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Results: 1 to 3 of 3

Publication Record


Effect of psychotropic drug treatment on sterol metabolism.
Korade Ž, Liu W, Warren EB, Armstrong K, Porter NA, Konradi C
(2017) Schizophr Res 187: 74-81
MeSH Terms: Adult, Animals, Antidepressive Agents, Antipsychotic Agents, Body Mass Index, Cholestadienols, Clozapine, Dehydrocholesterols, Female, Haloperidol, Humans, Lipid Metabolism, Male, Mental Disorders, Psychiatric Status Rating Scales, Random Allocation, Rats, Sprague-Dawley, Weight Gain
Added April 6, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design.
Hargrove TY, Friggeri L, Wawrzak Z, Sivakumaran S, Yazlovitskaya EM, Hiebert SW, Guengerich FP, Waterman MR, Lepesheva GI
(2016) J Lipid Res 57: 1552-63
MeSH Terms: 14-alpha Demethylase Inhibitors, Antifungal Agents, Antineoplastic Agents, Antiprotozoal Agents, Catalytic Domain, Cell Line, Tumor, Cholestadienols, Crystallography, X-Ray, Drug Design, Drug Screening Assays, Antitumor, Humans, Hydrogen Bonding, Lanosterol, Models, Molecular, Protein Binding, Protein Conformation, alpha-Helical, Sterol 14-Demethylase
Added April 6, 2017
0 Communities
4 Members
0 Resources
17 MeSH Terms
CYP51 from Trypanosoma brucei is obtusifoliol-specific.
Lepesheva GI, Nes WD, Zhou W, Hill GC, Waterman MR
(2004) Biochemistry 43: 10789-99
MeSH Terms: Amino Acid Sequence, Animals, Cholestadienols, Cloning, Molecular, Cytochrome P-450 Enzyme System, Isoenzymes, Oxidoreductases, Protozoan Proteins, Rats, Sequence Alignment, Sterol 14-Demethylase, Substrate Specificity, Trypanosoma brucei brucei
Added February 12, 2015
0 Communities
2 Members
0 Resources
13 MeSH Terms