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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 3154

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Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer.
Hoover AA, Hufnagel DH, Harris W, Bullock K, Glass EB, Liu E, Barham W, Crispens MA, Khabele D, Giorgio TD, Wilson AJ, Yull FE
(2020) BMC Cancer 20: 970
MeSH Terms: Animals, Cell Line, Tumor, Disease Models, Animal, Disease Progression, Female, Humans, Macrophages, Mice, Mice, Transgenic, NF-kappa B, Signal Transduction
Added January 29, 2021
1 Communities
0 Members
0 Resources
11 MeSH Terms
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism.
Bayraktar EC, La K, Karpman K, Unlu G, Ozerdem C, Ritter DJ, Alwaseem H, Molina H, Hoffmann HH, Millner A, Atilla-Gokcumen GE, Gamazon ER, Rushing AR, Knapik EW, Basu S, Birsoy K
(2020) Nat Metab 2: 487-498
MeSH Terms: Animals, Cell Line, Cell Proliferation, Cholesterol, Gene Expression Regulation, Golgi Apparatus, Humans, Hyperlipidemias, Lipid Metabolism, Membrane Proteins, Proprotein Convertases, Serine Endopeptidases, Sterol Regulatory Element Binding Proteins, Zebrafish
Added September 9, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
N-[F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.
Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H
(2020) Bioorg Med Chem Lett 30: 127257
MeSH Terms: Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Cell Proliferation, Crizotinib, Dose-Response Relationship, Drug, Fluorine Radioisotopes, Humans, Lung Neoplasms, Molecular Imaging, Molecular Structure, Positron-Emission Tomography, Protein Kinase Inhibitors, Structure-Activity Relationship
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP
(2020) Science 368: 85-89
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cationic Amino Acid Transporter 1, Cell Line, Tumor, Cystathionine gamma-Lyase, Cysteine, Cystine, Ferroptosis, Gene Deletion, Humans, Mice, Mice, Mutant Strains, Pancreatic Neoplasms
Added March 13, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones.
Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS
(2020) Nat Genet 52: 418-427
MeSH Terms: Amino Acid Sequence, Animals, Cell Line, Chromatin, DNA, Female, Gene Expression Regulation, Developmental, Gene Regulatory Networks, Histones, Humans, Mice, Mice, Inbred C57BL, Nucleosomes, Transcription Factors, Transcription, Genetic
Added April 7, 2020
1 Communities
3 Members
0 Resources
15 MeSH Terms
Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
Schafer JM, Lehmann BD, Gonzalez-Ericsson PI, Marshall CB, Beeler JS, Redman LN, Jin H, Sanchez V, Stubbs MC, Scherle P, Johnson KN, Sheng Q, Roland JT, Bauer JA, Shyr Y, Chakravarthy B, Mobley BC, Hiebert SW, Balko JM, Sanders ME, Liu PCC, Pietenpol JA
(2020) Sci Transl Med 12:
MeSH Terms: Cell Line, Tumor, Humans, Mitogen-Activated Protein Kinase Kinases, N-Myc Proto-Oncogene Protein, Neoplasm Recurrence, Local, Triple Negative Breast Neoplasms
Added March 30, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Development of a novel murine model of lymphatic metastasis.
Banan B, Beckstead JA, Dunavant LE, Sohn Y, Adcock JM, Nomura S, Abumrad N, Goldenring JR, Fingleton B
(2020) Clin Exp Metastasis 37: 247-255
MeSH Terms: Animals, Cell Line, Tumor, Colonic Neoplasms, Disease Models, Animal, Female, Green Fluorescent Proteins, Humans, Luciferases, Luminescent Measurements, Lymph Nodes, Lymphatic Metastasis, Lymphatic Vessels, Male, Mesentery, Mice, Mice, Inbred C57BL, Stomach Neoplasms, Tomography, Optical, Tumor Burden
Added March 24, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular manganese.
Horning KJ, Joshi P, Nitin R, Balachandran RC, Yanko FM, Kim K, Christov P, Aschner M, Sulikowski GA, Weaver CD, Bowman AB
(2020) J Biol Chem 295: 3875-3890
MeSH Terms: Animals, Calcimycin, Calcium, Cell Line, Cell Survival, Fura-2, HEK293 Cells, Humans, Induced Pluripotent Stem Cells, Ionomycin, Ionophores, Male, Manganese, Mass Spectrometry, Mice
Added March 27, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
A mutation in the Na-K-2Cl cotransporter-1 leads to changes in cellular metabolism.
Omer S, Koumangoye R, Delpire E
(2020) J Cell Physiol 235: 7239-7250
MeSH Terms: Adolescent, Animals, Cell Line, DNA, Mitochondrial, Dogs, Energy Metabolism, Female, Fibroblasts, Glycolysis, Humans, Madin Darby Canine Kidney Cells, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Microscopy, Electron, Transmission, Mitochondria, Multiple Organ Failure, Mutant Proteins, Mutation, Recombinant Fusion Proteins, Sequence Deletion, Solute Carrier Family 12, Member 2
Added February 28, 2020
1 Communities
1 Members
0 Resources
22 MeSH Terms
Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE
(2020) Immunity 52: 388-403.e12
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Cell Line, Disease Models, Animal, Drug Therapy, Combination, Ebolavirus, Epitopes, Female, Glycoproteins, Hemorrhagic Fever, Ebola, Humans, Immunoglobulin Fab Fragments, Macaca mulatta, Male, Mice, Mice, Inbred BALB C, Molecular Mimicry, Protein Conformation
Added March 31, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms