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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 203

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Regulation of tissue iron homeostasis: the macrophage "ferrostat".
Winn NC, Volk KM, Hasty AH
(2020) JCI Insight 5:
MeSH Terms: Adipose Tissue, Animals, Bone Marrow, Bone and Bones, Central Nervous System, Disease, Erythropoiesis, Health, Homeostasis, Humans, Iron, Liver, Macrophages, Muscle, Skeletal, Myocardium, Pancreas, Skin, Spleen, Wound Healing
Added March 3, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Unmet need in rheumatology: reports from the Targeted Therapies meeting 2019.
Winthrop KL, Weinblatt ME, Bathon J, Burmester GR, Mease PJ, Crofford L, Bykerk V, Dougados M, Rosenbaum JT, Mariette X, Sieper J, Melchers F, Cronstein BN, Breedveld FC, Kalden J, Smolen JS, Furst D
(2020) Ann Rheum Dis 79: 88-93
MeSH Terms: Arthritis, Psoriatic, Arthritis, Rheumatoid, Biomedical Research, Central Nervous System Sensitization, Clinical Trials as Topic, Congresses as Topic, Humans, Lupus Erythematosus, Systemic, Molecular Targeted Therapy, Needs Assessment, Research, Research Design, Rheumatic Diseases, Rheumatology, Spondylitis, Ankylosing
Added March 25, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Watanabe M, Zhang J, Mansuri MS, Duan J, Karimy JK, Delpire E, Alper SL, Lifton RP, Fukuda A, Kahle KT
(2019) Sci Signal 12:
MeSH Terms: Animals, Animals, Newborn, Binding Sites, Cells, Cultured, Central Nervous System, Chlorides, Gene Expression Regulation, Developmental, Male, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Neurons, Phosphorylation, Signal Transduction, Symporters, gamma-Aminobutyric Acid
Added March 18, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Functional Coupling of K-Cl Cotransporter (KCC) to GABA-Gated Cl Channels in the Central Nervous System of Drosophila melanogaster Leads to Altered Drug Sensitivities.
Chen R, Prael FJ, Li Z, Delpire E, Weaver CD, Swale DR
(2019) ACS Chem Neurosci 10: 2765-2776
MeSH Terms: Animals, Central Nervous System, Chloride Channels, Drosophila Proteins, Drosophila melanogaster, Insecticide Resistance, Neurons, Signal Transduction, Symporters, Synaptic Transmission, gamma-Aminobutyric Acid
Added April 10, 2019
0 Communities
2 Members
0 Resources
11 MeSH Terms
Surveying heterocycles as amide bioisosteres within a series of mGlu NAMs: Discovery of VU6019278.
Reed CW, Washecheck JP, Quitlag MC, Jenkins MT, Rodriguez AL, Engers DW, Blobaum AL, Conn PJ, Niswender CM, Lindsley CW
(2019) Bioorg Med Chem Lett 29: 1211-1214
MeSH Terms: Allosteric Regulation, Amides, Animals, Central Nervous System, Hepatocytes, Heterocyclic Compounds, Inhibitory Concentration 50, Pyrazoles, Rats, Receptors, Metabotropic Glutamate, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The in vivo specificity of synaptic Gβ and Gγ subunits to the α adrenergic receptor at CNS synapses.
Yim YY, Betke KM, McDonald WH, Gilsbach R, Chen Y, Hyde K, Wang Q, Hein L, Hamm HE
(2019) Sci Rep 9: 1718
MeSH Terms: Animals, Central Nervous System, Epinephrine, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Gene Knock-In Techniques, Mice, Proteomics, Receptors, Adrenergic, alpha-2, Signal Transduction, Synapses
Added March 24, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Posttraumatic Stress Symptoms Mediate the Effects of Trauma Exposure on Clinical Indicators of Central Sensitization in Patients With Chronic Pain.
McKernan LC, Johnson BN, Crofford LJ, Lumley MA, Bruehl S, Cheavens JS
(2019) Clin J Pain 35: 385-393
MeSH Terms: Adult, Central Nervous System Sensitization, Chronic Pain, Female, Humans, Male, Middle Aged, Self Report, Stress Disorders, Post-Traumatic, Surveys and Questionnaires
Added March 25, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores.
Childress ES, Wieting JM, Felts AS, Breiner MM, Long MF, Luscombe VB, Rodriguez AL, Cho HP, Blobaum AL, Niswender CM, Emmitte KA, Conn PJ, Lindsley CW
(2019) J Med Chem 62: 378-384
MeSH Terms: Allosteric Regulation, Amides, Animals, Central Nervous System, Drug Evaluation, Preclinical, Half-Life, Humans, Inhibitory Concentration 50, Protein Isoforms, Pyrazoles, Pyridines, Pyrimidines, Rats, Receptors, Metabotropic Glutamate, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Lack of consistent sex differences in D-amphetamine-induced dopamine release measured with [F]fallypride PET.
Smith CT, Dang LC, Burgess LL, Perkins SF, San Juan MD, Smith DK, Cowan RL, Le NT, Kessler RM, Samanez-Larkin GR, Zald DH
(2019) Psychopharmacology (Berl) 236: 581-590
MeSH Terms: Adult, Aged, Benzamides, Central Nervous System Stimulants, Dextroamphetamine, Dopamine, Female, Fluorine Radioisotopes, Humans, Male, Middle Aged, Positron-Emission Tomography, Receptors, Dopamine D2, Receptors, Dopamine D3, Sex Characteristics, Sex Factors, Ventral Striatum, Young Adult
Added April 15, 2019
0 Communities
1 Members
0 Resources
18 MeSH Terms
Women Undergoing Third Line Overactive Bladder Treatment Demonstrate Elevated Thermal Temporal Summation.
Reynolds WS, Kowalik C, Cohn J, Kaufman M, Wein A, Dmochowski R, Bruehl S
(2018) J Urol 200: 856-861
MeSH Terms: Adult, Aged, Botulinum Toxins, Type A, Central Nervous System Sensitization, Cohort Studies, Female, Follow-Up Studies, Hot Temperature, Humans, Linear Models, Lumbosacral Plexus, Middle Aged, Pain Perception, Retrospective Studies, Risk Assessment, Severity of Illness Index, Temporal Lobe, Transcutaneous Electric Nerve Stimulation, Treatment Outcome, Urinary Bladder, Overactive
Added September 16, 2019
0 Communities
1 Members
0 Resources
MeSH Terms