Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 7 of 7

Publication Record

Connections

F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials.
Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA
(2017) Clin Cancer Res 23: 3053-3060
MeSH Terms: Adult, Aged, Biomarkers, Pharmacological, Breast Neoplasms, Cinnamates, Dose-Response Relationship, Drug, Estradiol, Estrogen Receptor alpha, Female, Fulvestrant, Humans, Indazoles, Middle Aged, Molecular Imaging, Molecular Targeted Therapy, Positron Emission Tomography Computed Tomography, Receptors, Estrogen, Tamoxifen
Added April 6, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.
Joseph JD, Darimont B, Zhou W, Arrazate A, Young A, Ingalla E, Walter K, Blake RA, Nonomiya J, Guan Z, Kategaya L, Govek SP, Lai AG, Kahraman M, Brigham D, Sensintaffar J, Lu N, Shao G, Qian J, Grillot K, Moon M, Prudente R, Bischoff E, Lee KJ, Bonnefous C, Douglas KL, Julien JD, Nagasawa JY, Aparicio A, Kaufman J, Haley B, Giltnane JM, Wertz IE, Lackner MR, Nannini MA, Sampath D, Schwarz L, Manning HC, Tantawy MN, Arteaga CL, Heyman RA, Rix PJ, Friedman L, Smith ND, Metcalfe C, Hager JH
(2016) Elife 5:
MeSH Terms: Animals, Antineoplastic Agents, Breast Neoplasms, Cell Line, Tumor, Cinnamates, Disease Models, Animal, Heterografts, Humans, Indazoles, Mice, Prospective Studies, Rats, Receptors, Estrogen, Treatment Outcome
Added April 6, 2017
0 Communities
2 Members
0 Resources
14 MeSH Terms
Multitargeting of selected prostanoid receptors provides agents with enhanced anti-inflammatory activity in macrophages.
Wang JW, Woodward DF, Martos JL, Cornell CL, Carling RW, Kingsley PJ, Marnett LJ
(2016) FASEB J 30: 394-404
MeSH Terms: Anti-Inflammatory Agents, Non-Steroidal, Bridged Bicyclo Compounds, Heterocyclic, Cells, Cultured, Cinnamates, Humans, Macrophages, Receptors, Prostaglandin, Receptors, Thromboxane, Substrate Specificity
Added February 22, 2016
0 Communities
2 Members
0 Resources
9 MeSH Terms
A novel channelopathy in pulmonary arterial hypertension.
Ma L, Roman-Campos D, Austin ED, Eyries M, Sampson KS, Soubrier F, Germain M, Trégouët DA, Borczuk A, Rosenzweig EB, Girerd B, Montani D, Humbert M, Loyd JE, Kass RS, Chung WK
(2013) N Engl J Med 369: 351-361
MeSH Terms: Amino Acid Sequence, Channelopathies, Chlorobenzoates, Cinnamates, Exome, Familial Primary Pulmonary Hypertension, Female, Genetic Predisposition to Disease, Heterozygote, Humans, Hypertension, Pulmonary, Lung, Male, Molecular Sequence Data, Mutation, Missense, Nerve Tissue Proteins, Pedigree, Potassium Channels, Tandem Pore Domain, Sequence Analysis, DNA, ortho-Aminobenzoates
Added March 20, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
Comparative study of the active site caging of serine proteases: thrombin and factor Xa.
Thuring JW, Li H, Porter NA
(2002) Biochemistry 41: 2002-13
MeSH Terms: Acylation, Animals, Avidin, Biotin, Catalytic Domain, Cattle, Cinnamates, Factor Xa, Factor Xa Inhibitors, Humans, In Vitro Techniques, Kinetics, Molecular Structure, Photochemistry, Serine Endopeptidases, Serine Proteinase Inhibitors, Thrombin
Added May 29, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties.
Liu G, Huth JR, Olejniczak ET, Mendoza R, DeVries P, Leitza S, Reilly EB, Okasinski GF, Fesik SW, von Geldern TW
(2001) J Med Chem 44: 1202-10
MeSH Terms: Allosteric Regulation, Amides, Animals, Cinnamates, Combinatorial Chemistry Techniques, Intercellular Adhesion Molecule-1, Ligands, Lymphocyte Function-Associated Antigen-1, Magnetic Resonance Spectroscopy, Models, Molecular, Rats, Solubility, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Phospholipid peroxidation in tumor promoter-exposed mouse skin.
Beckman JK, Bagheri F, Ji C, Blair IA, Marnett LJ
(1994) Carcinogenesis 15: 2937-44
MeSH Terms: Aminobenzoates, Animals, Antioxidants, Borohydrides, Calcimycin, Chlorobenzoates, Chromatography, High Pressure Liquid, Cinnamates, Epidermis, Female, Fluocinolone Acetonide, Free Radicals, Gas Chromatography-Mass Spectrometry, Hydrolysis, Linoleic Acids, Linoleic Acids, Conjugated, Lipid Peroxidation, Lipoxygenase Inhibitors, Masoprocol, Mice, Mice, Inbred SENCAR, Phospholipases A, Phospholipases A2, Phospholipids, Pregnatrienes, Stereoisomerism, Tetradecanoylphorbol Acetate, Thiobarbituric Acid Reactive Substances, ortho-Aminobenzoates
Added March 5, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms