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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Bergmann glial Sonic hedgehog signaling activity is required for proper cerebellar cortical expansion and architecture.
Cheng FY, Fleming JT, Chiang C
(2018) Dev Biol 440: 152-166
MeSH Terms: Animals, Astrocytes, Cell Differentiation, Cell Division, Cell Proliferation, Cells, Cultured, Cerebellar Cortex, Cerebellar Neoplasms, Cerebellum, Developmental Disabilities, Hedgehog Proteins, Mice, Nervous System Malformations, Neural Stem Cells, Neuroglia, Neurons, Purkinje Cells, Signal Transduction, Wnt Signaling Pathway
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ
(2017) Oncogene 36: 6306-6314
MeSH Terms: Anilides, Animals, Cell Line, Tumor, Cerebellar Neoplasms, Disease Models, Animal, HEK293 Cells, Hedgehog Proteins, Humans, Male, Medulloblastoma, Mice, Mice, Transgenic, Pyridines, Random Allocation, SOXB1 Transcription Factors, Small Molecule Libraries, TRPC Cation Channels, Transfection, Tumor Suppressor Protein p53, Veratrum Alkaloids, Wnt Proteins, Wnt Signaling Pathway
Added July 18, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
Wen J, Lee J, Malhotra A, Nahta R, Arnold AR, Buss MC, Brown BD, Maier C, Kenney AM, Remke M, Ramaswamy V, Taylor MD, Castellino RC
(2016) Oncogene 35: 5552-5564
MeSH Terms: Animals, Biomarkers, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Cerebellar Neoplasms, Gene Knockdown Techniques, Hedgehog Proteins, Humans, Medulloblastoma, Mice, Mice, Transgenic, NIH 3T3 Cells, Neural Stem Cells, Protein Phosphatase 2C, Signal Transduction, Tumor Suppressor Protein p53
Added April 25, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Active medulloblastoma enhancers reveal subgroup-specific cellular origins.
Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA
(2016) Nature 530: 57-62
MeSH Terms: Animals, Cerebellar Neoplasms, Enhancer Elements, Genetic, Female, Gene Expression Regulation, Neoplastic, Gene Regulatory Networks, Genes, Neoplasm, Genes, Reporter, Humans, Male, Medulloblastoma, Mice, Reproducibility of Results, Transcription Factors, Zebrafish
Added February 15, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM
(2016) Oncogene 35: 4256-68
MeSH Terms: Animals, Cell Line, Tumor, Cell Proliferation, Cerebellar Neoplasms, Cerebellum, Gene Expression Regulation, Neoplastic, Hedgehog Proteins, Insulin-Like Growth Factor II, Medulloblastoma, Mice, Neural Stem Cells, Signal Transduction, Y-Box-Binding Protein 1
Added April 25, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, Dubuc A, Yao Y, Ramaswamy V, Luu B, Rolider A, Cavalli FM, Wang X, Remke M, Wu X, Chiu RY, Chu A, Chuah E, Corbett RD, Hoad GR, Jackman SD, Li Y, Lo A, Mungall KL, Nip KM, Qian JQ, Raymond AG, Thiessen NT, Varhol RJ, Birol I, Moore RA, Mungall AJ, Holt R, Kawauchi D, Roussel MF, Kool M, Jones DT, Witt H, Fernandez-L A, Kenney AM, Wechsler-Reya RJ, Dirks P, Aviv T, Grajkowska WA, Perek-Polnik M, Haberler CC, Delattre O, Reynaud SS, Doz FF, Pernet-Fattet SS, Cho BK, Kim SK, Wang KC, Scheurlen W, Eberhart CG, Fèvre-Montange M, Jouvet A, Pollack IF, Fan X, Muraszko KM, Gillespie GY, Di Rocco C, Massimi L, Michiels EM, Kloosterhof NK, French PJ, Kros JM, Olson JM, Ellenbogen RG, Zitterbart K, Kren L, Thompson RC, Cooper MK, Lach B, McLendon RE, Bigner DD, Fontebasso A, Albrecht S, Jabado N, Lindsey JC, Bailey S, Gupta N, Weiss WA, Bognár L, Klekner A, Van Meter TE, Kumabe T, Tominaga T, Elbabaa SK, Leonard JR, Rubin JB, Liau LM, Van Meir EG, Fouladi M, Nakamura H, Cinalli G, Garami M, Hauser P, Saad AG, Iolascon A, Jung S, Carlotti CG, Vibhakar R, Ra YS, Robinson S, Zollo M, Faria CC, Chan JA, Levy ML, Sorensen PH, Meyerson M, Pomeroy SL, Cho YJ, Bader GD, Tabori U, Hawkins CE, Bouffet E, Scherer SW, Rutka JT, Malkin D, Clifford SC, Jones SJ, Korbel JO, Pfister SM, Marra MA, Taylor MD
(2012) Nature 488: 49-56
MeSH Terms: Carrier Proteins, Cerebellar Neoplasms, Child, DNA Copy Number Variations, Gene Duplication, Genes, myc, Genome, Human, Genomic Structural Variation, Genomics, Hedgehog Proteins, Humans, Medulloblastoma, NF-kappa B, Nerve Tissue Proteins, Oncogene Proteins, Fusion, Proteins, RNA, Long Noncoding, Signal Transduction, Transforming Growth Factor beta, Translocation, Genetic
Added March 21, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
Garcia I, Crowther AJ, Gama V, Miller CR, Miller CR, Deshmukh M, Gershon TR
(2013) Oncogene 32: 2304-14
MeSH Terms: Animals, Apoptosis, Cell Differentiation, Cell Movement, Cerebellar Neoplasms, Cerebellum, Down-Regulation, Medulloblastoma, Mice, Mice, Transgenic, Neurogenesis, Proto-Oncogene Proteins c-bcl-2, Receptors, G-Protein-Coupled, Smoothened Receptor, Stem Cells, bcl-2-Associated X Protein
Added October 26, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Pediatric cerebellar pilomyxoid-spectrum astrocytomas.
Forbes JA, Mobley BC, O'Lynnger TM, Cooper CM, Ghiassi M, Hanif R, Pearson MM
(2011) J Neurosurg Pediatr 8: 90-6
MeSH Terms: Astrocytoma, Cerebellar Neoplasms, Cerebellum, Cerebral Ventricle Neoplasms, Chemotherapy, Adjuvant, Child, Preschool, Combined Modality Therapy, Cranial Fossa, Posterior, Craniotomy, Diffusion Magnetic Resonance Imaging, Disease Progression, Dissection, Female, Fourth Ventricle, Humans, Infant, Magnetic Resonance Imaging, Meninges, Neoplasm Invasiveness, Neoplasm Recurrence, Local, Neurologic Examination, Skull Base Neoplasms
Added August 14, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Intracranial orthotopic allografting of medulloblastoma cells in immunocompromised mice.
Huang X, Sarangi A, Ketova T, Litingtung Y, Cooper MK, Chiang C
(2010) J Vis Exp :
MeSH Terms: Animals, Cell Line, Tumor, Cerebellar Neoplasms, Immunocompromised Host, Medulloblastoma, Mice, Neoplasm Transplantation, Transplantation, Homologous
Added January 23, 2013
0 Communities
2 Members
0 Resources
8 MeSH Terms
c-myc overexpression causes anaplasia in medulloblastoma.
Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG
(2006) Cancer Res 66: 673-81
MeSH Terms: Anaplasia, Animals, Apoptosis, Cell Proliferation, Cerebellar Neoplasms, Humans, Medulloblastoma, Mice, Necrosis, Proto-Oncogene Proteins c-myc, Transplantation, Heterologous, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms