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Survivorship in immune therapy: Assessing toxicities, body composition and health-related quality of life among long-term survivors treated with antibodies to programmed death-1 receptor and its ligand.
Patrinely JR, Young AC, Quach H, Williams GR, Ye F, Fan R, Horn L, Beckermann KE, Gillaspie EA, Sosman JA, Friedman DL, Moslehi JJ, Johnson DB
(2020) Eur J Cancer 135: 211-220
MeSH Terms: Aged, Antineoplastic Agents, Immunological, B7-H1 Antigen, Body Composition, Female, Functional Status, Humans, Immune Checkpoint Inhibitors, Male, Middle Aged, Neoplasms, Nutritional Status, Programmed Cell Death 1 Receptor, Progression-Free Survival, Quality of Life, Retrospective Studies, Survivors, Time Factors
Added September 29, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Increased Expression of PD-1 and PD-L1 in Patients With Laryngotracheal Stenosis.
Davis RJ, Lina I, Ding D, Engle EL, Taube J, Gelbard A, Hillel AT
(2021) Laryngoscope 131: 967-974
MeSH Terms: B7-H1 Antigen, Biopsy, Case-Control Studies, Cells, Cultured, Cricoid Cartilage, Female, Fibroblasts, Fibrosis, Humans, Immunohistochemistry, Laryngostenosis, Male, Middle Aged, Primary Cell Culture, Programmed Cell Death 1 Receptor, Trachea, Tracheal Stenosis, Tracheostomy
Added July 30, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Evolving insights into the mechanisms of toxicity associated with immune checkpoint inhibitor therapy.
Mangan BL, McAlister RK, Balko JM, Johnson DB, Moslehi JJ, Gibson A, Phillips EJ
(2020) Br J Clin Pharmacol 86: 1778-1789
MeSH Terms: Drug-Related Side Effects and Adverse Reactions, Humans, Immune Checkpoint Inhibitors, Incidence, Melanoma, Neoplasms, Programmed Cell Death 1 Receptor
Added September 29, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
COVID-19 and immune checkpoint inhibitors: initial considerations.
Sullivan RJ, Johnson DB, Rini BI, Neilan TG, Lovly CM, Moslehi JJ, Reynolds KL
(2020) J Immunother Cancer 8:
MeSH Terms: Antineoplastic Agents, Immunological, COVID-19, Coronavirus Infections, Humans, Molecular Targeted Therapy, Neoplasms, Pandemics, Pneumonia, Viral, Programmed Cell Death 1 Receptor
Added May 29, 2020
0 Communities
2 Members
0 Resources
9 MeSH Terms
A connection in life and death: The BCL-2 family coordinates mitochondrial network dynamics and stem cell fate.
Rasmussen ML, Gama V
(2020) Int Rev Cell Mol Biol 353: 255-284
MeSH Terms: Animals, Cell Death, Cell Differentiation, Humans, Mitochondria, Mitochondrial Dynamics, Proto-Oncogene Proteins c-bcl-2, Stem Cells
Added August 24, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Demographic Factors Associated with Toxicity in Patients Treated with Anti-Programmed Cell Death-1 Therapy.
Shah KP, Song H, Ye F, Moslehi JJ, Balko JM, Salem JE, Johnson DB
(2020) Cancer Immunol Res 8: 851-855
MeSH Terms: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Antineoplastic Agents, Immunological, CTLA-4 Antigen, Female, Hospitalization, Humans, Immunologic Factors, Immunotherapy, Length of Stay, Male, Melanoma, Middle Aged, Programmed Cell Death 1 Receptor, Risk Factors, Young Adult
Added May 29, 2020
0 Communities
1 Members
0 Resources
19 MeSH Terms
Solid organ transplant rejection associated with immune-checkpoint inhibitors.
Saberianfar S, Nguyen LS, Manouchehri A, Lebrun-Vignes B, Moslehi JJ, Johnson DB, Hertig A, Salem JE
(2020) Ann Oncol 31: 543-544
MeSH Terms: Humans, Immune Checkpoint Inhibitors, Organ Transplantation, Programmed Cell Death 1 Receptor
Added May 29, 2020
0 Communities
1 Members
0 Resources
4 MeSH Terms
Increased reporting of fatal hepatitis associated with immune checkpoint inhibitors.
Vozy A, De Martin E, Johnson DB, Lebrun-Vignes B, Moslehi JJ, Salem JE
(2019) Eur J Cancer 123: 112-115
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Immunological, B7-H1 Antigen, CTLA-4 Antigen, Chemical and Drug Induced Liver Injury, Child, Databases, Factual, Female, Hepatitis, Autoimmune, Humans, Ipilimumab, Male, Massive Hepatic Necrosis, Middle Aged, Neoplasms, Nivolumab, Programmed Cell Death 1 Receptor, World Health Organization, Young Adult
Added November 12, 2019
0 Communities
1 Members
0 Resources
23 MeSH Terms
Mycobacterium tuberculosis programs mesenchymal stem cells to establish dormancy and persistence.
Fatima S, Kamble SS, Dwivedi VP, Bhattacharya D, Kumar S, Ranganathan A, Van Kaer L, Mohanty S, Das G
(2020) J Clin Invest 130: 655-661
MeSH Terms: Animals, Autophagic Cell Death, Cellular Reprogramming, Disease Models, Animal, Humans, Lipids, Mesenchymal Stem Cells, Mice, Mycobacterium tuberculosis, Phagosomes, Tuberculosis
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms