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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 79

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Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.
Mavrovic M, Uvarov P, Delpire E, Vutskits L, Kaila K, Puskarjov M
(2020) EMBO Rep 21: e48880
MeSH Terms: Apoptosis, Chlorides, Epilepsy, Humans, Neurons, Symporters
Added March 18, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Perry JSA, Morioka S, Medina CB, Iker Etchegaray J, Barron B, Raymond MH, Lucas CD, Onengut-Gumuscu S, Delpire E, Ravichandran KS
(2019) Nat Cell Biol 21: 1532-1543
MeSH Terms: Animals, Apoptosis, Biological Transport, Cell Line, Cell Line, Tumor, Chlorides, Humans, Inflammation, Jurkat Cells, Mice, Mice, Inbred C57BL, Oxidative Stress, Phagocytes, Phagocytosis, Signal Transduction, Sodium-Potassium-Chloride Symporters, Transcription, Genetic
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Cryo-EM structures of NKCC1 and hKCC1: a new milestone in the physiology of cation-chloride cotransporters.
Delpire E, Guo J
(2020) Am J Physiol Cell Physiol 318: C225-C237
MeSH Terms: Amino Acid Sequence, Animals, Cations, Chlorides, Cryoelectron Microscopy, Humans, Solute Carrier Family 12, Member 2, Symporters
Added March 18, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Watanabe M, Zhang J, Mansuri MS, Duan J, Karimy JK, Delpire E, Alper SL, Lifton RP, Fukuda A, Kahle KT
(2019) Sci Signal 12:
MeSH Terms: Animals, Animals, Newborn, Binding Sites, Cells, Cultured, Central Nervous System, Chlorides, Gene Expression Regulation, Developmental, Male, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Neurons, Phosphorylation, Signal Transduction, Symporters, gamma-Aminobutyric Acid
Added March 18, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Loss of MYO5B Leads to Reductions in Na Absorption With Maintenance of CFTR-Dependent Cl Secretion in Enterocytes.
Engevik AC, Kaji I, Engevik MA, Meyer AR, Weis VG, Goldstein A, Hess MW, Müller T, Koepsell H, Dudeja PK, Tyska M, Huber LA, Shub MD, Ameen N, Goldenring JR
(2018) Gastroenterology 155: 1883-1897.e10
MeSH Terms: Animals, Aquaporins, Chlorides, Cystic Fibrosis Transmembrane Conductance Regulator, Duodenum, Enterocytes, Gene Silencing, Humans, Intestinal Mucosa, Intestines, Malabsorption Syndromes, Mice, Mice, Knockout, Microvilli, Mucolipidoses, Myosin Type V, Protein Transport, Sodium-Glucose Transporter 1, Sodium-Hydrogen Exchanger 3, Sodium-Hydrogen Exchangers, Sucrase-Isomaltase Complex, Tamoxifen
Added February 7, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects.
Bowerman M, Salsac C, Bernard V, Soulard C, Dionne A, Coque E, Benlefki S, Hince P, Dion PA, Butler-Browne G, Camu W, Bouchard JP, Delpire E, Rouleau GA, Raoul C, Scamps F
(2017) Neurobiol Dis 106: 35-48
MeSH Terms: Agenesis of Corpus Callosum, Animals, Carbamazepine, Cells, Cultured, Chlorides, Disease Models, Animal, Mice, Inbred C57BL, Mice, Transgenic, Motor Neurons, Neuromuscular Junction, Neurotransmitter Agents, Peripheral Nervous System Diseases, Presynaptic Terminals, Sodium-Potassium-Exchanging ATPase, Spinal Cord, Symporters, Synaptic Transmission
Added April 3, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.
Glykys J, Dzhala V, Egawa K, Kahle KT, Delpire E, Staley K
(2017) Trends Neurosci 40: 276-294
MeSH Terms: Animals, Brain Edema, Brain Injuries, Traumatic, Chlorides, Extracellular Matrix, Humans, Neurons, Seizures, Symporters
Added May 3, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
CaMKII-mediated phosphorylation of GluN2B regulates recombinant NMDA receptor currents in a chloride-dependent manner.
Tavalin SJ, Colbran RJ
(2017) Mol Cell Neurosci 79: 45-52
MeSH Terms: Action Potentials, Calcium Signaling, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Chlorides, HEK293 Cells, Humans, Phosphorylation, Protein Binding, Protein Processing, Post-Translational, Receptors, N-Methyl-D-Aspartate
Added April 26, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
A patient with multisystem dysfunction carries a truncation mutation in human , the gene encoding the Na-K-2Cl cotransporter, NKCC1.
Delpire E, Wolfe L, Flores B, Koumangoye R, Schornak CC, Omer S, Pusey B, Lau C, Markello T, Adams DR
(2016) Cold Spring Harb Mol Case Stud 2: a001289
MeSH Terms: Adolescent, Alleles, Carrier Proteins, Cell Membrane, Chlorides, Female, Fibroblasts, Humans, Mutation, Sequence Deletion, Sodium, Sodium, Dietary, Sodium-Potassium-Chloride Symporters, Solute Carrier Family 12, Member 2, Whole Exome Sequencing
Added April 26, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
The Response of Acinetobacter baumannii to Zinc Starvation.
Nairn BL, Lonergan ZR, Wang J, Braymer JJ, Zhang Y, Calcutt MW, Lisher JP, Gilston BA, Chazin WJ, de Crécy-Lagard V, Giedroc DP, Skaar EP
(2016) Cell Host Microbe 19: 826-36
MeSH Terms: Acinetobacter Infections, Acinetobacter baumannii, Animals, Bacterial Proteins, Chlorides, GTP Phosphohydrolases, Gene Expression Regulation, Bacterial, Genes, Bacterial, Histidine, Histidine Ammonia-Lyase, Metallochaperones, Mice, Mice, Inbred C57BL, Mutation, Zinc, Zinc Compounds
Added April 8, 2017
0 Communities
2 Members
0 Resources
16 MeSH Terms