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Results: 1 to 10 of 54

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Malformations in the Murine Kidney Caused by Loss of CENP-F Function.
Haley CO, Waters AM, Bader DM
(2019) Anat Rec (Hoboken) 302: 163-170
MeSH Terms: Acute Kidney Injury, Animals, Centromere, Chromosomal Proteins, Non-Histone, Hydronephrosis, Kidney, Kidney Function Tests, Mice, Mice, Knockout, Microfilament Proteins, Tumor Suppressor Proteins
Added January 8, 2019
1 Communities
0 Members
0 Resources
11 MeSH Terms
Loss of CENP-F Results in Dilated Cardiomyopathy with Severe Disruption of Cardiac Myocyte Architecture.
Manalo A, Schroer AK, Fenix AM, Shancer Z, Coogan J, Brolsma T, Burnette DT, Merryman WD, Bader DM
(2018) Sci Rep 8: 7546
MeSH Terms: Animals, Cardiomyopathy, Dilated, Chromosomal Proteins, Non-Histone, Disease Models, Animal, Genetic Association Studies, Genetic Predisposition to Disease, Heart Failure, Humans, Intercellular Junctions, Loss of Function Mutation, Mice, Microfilament Proteins, Microtubules, Myocytes, Cardiac, Polymorphism, Single Nucleotide, Stroke Volume
Added March 27, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities.
Pfaltzgraff ER, Roth GM, Miller PM, Gintzig AG, Ohi R, Bader DM
(2016) Mol Biol Cell 27: 1990-9
MeSH Terms: Animals, Cell Cycle, Centromere, Chromosomal Proteins, Non-Histone, Chromosome Aberrations, Chromosome Segregation, Fibroblasts, Interphase, Kinetochores, Mice, Mice, Knockout, Microfilament Proteins, Microtubules, Mitosis, Protein Binding
Added March 29, 2017
1 Communities
2 Members
0 Resources
15 MeSH Terms
The SUMO deconjugating peptidase Smt4 contributes to the mechanism required for transition from sister chromatid arm cohesion to sister chromatid pericentromere separation.
Stephens AD, Snider CE, Bloom K
(2015) Cell Cycle 14: 2206-18
MeSH Terms: Cell Cycle Proteins, Centromere, Chromatids, Chromosomal Proteins, Non-Histone, Chromosome Segregation, DNA Topoisomerases, Type II, Endopeptidases, Lac Operon, Mitosis, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Spindle Apparatus, Sumoylation
Added January 25, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.
Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, Michailidou K, Bolla MK, Wang Q, Dennis J, Shah M, Perkins BJ, Czene K, Darabi H, Eriksson M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Neven P, Peeters S, Weltens C, Couch FJ, Olson JE, Wang X, Purrington K, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Peto J, dos-Santos-Silva I, Johnson N, Fletcher O, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Schmidt MK, Broeks A, Cornelissen S, Hogervorst FB, Li J, Brand JS, Humphreys K, Guénel P, Truong T, Menegaux F, Sanchez M, Burwinkel B, Marmé F, Yang R, Bugert P, González-Neira A, Benitez J, Pilar Zamora M, Arias Perez JI, Cox A, Cross SS, Reed MW, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, kConFab Investigators, Australian Ovarian Cancer Study Group, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, Kriege M, Koppert LB, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Slettedahl S, Toland AE, Vachon C, Yannoukakos D, Giles GG, Milne RL, McLean C, Fasching PA, Ruebner M, Ekici AB, Beckmann MW, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Ashworth A, Orr N, Schoemaker MJ, Swerdlow A, García-Closas M, Figueroa J, Chanock SJ, Lissowska J, Goldberg MS, Labrèche F, Dumont M, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Brauch H, Brüning T, Ko YD, GENICA Network, Radice P, Peterlongo P, Scuvera G, Fortuzzi S, Bogdanova N, Dörk T, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Devilee P, Tollenaar RA, Seynaeve C, Van Asperen CJ, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Zheng W, Shrubsole MJ, Cai Q, Torres D, Anton-Culver H, Kristensen V, Bacot F, Tessier DC, Vincent D, Luccarini C, Baynes C, Ahmed S, Maranian M, Simard J, Chenevix-Trench G, Hall P, Pharoah PD, Dunning AM, Easton DF, Hamann U
(2015) Carcinogenesis 36: 256-71
MeSH Terms: 3' Untranslated Regions, Aurora Kinase B, Breast Neoplasms, Case-Control Studies, Cell Cycle Proteins, Chromosomal Proteins, Non-Histone, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Inhibitor of Apoptosis Proteins, Polymorphism, Single Nucleotide, Receptors, Estrogen, Risk, Survivin
Added September 28, 2015
0 Communities
2 Members
0 Resources
16 MeSH Terms
The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes.
Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O' Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL
(2015) J Med Genet 52: 147-56
MeSH Terms: Animals, Centrioles, Chromosomal Proteins, Non-Histone, Cilia, Exome, Female, Fetus, Genetics, Medical, HEK293 Cells, High-Throughput Nucleotide Sequencing, Humans, Male, Mice, Microcephaly, Microfilament Proteins, Mutation, NIH 3T3 Cells, Pedigree, Pregnancy, Zebrafish
Added September 28, 2015
1 Communities
1 Members
0 Resources
20 MeSH Terms
SMARCB1 expression in epithelioid sarcoma is regulated by miR-206, miR-381, and miR-671-5p on Both mRNA and protein levels.
Papp G, Krausz T, Stricker TP, Szendrői M, Sápi Z
(2014) Genes Chromosomes Cancer 53: 168-76
MeSH Terms: Chromosomal Proteins, Non-Histone, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Humans, MicroRNAs, RNA Interference, RNA, Messenger, SMARCB1 Protein, Sarcoma, Transcription Factors
Added March 28, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Individual pericentromeres display coordinated motion and stretching in the yeast spindle.
Stephens AD, Snider CE, Haase J, Haggerty RA, Vasquez PA, Forest MG, Bloom K
(2013) J Cell Biol 203: 407-16
MeSH Terms: Adenosine Triphosphatases, Cell Cycle Proteins, Centromere, Chromatids, Chromatin, Chromosomal Proteins, Non-Histone, Chromosome Segregation, DNA-Binding Proteins, Kinesin, Kinetochores, Microtubules, Mitosis, Multiprotein Complexes, Nuclear Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Spindle Apparatus, Stress, Physiological
Added January 25, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Posttranslational modification of CENP-A influences the conformation of centromeric chromatin.
Bailey AO, Panchenko T, Sathyan KM, Petkowski JJ, Pai PJ, Bai DL, Russell DH, Macara IG, Shabanowitz J, Hunt DF, Black BE, Foltz DR
(2013) Proc Natl Acad Sci U S A 110: 11827-32
MeSH Terms: Autoantigens, Cell Cycle Proteins, Cell Line, Centromere, Centromere Protein A, Chromatin, Chromatography, High Pressure Liquid, Chromosomal Proteins, Non-Histone, Epigenesis, Genetic, Guanine Nucleotide Exchange Factors, Humans, Mass Spectrometry, Methylation, Molecular Conformation, Nuclear Proteins, Phosphorylation, Protein Processing, Post-Translational, Ultracentrifugation
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo.
Mathew S, Nguyen M, Wu X, Pal A, Shah VB, Prasad VR, Aiken C, Kalpana GV
(2013) Retrovirology 10: 66
MeSH Terms: Cell Line, Chromosomal Proteins, Non-Histone, DNA-Binding Proteins, HIV Integrase, HIV-1, Host-Pathogen Interactions, Humans, Microscopy, Electron, Transmission, Reverse Transcription, SMARCB1 Protein, Transcription Factors, Virion, Virus Assembly, Virus Integration
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms