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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 37

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miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44.
Sun L, Fang Y, Wang X, Han Y, Du F, Li C, Hu H, Liu H, Liu Q, Wang J, Liang J, Chen P, Yang H, Nie Y, Wu K, Fan D, Coffey RJ, Lu Y, Zhao X, Wang X
(2019) Theranostics 9: 8409-8425
MeSH Terms: Caco-2 Cells, Cetuximab, Colorectal Neoplasms, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, HCT116 Cells, Humans, Hyaluronan Receptors, In Vitro Techniques, MicroRNAs, NFI Transcription Factors, Neoplasm Metastasis, Signal Transduction
Added March 3, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling.
Lu Y, Zhao X, Liu Q, Li C, Graves-Deal R, Cao Z, Singh B, Franklin JL, Wang J, Hu H, Wei T, Yang M, Yeatman TJ, Lee E, Saito-Diaz K, Hinger S, Patton JG, Chung CH, Emmrich S, Klusmann JH, Fan D, Coffey RJ
(2017) Nat Med 23: 1331-1341
MeSH Terms: Antineoplastic Agents, Immunological, Cell Line, Tumor, Cetuximab, Disease Progression, Drug Resistance, Neoplasm, Epigenesis, Genetic, GATA6 Transcription Factor, Humans, MicroRNAs, RNA, Long Noncoding, Signal Transduction, Wnt Proteins, beta Catenin
Added April 3, 2018
0 Communities
2 Members
0 Resources
MeSH Terms
Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer.
Li C, Singh B, Graves-Deal R, Ma H, Starchenko A, Fry WH, Lu Y, Wang Y, Bogatcheva G, Khan MP, Milne GL, Zhao S, Ayers GD, Li N, Hu H, Washington MK, Yeatman TJ, McDonald OG, Liu Q, Coffey RJ
(2017) Proc Natl Acad Sci U S A 114: E2852-E2861
MeSH Terms: Animals, Antineoplastic Agents, Immunological, Cell Culture Techniques, Cell Line, Tumor, Cetuximab, Colorectal Neoplasms, Crizotinib, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Humans, Hydroxyprostaglandin Dehydrogenases, Mice, Phosphorylation, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyrazoles, Pyridines, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Tissue Array Analysis, Versicans, Xenograft Model Antitumor Assays
Added May 3, 2017
0 Communities
3 Members
0 Resources
22 MeSH Terms
In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.
Shah AT, Diggins KE, Walsh AJ, Irish JM, Skala MC
(2015) Neoplasia 17: 862-870
MeSH Terms: Antineoplastic Agents, Cell Line, Tumor, Cell Proliferation, Cetuximab, Cisplatin, Flavin-Adenine Dinucleotide, Humans, Microscopy, Fluorescence, Multiphoton, NADP, Neoplasms, Oxidation-Reduction, Single-Cell Analysis, Time Factors, Tumor Burden, Xenograft Model Antitumor Assays
Added December 24, 2015
2 Communities
3 Members
0 Resources
15 MeSH Terms
[(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.
McKinley ET, Watchmaker JM, Chakravarthy AB, Meyerhardt JA, Engelman JA, Walker RC, Washington MK, Coffey RJ, Manning HC
(2015) Ann Nucl Med 29: 535-42
MeSH Terms: Adult, Antineoplastic Agents, Cetuximab, Chemoradiotherapy, Dideoxynucleosides, Female, Follow-Up Studies, Humans, Immunohistochemistry, Male, Middle Aged, Multimodal Imaging, Neoadjuvant Therapy, Pilot Projects, Positron-Emission Tomography, Proto-Oncogene Proteins p21(ras), Radiopharmaceuticals, Rectal Neoplasms, Tomography, X-Ray Computed, Treatment Outcome
Added July 28, 2015
0 Communities
3 Members
0 Resources
20 MeSH Terms
A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma.
Gilbert J, Schell MJ, Zhao X, Murphy B, Tanvetyanon T, Leon ME, Neil Hayes D, Haigentz M, Saba N, Nieva J, Bishop J, Sidransky D, Ravi R, Bedi A, Chung CH
(2015) Oral Oncol 51: 376-82
MeSH Terms: Adult, Aged, Antineoplastic Agents, Carcinoma, Squamous Cell, Cetuximab, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Neoplasm Metastasis, Niacinamide, Phenylurea Compounds, Recurrence, Sorafenib
Added February 17, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Annotation of human cancers with EGFR signaling-associated protein complexes using proximity ligation assays.
Smith MA, Hall R, Fisher K, Haake SM, Khalil F, Schabath MB, Vuaroqueaux V, Fiebig HH, Altiok S, Chen YA, Haura EB
(2015) Sci Signal 8: ra4
MeSH Terms: Animals, Antibodies, Monoclonal, Humanized, Biomarkers, Tumor, Cell Line, Tumor, Cetuximab, ErbB Receptors, GRB2 Adaptor Protein, Heterografts, Humans, Immunoassay, Lung Neoplasms, Mice, Multiprotein Complexes, Protein Interaction Mapping, Signal Transduction
Added April 18, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms
Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer.
Meador CB, Jin H, de Stanchina E, Nebhan CA, Pirazzoli V, Wang L, Lu P, Vuong H, Hutchinson KE, Jia P, Chen X, Eisenberg R, Ladanyi M, Politi K, Zhao Z, Lovly CM, Cross DA, Pao W
(2015) Mol Cancer Ther 14: 542-52
MeSH Terms: Acrylamides, Afatinib, Aged, Aniline Compounds, Animals, Antibodies, Monoclonal, Humanized, Cell Line, Tumor, Cell Proliferation, Cetuximab, Drug Resistance, Neoplasm, ErbB Receptors, Humans, Lung Neoplasms, Male, Mice, Nude, Molecular Targeted Therapy, Mutation, Quinazolines
Added February 13, 2015
0 Communities
2 Members
0 Resources
18 MeSH Terms
3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.
McKinley ET, Zhao P, Coffey RJ, Washington MK, Manning HC
(2014) PLoS One 9: e108193
MeSH Terms: Animals, Antineoplastic Agents, Cell Line, Tumor, Cetuximab, Colorectal Neoplasms, Mice, Mice, Nude, Phosphatidylinositol 3-Kinases, Positron-Emission Tomography, TOR Serine-Threonine Kinases
Added January 23, 2015
0 Communities
3 Members
0 Resources
10 MeSH Terms
Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1.
Pirazzoli V, Nebhan C, Song X, Wurtz A, Walther Z, Cai G, Zhao Z, Jia P, de Stanchina E, Shapiro EM, Gale M, Yin R, Horn L, Carbone DP, Stephens PJ, Miller V, Gettinger S, Pao W, Politi K
(2014) Cell Rep 7: 999-1008
MeSH Terms: Adenocarcinoma, Adenocarcinoma of Lung, Afatinib, Animals, Antibodies, Monoclonal, Humanized, Antineoplastic Combined Chemotherapy Protocols, Cell Line, Tumor, Cetuximab, Drug Resistance, Neoplasm, ErbB Receptors, Humans, Lung Neoplasms, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Nude, Mice, Transgenic, Multiprotein Complexes, Mutation, Quinazolines, Random Allocation, TOR Serine-Threonine Kinases, Xenograft Model Antitumor Assays
Added May 27, 2014
0 Communities
2 Members
0 Resources
22 MeSH Terms