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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 169

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The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM
(2018) Biochemistry 57: 6827-6837
MeSH Terms: Amino Acid Sequence, Aminoglycosides, Bacterial Proteins, Biosynthetic Pathways, Catalytic Domain, Conserved Sequence, Crystallography, X-Ray, Gene Fusion, Genes, Bacterial, Methyltransferases, Micromonospora, Models, Molecular, Oxygenases, Protein Interaction Domains and Motifs, Sequence Homology, Amino Acid
Added April 1, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Prediction of gene regulatory enhancers across species reveals evolutionarily conserved sequence properties.
Chen L, Fish AE, Capra JA
(2018) PLoS Comput Biol 14: e1006484
MeSH Terms: Animals, Conserved Sequence, Enhancer Elements, Genetic, Evolution, Molecular, Genomics, Humans, Machine Learning, Mammals, Neural Networks, Computer, Sequence Alignment, Sequence Analysis, DNA, Support Vector Machine
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Gene Regulatory Enhancers with Evolutionarily Conserved Activity Are More Pleiotropic than Those with Species-Specific Activity.
Fish A, Chen L, Capra JA
(2017) Genome Biol Evol 9: 2615-2625
MeSH Terms: Animals, Callithrix, Cats, Cattle, Conserved Sequence, Databases, Genetic, Dogs, Enhancer Elements, Genetic, Evolution, Molecular, Genetic Pleiotropy, Histones, Humans, Macaca mulatta, Mice, Rabbits, Rats, Swine
Added March 14, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Use of a neutralizing antibody helps identify structural features critical for binding of toxin TcdA to the host cell surface.
Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB
(2017) J Biol Chem 292: 14401-14412
MeSH Terms: Amino Acid Sequence, Anti-Bacterial Agents, Antibodies, Monoclonal, Humanized, Antibodies, Neutralizing, Bacterial Proteins, Bacterial Toxins, Binding Sites, Antibody, Caco-2 Cells, Clostridioides difficile, Conserved Sequence, Crystallography, X-Ray, Enterocytes, Enterotoxins, Epitope Mapping, Glucosyltransferases, Humans, Immunoglobulin Fab Fragments, Models, Molecular, Peptide Fragments, Protein Conformation, Protein Interaction Domains and Motifs, Recombinant Proteins, Repetitive Sequences, Amino Acid
Added March 15, 2018
0 Communities
3 Members
0 Resources
23 MeSH Terms
Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors.
Prokop S, Perry NA, Vishnivetskiy SA, Toth AD, Inoue A, Milligan G, Iverson TM, Hunyady L, Gurevich VV
(2017) Cell Signal 36: 98-107
MeSH Terms: Amino Acid Sequence, Animals, Arrestins, COS Cells, Cattle, Chlorocebus aethiops, Conserved Sequence, HEK293 Cells, Humans, Lysine, Mutant Proteins, Mutation, Protein Binding, Protein Structure, Secondary, Receptors, G-Protein-Coupled, Rhodopsin
Added March 14, 2018
0 Communities
2 Members
0 Resources
16 MeSH Terms
Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.
Thomas LR, Foshage AM, Weissmiller AM, Popay TM, Grieb BC, Qualls SJ, Ng V, Carboneau B, Lorey S, Eischen CM, Tansey WP
(2016) Oncogene 35: 3613-8
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Cell Transformation, Neoplastic, Conserved Sequence, Evolution, Molecular, HEK293 Cells, Host Cell Factor C1, Humans, Immunoprecipitation, Mice, Mutation, NIH 3T3 Cells, Protein Binding, Proto-Oncogene Proteins c-myc, Sequence Homology, Amino Acid
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Beckley JR, Chen JS, Yang Y, Peng J, Gould KL
(2015) Mol Cell Proteomics 14: 3132-41
MeSH Terms: Cell Membrane, Cell Polarity, Conserved Sequence, Endopeptidases, Humans, Protein Transport, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Substrate Specificity
Added February 4, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein.
Nordman JT, Orr-Weaver TL
(2015) Bioessays 37: 856-61
MeSH Terms: Amino Acid Sequence, Animals, Chromosome Fragility, Conserved Sequence, DNA Replication, DNA-Binding Proteins, Drosophila Proteins, Drosophila melanogaster, Humans, Molecular Sequence Data
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition.
Cherkesova TS, Hargrove TY, Vanrell MC, Ges I, Usanov SA, Romano PS, Lepesheva GI
(2014) FEBS Lett 588: 3878-85
MeSH Terms: 14-alpha Demethylase Inhibitors, Amino Acid Sequence, Amino Acid Substitution, Animals, Biocatalysis, Chagas Disease, Conserved Sequence, Cytochrome P-450 Enzyme System, Humans, Models, Molecular, Molecular Sequence Data, Protein Conformation, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices.
Schlebach JP, Sanders CR
(2015) J Membr Biol 248: 371-81
MeSH Terms: Amino Acid Sequence, Animals, Cattle, Conserved Sequence, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, KCNQ1 Potassium Channel, Lipid Bilayers, Mutation, Mutation, Missense, Myelin Proteins, Protein Structure, Secondary, Protein Transport, Receptors, Vasopressin, Rhodopsin, Thermodynamics
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms