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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 2 of 2

Publication Record


Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF, Newman AH, Blakely RD
(2006) J Biol Chem 281: 2012-23
MeSH Terms: Adrenergic Uptake Inhibitors, Amino Acid Sequence, Animals, Antidepressive Agents, Binding Sites, Binding, Competitive, Blotting, Western, Cadmium, Cell Line, Cell Membrane, Citalopram, Clomipramine, Cocaine, Cysteine, Dopamine Uptake Inhibitors, Fluoxetine, HeLa Cells, Humans, Immunoprecipitation, Isoleucine, Kinetics, LLC-PK1 Cells, Mazindol, Methionine, Mice, Models, Chemical, Molecular Sequence Data, Mutation, N-Methyl-3,4-methylenedioxyamphetamine, Nomifensine, Protein Binding, Protein Structure, Tertiary, Protein Transport, Radiopharmaceuticals, Receptors, Serotonin, Serotonin, Serotonin Uptake Inhibitors, Species Specificity, Stereoisomerism, Substrate Specificity, Tyrosine
Added July 10, 2013
2 Communities
1 Members
0 Resources
41 MeSH Terms
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
Meredith EJ, Holder MJ, Chamba A, Challa A, Drake-Lee A, Bunce CM, Drayson MT, Pilkington G, Blakely RD, Dyer MJ, Barnes NM, Gordon J
(2005) FASEB J 19: 1187-9
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Antineoplastic Agents, Apoptosis, Burkitt Lymphoma, Cell Line, Tumor, Clomipramine, Fenfluramine, Fluoxetine, Humans, Lymphoma, B-Cell, N-Methyl-3,4-methylenedioxyamphetamine, Proto-Oncogene Proteins c-bcl-2, Psychotropic Drugs, Serotonin Plasma Membrane Transport Proteins
Added July 10, 2013
1 Communities
1 Members
0 Resources
14 MeSH Terms