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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver.
Deja S, Fu X, Fletcher JA, Kucejova B, Browning JD, Young JD, Burgess SC
(2020) Metab Eng 59: 1-14
MeSH Terms: Animals, Carbon Isotopes, Citric Acid Cycle, Gluconeogenesis, Liver, Male, Mice, Models, Biological, Nuclear Magnetic Resonance, Biomolecular, Pentose Phosphate Pathway
Added March 5, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Regulation of leukocyte function by citric acid cycle intermediates.
Patil NK, Bohannon JK, Hernandez A, Patil TK, Sherwood ER
(2019) J Leukoc Biol 106: 105-117
MeSH Terms: Animals, Citric Acid, Citric Acid Cycle, Fumarates, Humans, Leukocytes, Reactive Oxygen Species, Succinates, Succinic Acid
Added March 18, 2020
0 Communities
2 Members
0 Resources
9 MeSH Terms
Glutamate-oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux.
Egnatchik RA, Leamy AK, Sacco SA, Cheah YE, Shiota M, Young JD
(2019) J Biol Chem 294: 3081-3090
MeSH Terms: Animals, Aspartate Aminotransferases, Cell Death, Cell Line, Citric Acid Cycle, Extracellular Space, Glutamine, Hepatocytes, Ketoglutaric Acids, Male, Oxidative Stress, Oxygen, Palmitates, Rats, Rats, Sprague-Dawley
Added March 28, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Glycine -methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates.
Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH
(2018) J Biol Chem 293: 11944-11954
MeSH Terms: Animals, Carbon, Citric Acid Cycle, Energy Metabolism, Fatty Liver, Gene Deletion, Gluconeogenesis, Glucose, Glycine N-Methyltransferase, Liver, Male, Metabolic Flux Analysis, Methionine, Mice, Mice, Knockout, S-Adenosylmethionine
Added March 26, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
Lactate Metabolism in Human Lung Tumors.
Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ
(2017) Cell 171: 358-371.e9
MeSH Terms: Animals, Blood Chemical Analysis, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Citric Acid Cycle, Disease Models, Animal, Female, Glyceric Acids, Heterografts, Humans, Lactic Acid, Lung Neoplasms, Male, Mice, Monocarboxylic Acid Transporters, Neoplasm Transplantation, Symporters
Added March 28, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Application of C flux analysis to identify high-productivity CHO metabolic phenotypes.
Templeton N, Smith KD, McAtee-Pereira AG, Dorai H, Betenbaugh MJ, Lang SE, Young JD
(2017) Metab Eng 43: 218-225
MeSH Terms: Animals, Antibodies, Monoclonal, CHO Cells, Carbon Isotopes, Citric Acid Cycle, Cricetulus, Gene Expression, Immunoglobulin G, Isotope Labeling, Recombinant Proteins
Added April 27, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Mass spectrometry-based microassay of (2)H and (13)C plasma glucose labeling to quantify liver metabolic fluxes in vivo.
Hasenour CM, Wall ML, Ridley DE, Hughey CC, James FD, Wasserman DH, Young JD
(2015) Am J Physiol Endocrinol Metab 309: E191-203
MeSH Terms: Animals, Biological Transport, Blood Glucose, Carbon Isotopes, Citric Acid Cycle, Deuterium, Gas Chromatography-Mass Spectrometry, Glucose, Isotope Labeling, Liver, Liver Glycogen, Male, Mice, Mice, Inbred C57BL
Added May 27, 2015
0 Communities
3 Members
0 Resources
14 MeSH Terms
Sum of the parts: mass spectrometry-based metabolomics.
Milne SB, Mathews TP, Myers DS, Ivanova PT, Brown HA
(2013) Biochemistry 52: 3829-40
MeSH Terms: Carbon Isotopes, Chromatography, Liquid, Citric Acid Cycle, Gas Chromatography-Mass Spectrometry, Glycolysis, Mass Spectrometry, Metabolomics, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added March 19, 2013
0 Communities
1 Members
0 Resources
8 MeSH Terms
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, Zhang H, Zimmerman LJ, Liebler DC, Slebos RJ, Lorkiewicz PK, Higashi RM, Fan TW, Dang CV
(2012) Cell Metab 15: 110-21
MeSH Terms: B-Lymphocytes, Carbon Isotopes, Cell Hypoxia, Cell Line, Tumor, Cell Proliferation, Cell Survival, Citric Acid, Citric Acid Cycle, Fumarates, Glucose, Glutaminase, Glutamine, Humans, Isotope Labeling, Malates, Oxidation-Reduction, Sulfides, Thiadiazoles
Added March 12, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Tracking cellular metabolomics in lipoapoptosis- and steatosis-developing liver cells.
Noguchi Y, Young JD, Aleman JO, Hansen ME, Kelleher JK, Stephanopoulos G
(2011) Mol Biosyst 7: 1409-19
MeSH Terms: Animals, Apoptosis, Carcinoma, Hepatocellular, Cell Line, Tumor, Citric Acid Cycle, Fatty Liver, Gas Chromatography-Mass Spectrometry, Glycolysis, Liver Neoplasms, Metabolome, Metabolomics, Oleic Acid, Palmitates, Pentose Phosphate Pathway, Rats, Reactive Oxygen Species, Signal Transduction
Added January 23, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms