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Results: 1 to 5 of 5

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Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
Yamazaki H, Gillam EM, Dong MS, Johnson WW, Guengerich FP, Shimada T
(1997) Arch Biochem Biophys 342: 329-37
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Chlorzoxazone, Cytochrome P-450 CYP2C9, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Cytochromes b5, Escherichia coli, Ethanolamines, Humans, Hydroxylation, Mixed Function Oxygenases, Mutation, NADP, Nifedipine, Oxidation-Reduction, Phospholipids, Recombinant Proteins, Testosterone, Theophylline, Tolbutamide, Warfarin
Added May 26, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
Kim RB, Yamazaki H, Chiba K, O'Shea D, Mimura M, Guengerich FP, Ishizaki T, Shimada T, Wilkinson GR
(1996) J Pharmacol Exp Ther 279: 4-11
MeSH Terms: Adolescent, Adult, Asian Continental Ancestry Group, Chlorzoxazone, Cytochrome P-450 CYP2E1, European Continental Ancestry Group, Humans, Japan, Male, Polymorphism, Restriction Fragment Length
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.
Gillam EM, Guo Z, Guengerich FP
(1994) Arch Biochem Biophys 312: 59-66
MeSH Terms: Base Sequence, Catalysis, Chlorzoxazone, Cloning, Molecular, Cytochrome P-450 CYP2E1, Cytochrome P-450 Enzyme System, Escherichia coli, Humans, Hydroxylation, Molecular Sequence Data, Mutation, Nucleic Acid Conformation, Oxidoreductases, N-Demethylating, RNA, Messenger, Recombinant Proteins, Sequence Analysis, Spectrophotometry
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation.
Yamazaki H, Guo Z, Guengerich FP
(1995) Drug Metab Dispos 23: 438-40
MeSH Terms: Chlorzoxazone, Cytochrome P-450 CYP2E1, Cytochrome P-450 Enzyme System, Humans, Hydroxylation, Oxidoreductases, N-Demethylating, Substrate Specificity
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Effects of zoxazolamine and related centrally acting muscle relaxants on nigrostriatal dopaminergic neurons.
Matthews RT, McMillen BA, Speciale SG, Jarrah H, Shore PA, Sanghera MK, Shepard PD, German DC
(1984) Brain Res Bull 12: 479-86
MeSH Terms: Animals, Chlorzoxazone, Corpus Striatum, Dopamine, Drug Interactions, Female, Haloperidol, Mephenesin, Muscle Relaxants, Central, Rats, Rats, Inbred Strains, Substantia Nigra, Zoxazolamine
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms