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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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Loss of Serotonin Transporter Function Alters ADP-mediated Glycoprotein αIIbβ3 Activation through Dysregulation of the 5-HT2A Receptor.
Oliver KH, Duvernay MT, Hamm HE, Carneiro AM
(2016) J Biol Chem 291: 20210-9
MeSH Terms: Adenosine Diphosphate, Animals, Blood Platelets, Citalopram, Female, Male, Mice, Mice, Knockout, Platelet Glycoprotein GPIIb-IIIa Complex, Receptor, Serotonin, 5-HT2A, Serotonin Plasma Membrane Transport Proteins
Added October 26, 2016
1 Communities
3 Members
0 Resources
11 MeSH Terms
Serotonin transporter and integrin beta 3 genes interact to modulate serotonin uptake in mouse brain.
Whyte A, Jessen T, Varney S, Carneiro AM
(2014) Neurochem Int 73: 122-6
MeSH Terms: Animals, Brain Chemistry, Citalopram, Integrin beta3, Mice, Mice, Knockout, Serotonin, Serotonin Plasma Membrane Transport Proteins, Serotonin Uptake Inhibitors, Synapses, Synaptosomes
Added February 12, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Y95 and E444 interaction required for high-affinity S-citalopram binding in the human serotonin transporter.
Combs S, Kaufmann K, Field JR, Blakely RD, Meiler J
(2011) ACS Chem Neurosci 2: 75-81
MeSH Terms: Animals, Antidepressive Agents, Citalopram, Crystallography, X-Ray, Humans, Protein Binding, Serotonin Plasma Membrane Transport Proteins, Stereoisomerism
Added July 10, 2013
2 Communities
2 Members
0 Resources
8 MeSH Terms
The SSRI citalopram affects fetal thalamic axon responsiveness to netrin-1 in vitro independently of SERT antagonism.
Bonnin A, Zhang L, Blakely RD, Levitt P
(2012) Neuropsychopharmacology 37: 1879-84
MeSH Terms: Animals, Axons, Citalopram, Coculture Techniques, Female, Fetus, Male, Mice, Mice, Inbred C57BL, Mice, Inbred ICR, Mice, Transgenic, Nerve Growth Factors, Netrin-1, Paroxetine, Receptors, sigma, Serotonin, Serotonin Plasma Membrane Transport Proteins, Serotonin Uptake Inhibitors, Thalamus, Tumor Suppressor Proteins
Added July 10, 2013
2 Communities
1 Members
0 Resources
20 MeSH Terms
Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs.
An Z, Moore MC, Winnick JJ, Farmer B, Neal DW, Lautz M, Smith M, Rodewald T, Cherrington AD
(2009) Eur J Pharmacol 607: 251-7
MeSH Terms: Animals, Antidepressive Agents, Second-Generation, Carbon, Citalopram, Diabetes Mellitus, Type 2, Dogs, Glucose, Glucose Clamp Technique, Glycogen, Hyperinsulinism, Infusions, Intravenous, Liver, Portal Vein, Somatostatin, Time Factors
Added June 2, 2014
0 Communities
4 Members
0 Resources
15 MeSH Terms
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF, Newman AH, Blakely RD
(2006) J Biol Chem 281: 2012-23
MeSH Terms: Adrenergic Uptake Inhibitors, Amino Acid Sequence, Animals, Antidepressive Agents, Binding Sites, Binding, Competitive, Blotting, Western, Cadmium, Cell Line, Cell Membrane, Citalopram, Clomipramine, Cocaine, Cysteine, Dopamine Uptake Inhibitors, Fluoxetine, HeLa Cells, Humans, Immunoprecipitation, Isoleucine, Kinetics, LLC-PK1 Cells, Mazindol, Methionine, Mice, Models, Chemical, Molecular Sequence Data, Mutation, N-Methyl-3,4-methylenedioxyamphetamine, Nomifensine, Protein Binding, Protein Structure, Tertiary, Protein Transport, Radiopharmaceuticals, Receptors, Serotonin, Serotonin, Serotonin Uptake Inhibitors, Species Specificity, Stereoisomerism, Substrate Specificity, Tyrosine
Added July 10, 2013
2 Communities
1 Members
0 Resources
41 MeSH Terms
5-Hydroxytryptamine drives apoptosis in biopsylike Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors.
Serafeim A, Grafton G, Chamba A, Gregory CD, Blakely RD, Bowery NG, Barnes NM, Gordon J
(2002) Blood 99: 2545-53
MeSH Terms: Apoptosis, Biopsy, Blotting, Western, Burkitt Lymphoma, Carrier Proteins, Caspases, Cell Survival, Citalopram, DNA Damage, DNA, Neoplasm, Fluoxetine, Humans, Membrane Glycoproteins, Membrane Transport Proteins, Nerve Tissue Proteins, Paroxetine, Serotonin, Serotonin Plasma Membrane Transport Proteins, Serotonin Uptake Inhibitors, Tumor Cells, Cultured
Added July 10, 2013
1 Communities
1 Members
0 Resources
20 MeSH Terms
High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.
Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, Blakely RD
(1998) J Biol Chem 273: 19459-68
MeSH Terms: Animals, Binding Sites, Binding, Competitive, Biological Transport, Carrier Proteins, Citalopram, Drosophila, Drosophila Proteins, HeLa Cells, Humans, Mazindol, Membrane Glycoproteins, Membrane Proteins, Membrane Transport Proteins, Models, Molecular, Molecular Structure, Mutagenesis, Site-Directed, Nerve Tissue Proteins, Recombinant Fusion Proteins, Serotonin, Serotonin Antagonists, Serotonin Plasma Membrane Transport Proteins, Transfection
Added July 10, 2013
1 Communities
1 Members
0 Resources
23 MeSH Terms