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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.
Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A
(2017) Clin Cancer Res 23: 3371-3384
MeSH Terms: Aminopyridines, Animals, Cell Line, Tumor, Cell Proliferation, Class Ib Phosphatidylinositol 3-Kinase, Female, Humans, Immunity, Cellular, Mammary Neoplasms, Animal, Mice, Morpholines, Neoplasm Metastasis, Phosphoinositide-3 Kinase Inhibitors, Programmed Cell Death 1 Receptor, Protein Kinase Inhibitors, Signal Transduction, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added January 4, 2017
2 Communities
4 Members
0 Resources
18 MeSH Terms
Targeting nonclassical oncogenes for therapy in T-ALL.
Subramaniam PS, Whye DW, Efimenko E, Chen J, Tosello V, De Keersmaecker K, Kashishian A, Thompson MA, Castillo M, Cordon-Cardo C, Davé UP, Ferrando A, Lannutti BJ, Diacovo TG
(2012) Cancer Cell 21: 459-72
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Binding Sites, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Class I Phosphatidylinositol 3-Kinases, Class Ib Phosphatidylinositol 3-Kinase, Drug Design, Gene Silencing, Humans, Mice, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Protein Isoforms, Purines, Quinazolinones
Added March 5, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.
Chen S, Lin F, Shin ME, Wang F, Shen L, Hamm HE
(2008) Mol Biol Cell 19: 3909-22
MeSH Terms: Cell Movement, Chemotaxis, Class Ib Phosphatidylinositol 3-Kinase, Enzyme Inhibitors, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, GTP-Binding Proteins, Gene Expression Regulation, HL-60 Cells, Humans, Isoenzymes, Jurkat Cells, Models, Molecular, Models, Theoretical, Neoplasm Proteins, Neutrophils, Phosphatidylinositol 3-Kinases, Phospholipase C beta, RNA, Small Interfering, Receptors for Activated C Kinase, Receptors, Cell Surface
Added December 10, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms