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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 16

Publication Record


Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.
Gowrikumar S, Ahmad R, Uppada SB, Washington MK, Shi C, Singh AB, Dhawan P
(2019) Oncogene 38: 5321-5337
MeSH Terms: Animals, Biomarkers, Tumor, Cells, Cultured, Claudin-1, Colitis, Colonic Neoplasms, Gene Expression Regulation, Neoplastic, HT29 Cells, Humans, Inflammatory Bowel Diseases, Intestinal Mucosa, Mice, Mice, Inbred C57BL, Mice, Transgenic, Phosphorylation, Prognosis, Protein Processing, Post-Translational, Proto-Oncogene Proteins c-akt, Receptors, Notch, Signal Transduction, Up-Regulation, beta Catenin
Added April 24, 2019
1 Communities
0 Members
0 Resources
22 MeSH Terms
Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ₁ domain of zonula occludens.
Wu J, Peng D, Zhang Y, Lu Z, Voehler M, Sanders CR, Li J
(2015) Biochem Biophys Res Commun 459: 87-93
MeSH Terms: Amino Acid Motifs, Claudin-1, Claudin-2, Claudin-3, Claudin-5, Claudins, Humans, Nuclear Magnetic Resonance, Biomolecular, Peripheral Nerves, Protein Structure, Secondary, Zonula Occludens-2 Protein
Added February 5, 2016
1 Communities
1 Members
0 Resources
11 MeSH Terms
Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ.
Suarez S, McCollum GW, Bretz CA, Yang R, Capozzi ME, Penn JS
(2014) Invest Ophthalmol Vis Sci 55: 8232-40
MeSH Terms: Analysis of Variance, Animals, Capillary Permeability, Cell Membrane, Cells, Cultured, Claudin-1, Claudin-5, Electric Impedance, Endothelial Cells, Extracellular Signal-Regulated MAP Kinases, Humans, Immunohistochemistry, MAP Kinase Signaling System, Mice, Mice, Inbred C57BL, Models, Animal, Peroxisome Proliferator-Activated Receptors, Receptors, Vascular Endothelial Growth Factor, Retina, Retinal Vessels, Sulfones, Thiophenes, Vascular Endothelial Growth Factor A
Added February 19, 2015
1 Communities
1 Members
0 Resources
23 MeSH Terms
Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis.
Pope JL, Ahmad R, Bhat AA, Washington MK, Singh AB, Dhawan P
(2014) Mol Cancer 13: 167
MeSH Terms: Adenomatous Polyposis Coli, Adenomatous Polyposis Coli Protein, Animals, Cell Transformation, Neoplastic, Claudin-1, Colonic Neoplasms, Epithelial Cells, Gene Expression Regulation, Neoplastic, Interleukin-23 Subunit p19, Intestinal Mucosa, Intestines, Mice, Mucin-2
Added December 8, 2014
1 Communities
1 Members
0 Resources
13 MeSH Terms
Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells.
Sharma A, Bhat AA, Krishnan M, Singh AB, Dhawan P
(2013) Carcinogenesis 34: 2610-21
MeSH Terms: 3' Untranslated Regions, Base Sequence, Blotting, Western, Breast Neoplasms, Cells, Cultured, Chromatin Immunoprecipitation, Claudin-1, Colonic Neoplasms, ELAV Proteins, Epigenesis, Genetic, Female, Fluorescent Antibody Technique, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Immunoenzyme Techniques, Kidney, Molecular Sequence Data, Mutagenesis, Site-Directed, RNA, Messenger, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Tristetraprolin
Added March 7, 2014
0 Communities
2 Members
0 Resources
24 MeSH Terms
Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling.
Pope JL, Bhat AA, Sharma A, Ahmad R, Krishnan M, Washington MK, Beauchamp RD, Singh AB, Dhawan P
(2014) Gut 63: 622-34
MeSH Terms: Animals, Apoptosis, Cell Differentiation, Cell Proliferation, Claudin-1, Colitis, Colon, Dextran Sulfate, Disease Models, Animal, Homeostasis, Intestinal Mucosa, Mice, Mice, Inbred C57BL, Mice, Transgenic, Real-Time Polymerase Chain Reaction, Receptors, Notch, Signal Transduction
Added January 20, 2014
1 Communities
7 Members
0 Resources
17 MeSH Terms
Rab25 regulates integrin expression in polarized colonic epithelial cells.
Krishnan M, Lapierre LA, Knowles BC, Goldenring JR
(2013) Mol Biol Cell 24: 818-31
MeSH Terms: Adenovirus E1A Proteins, Caco-2 Cells, Cell Line, Tumor, Cell Movement, Cell Polarity, Claudin-1, Epithelial Cells, Gene Expression Regulation, Gene Expression Regulation, Neoplastic, HEK293 Cells, Humans, Integrin alpha2, Integrin alpha5, Integrin alpha5beta1, Integrin beta1, Integrins, Intestinal Mucosa, Microvilli, Neoplasm Invasiveness, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-ets, RNA Interference, rab GTP-Binding Proteins
Added October 7, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
Claudin-1 expression confers resistance to anoikis in colon cancer cells in a Src-dependent manner.
Singh AB, Sharma A, Dhawan P
(2012) Carcinogenesis 33: 2538-47
MeSH Terms: Anoikis, Cell Line, Tumor, Claudin-1, Colonic Neoplasms, Humans, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins c-bcl-2, src-Family Kinases
Added March 7, 2014
0 Communities
2 Members
0 Resources
8 MeSH Terms
Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.
Bhat AA, Sharma A, Pope J, Krishnan M, Washington MK, Singh AB, Dhawan P
(2012) PLoS One 7: e37174
MeSH Terms: Base Sequence, Binding Sites, CDX2 Transcription Factor, Cell Line, Tumor, Claudin-1, Colorectal Neoplasms, DNA, GATA4 Transcription Factor, Gene Expression Regulation, Homeodomain Proteins, Humans, Molecular Sequence Data, Promoter Regions, Genetic, Transcription, Genetic, Wnt Proteins
Added June 28, 2013
0 Communities
5 Members
0 Resources
15 MeSH Terms
Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells.
Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P
(2011) Gastroenterology 141: 2140-53
MeSH Terms: Anoikis, Cadherins, Cell Line, Tumor, Claudin-1, Colonic Neoplasms, Disease Progression, Gene Expression Regulation, Neoplastic, Homeodomain Proteins, Humans, Immunoblotting, Membrane Proteins, Microarray Analysis, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Transcription Factors, Up-Regulation, Zinc Finger E-box-Binding Homeobox 1
Added June 14, 2013
2 Communities
3 Members
0 Resources
18 MeSH Terms