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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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Dual drug delivery of tamoxifen and quercetin: Regulated metabolism for anticancer treatment with nanosponges.
Lockhart JN, Stevens DM, Beezer DB, Kravitz A, Harth E
(2015) J Control Release 220: 751-7
MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, Biological Availability, Biotransformation, Breast Neoplasms, Cell Line, Tumor, Cell Survival, Chemistry, Pharmaceutical, Cross-Linking Reagents, Cytochrome P-450 CYP3A, Delayed-Action Preparations, Dose-Response Relationship, Drug, Drug Carriers, Drug Stability, Female, Gastric Juice, Glucuronosyltransferase, Intestinal Secretions, Kinetics, Mice, Nanomedicine, Nanoparticles, Particle Size, Polyesters, Quercetin, Solubility, Tamoxifen
Added February 15, 2016
0 Communities
1 Members
0 Resources
27 MeSH Terms
Fragment-based screening of the bromodomain of ATAD2.
Harner MJ, Chauder BA, Phan J, Fesik SW
(2014) J Med Chem 57: 9687-92
MeSH Terms: ATPases Associated with Diverse Cellular Activities, Adenosine Triphosphatases, Antineoplastic Agents, Binding Sites, Chemistry, Pharmaceutical, Crystallography, X-Ray, DNA-Binding Proteins, Humans, Kinetics, Ligands, Magnetic Resonance Spectroscopy, Molecular Conformation, Neoplasms, Protein Structure, Tertiary
Added February 12, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Biologic comparison of inhaled insulin formulations: Exuberaâ„¢ and novel spray-dried engineered particles of dextran-10.
Kuehl PJ, Cherrington A, Dobry DE, Edgerton D, Friesen DT, Hobbs C, Leach CL, Murri B, Neal D, Lyon DK, Vodak DT, Reed MD
(2014) AAPS PharmSciTech 15: 1545-50
MeSH Terms: Administration, Inhalation, Aerosols, Animals, Area Under Curve, Blood Glucose, Chemistry, Pharmaceutical, Cross-Over Studies, Dextrans, Dogs, Drug Carriers, Female, Hypoglycemic Agents, Insulin, Metabolic Clearance Rate, Particle Size, Powders, Technology, Pharmaceutical
Added February 12, 2015
0 Communities
2 Members
0 Resources
17 MeSH Terms
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2.
Duggan KC, Hermanson DJ, Musee J, Prusakiewicz JJ, Scheib JL, Carter BD, Banerjee S, Oates JA, Marnett LJ
(2011) Nat Chem Biol 7: 803-9
MeSH Terms: Arachidonic Acid, Arachidonic Acids, Cannabinoid Receptor Modulators, Catalytic Domain, Chemistry, Pharmaceutical, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Endocannabinoids, Glycerides, Models, Molecular, Oxidation-Reduction, Protein Binding, Protein Conformation, Substrate Specificity
Added March 5, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
A phase I study of subcutaneously administered aflibercept (VEGF trap) in a new formulation in patients with advanced solid tumors.
Wang-Gillam A, Tew WP, Rothenberg ML, Dupont J, Cooper W, Sternas L, Buzenet G, Sosman JA, Spriggs DR, Lockhart AC
(2012) Invest New Drugs 30: 1958-61
MeSH Terms: Adult, Aged, Angiogenesis Inhibitors, Antineoplastic Agents, Chemistry, Pharmaceutical, Cohort Studies, Female, Humans, Male, Middle Aged, Neoplasms, Neovascularization, Pathologic, Receptors, Vascular Endothelial Growth Factor, Recombinant Fusion Proteins, Vascular Endothelial Growth Factor A
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Essence of affinity and specificity of peanut agglutinin-immobilized fluorescent nanospheres with surface poly(N-vinylacetamide) chains for colorectal cancer.
Sakuma S, Higashino H, Oshitani H, Masaoka Y, Kataoka M, Yamashita S, Hiwatari K, Tachikawa H, Kimura R, Nakamura K, Kumagai H, Gore JC, Pham W
(2011) Eur J Pharm Biopharm 79: 537-43
MeSH Terms: Acetamides, Animals, Antigens, Tumor-Associated, Carbohydrate, Cecum, Chemistry, Pharmaceutical, Colonoscopy, Colorectal Neoplasms, Contrast Media, Female, Fluorescent Dyes, HT29 Cells, Humans, Intestinal Mucosa, Mice, Mice, SCID, Microscopy, Fluorescence, Nanospheres, Neoplasm Transplantation, Peanut Agglutinin, Polyvinyls, Surface Properties
Added May 27, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Investigation of different formulations for drug delivery through the nail plate.
Vejnovic I, Simmler L, Betz G
(2010) Int J Pharm 386: 185-94
MeSH Terms: Acetylcysteine, Administration, Topical, Boric Acids, Cadaver, Caffeine, Chemistry, Pharmaceutical, Dimethyl Sulfoxide, Dioctyl Sulfosuccinic Acid, Drug Carriers, Ethanol, Female, Fungal Proteins, Humans, Male, Methanol, Nails, Permeability, Pharmaceutic Aids, Technology, Pharmaceutical, Urea, Water
Added August 3, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Intratumoral delivery of Paclitaxel in solid tumor from biodegradable hyaluronan nanoparticle formulations.
Al-Ghananeem AM, Malkawi AH, Muammer YM, Balko JM, Black EP, Mourad W, Romond E
(2009) AAPS PharmSciTech 10: 410-7
MeSH Terms: 9,10-Dimethyl-1,2-benzanthracene, Animals, Antineoplastic Agents, Phytogenic, Chemistry, Pharmaceutical, Female, Hyaluronic Acid, Mammary Neoplasms, Experimental, Nanoparticles, Paclitaxel, Rats, Rats, Sprague-Dawley, Solubility
Added March 10, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Introduction: Human metabolites in safety testing (MIST) issue.
Guengerich FP
(2009) Chem Res Toxicol 22: 237-8
MeSH Terms: Animals, Chemistry, Pharmaceutical, Drug Evaluation, Preclinical, Drug-Related Side Effects and Adverse Reactions, Guidelines as Topic, Humans, Metabolic Networks and Pathways, Mice, Mice, Transgenic, Models, Animal, Pharmaceutical Preparations, Toxicity Tests
Added March 26, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy.
Thapa P, Zhang G, Xia C, Gelbard A, Overwijk WW, Liu C, Hwu P, Chang DZ, Courtney A, Sastry JK, Wang PG, Li C, Zhou D
(2009) Vaccine 27: 3484-8
MeSH Terms: Adjuvants, Immunologic, Animals, Chemistry, Pharmaceutical, Dendritic Cells, Galactosylceramides, Immune Tolerance, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Nanoparticles, Natural Killer T-Cells
Added April 11, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms