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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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Selective inhibition of M muscarinic acetylcholine receptors attenuates cocaine self-administration in rats.
Gunter BW, Gould RW, Bubser M, McGowan KM, Lindsley CW, Jones CK
(2018) Addict Biol 23: 1106-1116
MeSH Terms: Animals, Behavior, Animal, Cocaine, Cocaine-Related Disorders, Conditioning, Operant, Disease Models, Animal, Dopamine Uptake Inhibitors, Dose-Response Relationship, Drug, Male, Mice, Rats, Rats, Sprague-Dawley, Receptor, Muscarinic M5, Reinforcement Schedule, Reward, Self Administration
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems.
Marasco CC, Goodwin CR, Winder DG, Schramm-Sapyta NL, McLean JA, Wikswo JP
(2014) Exp Biol Med (Maywood) 239: 1433-42
MeSH Terms: Cocaine-Related Disorders, Humans, Immune System, Nervous System, Systems Biology
Added August 21, 2014
1 Communities
3 Members
0 Resources
5 MeSH Terms
Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data.
Goodwin CR, Sherrod SD, Marasco CC, Bachmann BO, Schramm-Sapyta N, Wikswo JP, McLean JA
(2014) Anal Chem 86: 6563-71
MeSH Terms: Algorithms, Animals, Cluster Analysis, Cocaine-Related Disorders, Mass Spectrometry, Metabolome, Metabolomics, Multivariate Analysis, Phenotype, Rats, Workflow
Added May 29, 2014
2 Communities
2 Members
0 Resources
11 MeSH Terms
Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.
Dhanya RP, Sheffler DJ, Dahl R, Davis M, Lee PS, Yang L, Nickols HH, Cho HP, Smith LH, D'Souza MS, Conn PJ, Der-Avakian A, Markou A, Cosford ND
(2014) J Med Chem 57: 4154-72
MeSH Terms: Allosteric Regulation, Animals, Cocaine-Related Disorders, Disease Models, Animal, Dose-Response Relationship, Drug, Drug Design, HEK293 Cells, Humans, Male, Rats, Rats, Wistar, Receptors, Metabotropic Glutamate
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
A shift in the role of glutamatergic signaling in the nucleus accumbens core with the development of an addicted phenotype.
Doyle SE, Ramôa C, Garber G, Newman J, Toor Z, Lynch WJ
(2014) Biol Psychiatry 76: 810-5
MeSH Terms: 6-Cyano-7-nitroquinoxaline-2,3-dione, Animals, Cocaine, Cocaine-Related Disorders, Conditioning, Operant, Excitatory Amino Acid Antagonists, Extinction, Psychological, Female, Glutamic Acid, Male, Motivation, Nucleus Accumbens, Phenotype, Rats, Rats, Sprague-Dawley, Receptors, AMPA, Receptors, Kainic Acid, Reinforcement Schedule, Self Administration
Added March 20, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Cocaine enhances HIV-1-induced CD4(+) T-cell apoptosis: implications in disease progression in cocaine-abusing HIV-1 patients.
Pandhare J, Addai AB, Mantri CK, Hager C, Smith RM, Barnett L, Villalta F, Kalams SA, Dash C
(2014) Am J Pathol 184: 927-936
MeSH Terms: Apoptosis, CD4-Positive T-Lymphocytes, Cell Separation, Cocaine, Cocaine-Related Disorders, Disease Progression, Dopamine Uptake Inhibitors, Flow Cytometry, HIV Infections, HIV-1, Humans, Virion
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence.
Anastasio NC, Stutz SJ, Fox RG, Sears RM, Emeson RB, DiLeone RJ, O'Neil RT, Fink LH, Li D, Green TA, Moeller FG, Cunningham KA
(2014) Neuropsychopharmacology 39: 370-82
MeSH Terms: Animals, Behavior, Animal, Cocaine-Related Disorders, Male, Phenotype, Prefrontal Cortex, Rats, Rats, Sprague-Dawley, Receptor, Serotonin, 5-HT2C, Recurrence, Self Administration
Added May 28, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction.
Amato RJ, Felts AS, Rodriguez AL, Venable DF, Morrison RD, Byers FW, Daniels JS, Niswender CM, Conn PJ, Lindsley CW, Jones CK, Emmitte KA
(2013) ACS Chem Neurosci 4: 1217-28
MeSH Terms: Allosteric Regulation, Aminopyridines, Animals, Brain, Cocaine-Related Disorders, Disease Models, Animal, Liver, Phenylurea Compounds, Rats, Receptor, Metabotropic Glutamate 5, Structure-Activity Relationship, Urea
Added February 19, 2015
0 Communities
3 Members
0 Resources
12 MeSH Terms
GLP-1 analog attenuates cocaine reward.
Graham DL, Erreger K, Galli A, Stanwood GD
(2013) Mol Psychiatry 18: 961-2
MeSH Terms: Animals, Brain, Cocaine-Related Disorders, Conditioning, Operant, Disease Models, Animal, Dose-Response Relationship, Drug, Exenatide, Exploratory Behavior, Glucagon-Like Peptide 1, Male, Mice, Mice, Inbred C57BL, Peptides, Reward, Venoms
Added February 19, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Active cocaine use is associated with lack of HIV-1 virologic suppression independent of nonadherence to antiretroviral therapy: use of a rapid screening tool during routine clinic visits.
Rasbach DA, Desruisseau AJ, Kipp AM, Stinnette S, Kheshti A, Shepherd BE, Sterling TR, Hulgan T, McGowan CC, Qian HZ
(2013) AIDS Care 25: 109-17
MeSH Terms: Adult, Ambulatory Care, Anti-HIV Agents, Cocaine-Related Disorders, Cross-Sectional Studies, Female, HIV Infections, HIV-1, Humans, Male, Mass Screening, Middle Aged, Odds Ratio, Patient Compliance, RNA, Viral, Treatment Outcome, Viral Load, Young Adult
Added December 10, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms