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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.
Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network, Thorsson V, Bass AJ, Laird PW
(2018) Cancer Cell 33: 721-735.e8
MeSH Terms: Adenocarcinoma, Aneuploidy, Chromosomal Instability, DNA Methylation, DNA Polymerase II, DNA-Binding Proteins, Epigenesis, Genetic, Female, Gastrointestinal Neoplasms, Gene Regulatory Networks, Heterogeneous-Nuclear Ribonucleoproteins, Humans, Male, Microsatellite Instability, MutL Protein Homolog 1, Mutation, Poly-ADP-Ribose Binding Proteins, Polymorphism, Single Nucleotide, Proto-Oncogene Proteins p21(ras), RNA-Binding Proteins, SOX9 Transcription Factor
Added October 30, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas.
Sun M, Tong P, Kong W, Dong B, Huang Y, Park IY, Zhou L, Liu XD, Ding Z, Zhang X, Bai S, German P, Powell R, Wang Q, Tong X, Tannir NM, Matin SF, Rathmell WK, Fuller GN, McCutcheon IE, Walker CL, Wang J, Jonasch E
(2017) Cancer Res 77: 5313-5326
MeSH Terms: Aneuploidy, Animals, Apoptosis, Carcinoma, Renal Cell, Cell Cycle, Cell Cycle Proteins, Cell Proliferation, Cells, Cultured, Chromosomal Instability, Embryo, Mammalian, Fibroblasts, Hepatocyte Nuclear Factor 1-beta, Humans, Kidney Neoplasms, Mad2 Proteins, Mice, Protein Serine-Threonine Kinases
Added October 30, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.
Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE
(2013) PLoS One 8: e80228
MeSH Terms: ADP-Ribosylation Factors, Animals, Centrosome, Chromosomal Instability, Fibroblasts, Gene Knockout Techniques, Gene Silencing, Humans, Mice, Nuclear Proteins, Nucleophosmin, Oncogene Proteins, Tumor Suppressor Protein p53, rab GTP-Binding Proteins
Added March 17, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.
Lushnikova T, Bouska A, Odvody J, Dupont WD, Eischen CM
(2011) Oncogene 30: 4622-31
MeSH Terms: Aging, Animals, Chromosomal Instability, Gene Expression Regulation, Humans, Mice, Mice, Transgenic, Polyploidy, Precancerous Conditions, Proto-Oncogene Proteins c-mdm2
Added March 5, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
Murine double minute 2: p53-independent roads lead to genome instability or death.
Bouska A, Eischen CM
(2009) Trends Biochem Sci 34: 279-86
MeSH Terms: Animals, Cell Cycle, Cell Death, Chromosomal Instability, DNA Repair, DNA Replication, Gene Expression Regulation, Genome, Mice, Models, Biological, Models, Genetic, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53
Added March 17, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.
Cheng YW, Pincas H, Bacolod MD, Schemmann G, Giardina SF, Huang J, Barral S, Idrees K, Khan SA, Zeng Z, Rosenberg S, Notterman DA, Ott J, Paty P, Barany F
(2008) Clin Cancer Res 14: 6005-13
MeSH Terms: Chromosomal Instability, Chromosome Aberrations, Colorectal Neoplasms, CpG Islands, DNA Methylation, Epigenesis, Genetic, Female, Gene Expression Regulation, Neoplastic, Genome, Human, Humans, Male, Microsatellite Repeats, Mutation, Phenotype, Proto-Oncogene Proteins B-raf
Added March 28, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.
Wang P, Lushnikova T, Odvody J, Greiner TC, Jones SN, Eischen CM
(2008) Oncogene 27: 1590-8
MeSH Terms: Animals, Apoptosis, Blotting, Southern, Blotting, Western, Cell Survival, Chromosomal Instability, Female, Humans, Lymphoma, B-Cell, Male, Mice, Mice, Transgenic, Mutagenesis, Site-Directed, Precursor Cells, B-Lymphoid, Proto-Oncogene Proteins c-mdm2, Proto-Oncogene Proteins c-myc, Survival Rate, Tumor Suppressor Protein p53
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability.
Donahue SL, Lin Q, Cao S, Ruley HE
(2006) Proc Natl Acad Sci U S A 103: 11642-6
MeSH Terms: Animals, Carcinogens, Cell Line, Chromosomal Instability, Genome, Genotype, Humans, Loss of Heterozygosity, Mice, Mutation, Neoplasms, Phenotype, Stem Cells
Added May 29, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms