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Results: 1 to 10 of 24

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The altered mechanical phenotype of fetal fibroblasts hinders myofibroblast differentiation.
Jerrell RJ, Leih MJ, Parekh A
(2019) Wound Repair Regen 27: 29-38
MeSH Terms: Adult, Cell Differentiation, Cells, Cultured, Cicatrix, Collagen Type III, Extracellular Matrix, Female, Fetus, Fibroblasts, Gene Expression Regulation, Humans, Male, Myofibroblasts, Phenotype, Pregnancy, Transforming Growth Factor beta1, Wound Healing, Young Adult
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds.
Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F
(2018) Tissue Eng Part A 24: 1531-1544
MeSH Terms: Adult, Cells, Cultured, Chondrogenesis, Collagen Type II, Core Binding Factor Alpha 1 Subunit, Extracellular Matrix, Gene Knockdown Techniques, Genetic Engineering, Glycosaminoglycans, Humans, Mesenchymal Stem Cells, Minerals, Osteogenesis, Smad3 Protein, Tissue Engineering, Tissue Scaffolds, Transforming Growth Factor beta3
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.
Karolak MR, Yang X, Elefteriou F
(2015) Hum Mol Genet 24: 2552-64
MeSH Terms: Animals, Chondrocytes, Chondrogenesis, Collagen Type II, Female, Gene Expression, Gene Knockout Techniques, Growth Plate, Hypertrophy, Male, Mice, Mice, Knockout, Neurofibromin 1, Osteoclasts, Osteogenesis, Phenotype, Phenylurea Compounds, Protein Transport, Pyrimidines, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 3, Signal Transduction
Added February 19, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Asfotase-╬▒ improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F
(2014) Nat Med 20: 904-10
MeSH Terms: Adolescent, Alkaline Phosphatase, Animals, Bone Development, Bone Diseases, Developmental, Bone Morphogenetic Protein 2, Calcification, Physiologic, Cells, Cultured, Child, Child, Preschool, Collagen Type I, Collagen Type I, alpha 1 Chain, Collagen Type II, Diphosphates, Disease Models, Animal, Durapatite, Humans, Immunoglobulin G, Infant, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Neurofibromatosis 1, Neurofibromin 1, Osteoblasts, Osteogenesis, Phosphate Transport Proteins, Phosphoric Diester Hydrolases, Pyrophosphatases, Recombinant Fusion Proteins, Sp7 Transcription Factor, Transcription Factors
Added July 28, 2014
2 Communities
4 Members
0 Resources
33 MeSH Terms
Genetic epidemiology of pelvic organ prolapse: a systematic review.
Ward RM, Velez Edwards DR, Edwards T, Giri A, Jerome RN, Wu JM
(2014) Am J Obstet Gynecol 211: 326-35
MeSH Terms: Collagen Type III, Female, Genetic Markers, Genetic Predisposition to Disease, Genome-Wide Association Study, Global Health, Humans, Models, Statistical, Molecular Epidemiology, Odds Ratio, Pelvic Organ Prolapse, Polymorphism, Single Nucleotide
Added February 22, 2016
0 Communities
2 Members
0 Resources
12 MeSH Terms
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.
Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ
(2013) Prostaglandins Leukot Essent Fatty Acids 89: 351-8
MeSH Terms: Animals, Arthritis, Experimental, Autoantibodies, Chromatography, Liquid, Collagen Type II, Dinoprostone, Female, Gene Deletion, Inflammation, Intramolecular Oxidoreductases, Joints, Lipid Metabolism, Macrophages, Male, Mice, Neutrophil Infiltration, Neutrophils, Prostaglandin-E Synthases, Severity of Illness Index, Tandem Mass Spectrometry
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Vascular Ehlers-Danlos syndrome mutations in type III collagen differently stall the triple helical folding.
Mizuno K, Boudko S, Engel J, B├Ąchinger HP
(2013) J Biol Chem 288: 19166-76
MeSH Terms: Circular Dichroism, Collagen, Collagen Type III, Ehlers-Danlos Syndrome, Humans, Mutation, Peptidylprolyl Isomerase, Point Mutation, Protein Folding, Protein Processing, Post-Translational, Protein Structure, Secondary, Protein Structure, Tertiary, Recombinant Proteins, Temperature, Trypsin
Added November 2, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh.
Wang W, Lian N, Ma Y, Li L, Gallant RC, Elefteriou F, Yang X
(2012) Development 139: 601-11
MeSH Terms: Activating Transcription Factor 4, Animals, Bone Development, Cell Differentiation, Cells, Cultured, Chondrocytes, Collagen Type II, Female, Growth Plate, Hedgehog Proteins, Integrin-Binding Sialoprotein, Male, Mice, Mice, Transgenic, Osteoblasts, Osteocalcin, Osteogenesis
Added November 14, 2013
0 Communities
2 Members
0 Resources
17 MeSH Terms
Vascular endothelial cadherin modulates renal interstitial fibrosis.
Yamaguchi I, Tchao BN, Burger ML, Yamada M, Hyodo T, Giampietro C, Eddy AA
(2012) Nephron Exp Nephrol 120: e20-31
MeSH Terms: Animals, Antigens, Antigens, CD, Antigens, Differentiation, Myelomonocytic, Blotting, Western, Cadherins, Capillary Permeability, Collagen Type I, Collagen Type III, Disease Models, Animal, Fibronectins, Fibrosis, Gene Expression, Heterozygote, Immunohistochemistry, Kidney, Macrophages, Mice, Mice, Knockout, Myofibroblasts, Proteoglycans, Renal Circulation, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Ureteral Obstruction
Added February 3, 2012
0 Communities
1 Members
0 Resources
25 MeSH Terms
Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Wang W, Nyman JS, Ono K, Stevenson DA, Yang X, Elefteriou F
(2011) Hum Mol Genet 20: 3910-24
MeSH Terms: Animals, Bone Diseases, Developmental, Bone Remodeling, Bone and Bones, Chondrocytes, Collagen Type II, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Female, Intervertebral Disc, Lovastatin, Mice, Mice, Knockout, Neurofibromatosis 1, Neurofibromin 1, Osteoblasts, Osteocytes, Osteogenesis, Phenotype, Porosity, Promoter Regions, Genetic, Recombination, Genetic, Stem Cells, ras Proteins
Added November 14, 2013
1 Communities
3 Members
0 Resources
24 MeSH Terms