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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 9 of 9

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Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach.
Burclaff J, Osaki LH, Liu D, Goldenring JR, Mills JC
(2017) Gastroenterology 152: 762-766.e7
MeSH Terms: Animals, Apoptosis, Atrophy, Azetidines, Cell Proliferation, Cellular Reprogramming, Chief Cells, Gastric, Diphtheria Toxin, Heparin-binding EGF-like Growth Factor, Intercellular Signaling Peptides and Proteins, Intrinsic Factor, Metaplasia, Mice, Parietal Cells, Gastric, Peptides, Piperazines, Plant Lectins, Stomach, Tamoxifen
Added April 18, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Maturity and age influence chief cell ability to transdifferentiate into metaplasia.
Weis VG, Petersen CP, Weis JA, Meyer AR, Choi E, Mills JC, Goldenring JR
(2017) Am J Physiol Gastrointest Liver Physiol 312: G67-G76
MeSH Terms: Age Factors, Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Lineage, Cell Proliferation, Cell Transdifferentiation, Chief Cells, Gastric, Gastric Mucosa, Intercellular Signaling Peptides and Proteins, Metaplasia, Mice, Mice, Knockout, Parietal Cells, Gastric, Peptides, Stomach
Added April 18, 2017
0 Communities
2 Members
0 Resources
15 MeSH Terms
Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions.
Choi E, Hendley AM, Bailey JM, Leach SD, Goldenring JR
(2016) Gastroenterology 150: 918-30.e13
MeSH Terms: Animals, Anticarcinogenic Agents, Benzimidazoles, Cell Differentiation, Cell Lineage, Cell Proliferation, Cell Transformation, Neoplastic, Chief Cells, Gastric, Disease Progression, Female, Gene Expression Regulation, Neoplastic, Genes, ras, Genetic Predisposition to Disease, Humans, Macrophages, Male, Metaplasia, Mice, Inbred C57BL, Mice, Transgenic, Mitogen-Activated Protein Kinase Kinases, Mutation, Phenotype, Protein Kinase Inhibitors, Signal Transduction, Stomach Neoplasms, Time Factors, Transcriptional Activation
Added March 28, 2016
0 Communities
2 Members
0 Resources
27 MeSH Terms
Identification of alanyl aminopeptidase (CD13) as a surface marker for isolation of mature gastric zymogenic chief cells.
Moore BD, Jin RU, Osaki L, Romero-Gallo J, Noto J, Peek RM, Mills JC
(2015) Am J Physiol Gastrointest Liver Physiol 309: G955-64
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Biomarkers, CD13 Antigens, Carrier Proteins, Cell Separation, Cells, Cultured, Chief Cells, Gastric, Female, Humans, Male, Metaplasia, Mice, Inbred C57BL, Mice, Knockout, Phenotype, Stomach
Added February 5, 2016
0 Communities
2 Members
0 Resources
16 MeSH Terms
Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.
Weis VG, Petersen CP, Mills JC, Tuma PL, Whitehead RH, Goldenring JR
(2014) Am J Physiol Gastrointest Liver Physiol 307: G777-92
MeSH Terms: Animals, Biomarkers, Cells, Cultured, Chief Cells, Gastric, Gastric Mucosa, Intercellular Signaling Peptides and Proteins, Metaplasia, Mice, Myelin and Lymphocyte-Associated Proteolipid Proteins, Nuclear Proteins, Pepsinogen C, Peptides, Proteins, Repressor Proteins, Stomach, Ubiquitin-Protein Ligase Complexes, WAP Four-Disulfide Core Domain Protein 2, rab3 GTP-Binding Proteins
Added February 12, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation.
Capoccia BJ, Jin RU, Kong YY, Peek RM, Fassan M, Rugge M, Mills JC
(2013) J Clin Invest 123: 1475-91
MeSH Terms: Adenocarcinoma, Animals, Apoptosis Regulatory Proteins, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, Calcium-Calmodulin-Dependent Protein Kinases, Cell Differentiation, Cell Enlargement, Cell Polarity, Chief Cells, Gastric, Conserved Sequence, Death-Associated Protein Kinases, Humans, Intestinal Neoplasms, Metaplasia, Mice, Mice, Knockout, Microtubules, Protein Transport, Stomach, Tamoxifen, Ubiquitin-Protein Ligases
Added September 3, 2013
0 Communities
2 Members
0 Resources
22 MeSH Terms
Mature chief cells are cryptic progenitors for metaplasia in the stomach.
Nam KT, Lee HJ, Sousa JF, Weis VG, O'Neal RL, Finke PE, Romero-Gallo J, Shi G, Mills JC, Peek RM, Konieczny SF, Goldenring JR
(2010) Gastroenterology 139: 2028-2037.e9
MeSH Terms: Acute Disease, Animals, Cell Differentiation, Cell Division, Cell Lineage, Chief Cells, Gastric, Chronic Disease, Disease Models, Animal, Gastritis, Helicobacter Infections, Helicobacter felis, Intercellular Signaling Peptides and Proteins, Lac Operon, Metaplasia, Mice, Mice, Inbred C57BL, Mice, Transgenic, Parietal Cells, Gastric, Peptides, Precancerous Conditions, Stem Cells, Stomach Neoplasms
Added October 7, 2013
1 Communities
2 Members
0 Resources
22 MeSH Terms
Altered gastric chief cell lineage differentiation in histamine-deficient mice.
Nozaki K, Weis V, Wang TC, Falus A, Goldenring JR
(2009) Am J Physiol Gastrointest Liver Physiol 296: G1211-20
MeSH Terms: Age Factors, Animals, Azetidines, Basic Helix-Loop-Helix Transcription Factors, Cell Count, Cell Differentiation, Chief Cells, Gastric, Chromogranin A, Enterochromaffin-like Cells, Enzyme Inhibitors, Gastric Fundus, Gastric Mucosa, Gastrins, Histamine, Histidine Decarboxylase, Hyperplasia, Hypertrophy, Intrinsic Factor, Metaplasia, Mice, Mice, Inbred BALB C, Mice, Knockout, Mucins, Muscle Proteins, N-Acetylglucosaminyltransferases, Parietal Cells, Gastric, Peptides, Piperazines, Trefoil Factor-2
Added October 7, 2013
1 Communities
1 Members
0 Resources
29 MeSH Terms
A molecular signature of gastric metaplasia arising in response to acute parietal cell loss.
Nozaki K, Ogawa M, Williams JA, Lafleur BJ, Ng V, Drapkin RI, Mills JC, Konieczny SF, Nomura S, Goldenring JR
(2008) Gastroenterology 134: 511-22
MeSH Terms: Animals, Atrophy, Basic Helix-Loop-Helix Transcription Factors, Carrier Proteins, Cell Cycle Proteins, Cell Transformation, Neoplastic, Chief Cells, Gastric, DNA-Binding Proteins, Epididymal Secretory Proteins, Fetal Proteins, Gastric Fundus, Gastric Mucosa, Gastrins, Humans, Intercellular Signaling Peptides and Proteins, Intrinsic Factor, Metaplasia, Mice, Mice, Inbred C57BL, Mice, Knockout, Microtubule-Associated Proteins, Minichromosome Maintenance Complex Component 3, Mucins, Muscle Proteins, Nuclear Proteins, Parietal Cells, Gastric, Peptides, Precancerous Conditions, Stomach Neoplasms, Trefoil Factor-2, beta-Defensins
Added October 7, 2013
1 Communities
2 Members
0 Resources
31 MeSH Terms