mice, Mice, Knockout, Neurogenesis, Neurons, Otx Transcription Factors, Proliferating Cell Nuclear Antigen, Retina, Thymidine, Transcription Factor Brn-3B, Tubulin
Added November 2, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Distinct roles for p107 and p130 in Rb-independent cellular senescence.
Lehmann BD, Brooks AM, Paine MS, Chappell WH, McCubrey JA, Terrian DM
(2008) Cell Cycle 7: 1262-8
MeSH Terms: Carcinoma, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Cellular Senescence, Crk-Associated Substrate Protein, Cyclin-Dependent Kinase Inhibitor p27, DNA Damage, Down-Regulation, Genes, cdc, Humans, Male, Prostatic Neoplasms, Radiation, Retinoblastoma Protein, Retinoblastoma-Like Protein p107, Tumor Suppressor Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms