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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Long non-coding RNA enhances chondrogenesis via suppression of the interferon type II signaling pathway.
Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F
(2020) Elife 9:
MeSH Terms: Binding Sites, Cell Differentiation, Cells, Cultured, Chondrocytes, Chondrogenesis, Extracellular Matrix, Gene Editing, Gene Expression Profiling, Gene Expression Regulation, Developmental, Gene Regulatory Networks, Humans, Immunohistochemistry, Interferon-gamma, Mesenchymal Stem Cells, Protein Binding, RNA, Long Noncoding, Signal Transduction
Added March 16, 2021
0 Communities
1 Members
0 Resources
17 MeSH Terms
Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds.
Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F
(2018) Tissue Eng Part A 24: 1531-1544
MeSH Terms: Adult, Cells, Cultured, Chondrogenesis, Collagen Type II, Core Binding Factor Alpha 1 Subunit, Extracellular Matrix, Gene Knockdown Techniques, Genetic Engineering, Glycosaminoglycans, Humans, Mesenchymal Stem Cells, Minerals, Osteogenesis, Smad3 Protein, Tissue Engineering, Tissue Scaffolds, Transforming Growth Factor beta3
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development.
Kara N, Wei C, Commanday AC, Patton JG
(2017) Dev Biol 429: 321-334
MeSH Terms: Animal Fins, Animals, Branchial Region, Cartilage, Cell Differentiation, Cell Proliferation, Cell Survival, Chondrogenesis, Embryo, Nonmammalian, Focal Adhesion Protein-Tyrosine Kinases, Gene Expression Regulation, Developmental, Gene Knockdown Techniques, MicroRNAs, Morphogenesis, Neural Crest, Zebrafish
Added August 4, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.
Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD
(2017) Tissue Eng Part A 23: 738-749
MeSH Terms: Adipose Tissue, Cell Differentiation, Cell Survival, Chondrogenesis, Clustered Regularly Interspaced Short Palindromic Repeats, DNA, Epigenesis, Genetic, Extracellular Matrix, Gene Editing, Glycosaminoglycans, HEK293 Cells, Humans, Immunomodulation, Inflammation, Lentivirus, NF-kappa B, Receptors, Cytokine, Receptors, Tumor Necrosis Factor, Stem Cells, Tissue Engineering, Transduction, Genetic
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues.
Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F
(2017) Arthritis Rheumatol 69: 1111-1121
MeSH Terms: Animals, CRISPR-Cas Systems, Cartilage, Chondrocytes, Chondrogenesis, Flow Cytometry, Gene Deletion, Gene Editing, Gene Expression, Gene Expression Regulation, Induced Pluripotent Stem Cells, Inflammation, Interleukin-1, Mice, NF-kappa B, Receptors, Interleukin-1, Tissue Engineering
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.
Karolak MR, Yang X, Elefteriou F
(2015) Hum Mol Genet 24: 2552-64
MeSH Terms: Animals, Chondrocytes, Chondrogenesis, Collagen Type II, Female, Gene Expression, Gene Knockout Techniques, Growth Plate, Hypertrophy, Male, Mice, Mice, Knockout, Neurofibromin 1, Osteoclasts, Osteogenesis, Phenotype, Phenylurea Compounds, Protein Transport, Pyrimidines, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 3, Signal Transduction
Added February 19, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells.
Diekman BO, Thakore PI, O'Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F
(2015) Tissue Eng Part A 21: 1261-74
MeSH Terms: Animals, Bromodeoxyuridine, Cartilage, Cell Differentiation, Cell Proliferation, Cells, Cultured, Chondrogenesis, Collagen, Collagen Type I, Collagen Type X, Cyclin-Dependent Kinase Inhibitor p21, DNA, Gene Expression Regulation, Gene Knockdown Techniques, Glycosaminoglycans, Immunohistochemistry, Induced Pluripotent Stem Cells, Mice
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Tissue-engineered cartilage with inducible and tunable immunomodulatory properties.
Glass KA, Link JM, Brunger JM, Moutos FT, Gersbach CA, Guilak F
(2014) Biomaterials 35: 5921-31
MeSH Terms: Cartilage, Cells, Cultured, Chondrogenesis, Genetic Therapy, Humans, Interleukin 1 Receptor Antagonist Protein, Interleukin-1, Mesenchymal Stem Cells, Osteoarthritis, Tissue Engineering, Tissue Scaffolds, Up-Regulation
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.
Brunger JM, Huynh NP, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F
(2014) Proc Natl Acad Sci U S A 111: E798-806
MeSH Terms: Analysis of Variance, Biomechanical Phenomena, Cell Differentiation, Chondrogenesis, DNA Primers, Extracellular Matrix, Flow Cytometry, Gene Transfer Techniques, Humans, Immunohistochemistry, Lentivirus, Mesenchymal Stem Cells, Microscopy, Electron, Scanning, Microscopy, Fluorescence, Polyesters, Polylysine, Regenerative Medicine, Tissue Engineering, Tissue Scaffolds, Transduction, Genetic, Transforming Growth Factor beta3
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Ono K, Karolak MR, Ndong Jde L, Wang W, Yang X, Elefteriou F
(2013) Hum Mol Genet 22: 3048-62
MeSH Terms: Animals, Apoptosis, Cell Proliferation, Chondrocytes, Chondrogenesis, Extracellular Signal-Regulated MAP Kinases, Gene Expression, Growth Plate, Mice, Knockout, Neurofibromin 1, Osteogenesis, Receptors, Fibroblast Growth Factor, Signal Transduction
Added November 14, 2013
1 Communities
3 Members
0 Resources
13 MeSH Terms