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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 20

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Co-Prescription of Strong CYP1A2 Inhibitors and the Risk of Tizanidine-Associated Hypotension: A Retrospective Cohort Study.
Chaugai S, Dickson AL, Shuey MM, Feng Q, Barker KA, Wei WQ, Luther JM, Stein CM, Chung CP
(2019) Clin Pharmacol Ther 105: 703-709
MeSH Terms: Adult, Clonidine, Cohort Studies, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1A2 Inhibitors, Drug Therapy, Combination, Female, Humans, Hypotension, Male, Middle Aged, Muscle Relaxants, Central, Polypharmacy, Retrospective Studies, Risk Factors
Added October 25, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
α- and α-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands.
Sánchez-Soto M, Casadó-Anguera V, Yano H, Bender BJ, Cai NS, Moreno E, Canela EI, Cortés A, Meiler J, Casadó V, Ferré S
(2018) Mol Neurobiol 55: 8438-8454
MeSH Terms: Adenylyl Cyclases, Animals, Cerebral Cortex, Clonidine, Dopamine, Extracellular Signal-Regulated MAP Kinases, GTP-Binding Proteins, HEK293 Cells, Humans, Idazoxan, Ligands, Neostriatum, Norepinephrine, Phosphorylation, Quinpirole, Receptors, Adrenergic, alpha-2, Receptors, Dopamine, Sheep, Tetrahydronaphthalenes
Added March 21, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism.
Al-Hasani R, McCall JG, Foshage AM, Bruchas MR
(2013) Neuropsychopharmacology 38: 2484-97
MeSH Terms: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer, Adrenergic alpha-2 Receptor Agonists, Adrenergic beta-1 Receptor Antagonists, Adrenergic beta-Antagonists, Animals, Betaxolol, Clonidine, Cocaine, Conditioning, Psychological, Drug-Seeking Behavior, Locus Coeruleus, Male, Mice, Mice, Inbred C57BL, Naltrexone, Propanolamines, Propranolol, Receptors, Adrenergic, alpha, Receptors, Adrenergic, beta, Receptors, Opioid, kappa
Added May 15, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Decreasing adrenergic or sympathetic hyperactivity after severe traumatic brain injury using propranolol and clonidine (DASH After TBI Study): study protocol for a randomized controlled trial.
Patel MB, McKenna JW, Alvarez JM, Sugiura A, Jenkins JM, Guillamondegui OD, Pandharipande PP
(2012) Trials 13: 177
MeSH Terms: Adrenergic Fibers, Adrenergic alpha-2 Receptor Agonists, Adrenergic beta-Antagonists, Biomarkers, Brain Injuries, Catecholamines, Clonidine, Cognition, Double-Blind Method, Drug Administration Schedule, Drug Therapy, Combination, Glasgow Coma Scale, Hemodynamics, Humans, Neurologic Examination, Neuropsychological Tests, Propranolol, Quality of Life, Research Design, Sympathetic Nervous System, Tennessee, Time Factors, Treatment Outcome
Added June 14, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Effects of the α₂-adrenergic agonist clonidine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine in healthy volunteers.
Hysek CM, Brugger R, Simmler LD, Bruggisser M, Donzelli M, Grouzmann E, Hoener MC, Liechti ME
(2012) J Pharmacol Exp Ther 340: 286-94
MeSH Terms: 3,4-Methylenedioxyamphetamine, Adrenergic alpha-2 Receptor Agonists, Adult, Affect, Blood Pressure, Body Temperature, Brain, Clonidine, Consciousness, Cross-Over Studies, Double-Blind Method, Drug Interactions, Emotions, Epinephrine, Female, Heart Rate, Humans, Male, Mental Processes, N-Methyl-3,4-methylenedioxyamphetamine, Norepinephrine, Young Adult
Added August 3, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy.
Moss JR, Cofer S, Hersey S, Goudy S, Werkhaven J, Swanson E, Mantle C, Stowell N, Byrne D, Wang L, Labadie R
(2011) Arch Otolaryngol Head Neck Surg 137: 591-7
MeSH Terms: Adenoids, Adolescent, Age Factors, Analgesics, Anesthetics, Local, Bupivacaine, Child, Child, Preschool, Clonidine, Dehydration, Diet, Double-Blind Method, Drug Therapy, Combination, Female, Humans, Hypertrophy, Injections, Lidocaine, Male, Multivariate Analysis, Pain Measurement, Pain, Postoperative, Palatine Tonsil, Premedication, Prospective Studies, Sleep Apnea Syndromes, Tonsillectomy, Tonsillitis
Added May 30, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization.
Lu R, Li Y, Zhang Y, Chen Y, Shields AD, Winder DG, Angelotti T, Jiao K, Limbird LE, Zhou Y, Wang Q
(2009) J Biol Chem 284: 13233-43
MeSH Terms: Adrenergic alpha-Agonists, Animals, Blotting, Southern, Brain, Calcium, Cells, Cultured, Clonidine, Electrophysiology, Endocytosis, Fluorescent Antibody Technique, GTP-Binding Proteins, Guanfacine, Guanosine 5'-O-(3-Thiotriphosphate), Hemagglutinins, Humans, Immunoenzyme Techniques, Integrases, Kidney, Male, Mice, Mice, Inbred C57BL, Neurons, Norepinephrine, Phosphorylation, Protein Binding, Receptors, Adrenergic, alpha-2, Signal Transduction, Sympathetic Nervous System, Transfection
Added August 13, 2010
1 Communities
1 Members
0 Resources
29 MeSH Terms
alpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice.
Billings FT, Chen SW, Kim M, Park SW, Song JH, Wang S, Herman J, D'Agati V, Lee HT
(2008) Am J Physiol Renal Physiol 295: F741-8
MeSH Terms: Adrenergic alpha-Agonists, Animals, Cell Line, Clonidine, Contrast Media, Dexmedetomidine, Iohexol, Kidney Diseases, Kidney Medulla, Male, Mice, Mice, Inbred C57BL, Renal Circulation
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure.
Shibao C, Gamboa A, Abraham R, Raj SR, Diedrich A, Black B, Robertson D, Biaggioni I
(2006) Hypertension 47: 522-6
MeSH Terms: Aged, Aged, 80 and over, Antihypertensive Agents, Autonomic Nervous System, Autonomic Nervous System Diseases, Blood Pressure, Clonidine, Female, Humans, Hypertension, Hypotension, Orthostatic, Male, Middle Aged, Natriuresis, Nitroglycerin, Supine Position, Sympathetic Nervous System, Sympatholytics, Vasodilator Agents
Added December 10, 2013
0 Communities
4 Members
0 Resources
19 MeSH Terms
Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists.
Tan CM, Wilson MH, MacMillan LB, Kobilka BK, Limbird LE
(2002) Proc Natl Acad Sci U S A 99: 12471-6
MeSH Terms: Adrenergic alpha-Agonists, Animals, Blood Pressure, Clonidine, Dexmedetomidine, Epinephrine, Heterozygote, Hypnotics and Sedatives, Imidazoles, In Vitro Techniques, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Receptors, Adrenergic, alpha-2
Added September 30, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms