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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney.
Grove KJ, Lareau NM, Voziyan PA, Zeng F, Harris RC, Hudson BG, Caprioli RM
(2018) Kidney Int 94: 292-302
MeSH Terms: Albumins, Albuminuria, Animals, Cathepsin D, Diabetic Nephropathies, Disease Models, Animal, Frozen Sections, Humans, Kidney Glomerulus, Kidney Tubules, Mice, Mice, Inbred C57BL, Molecular Imaging, Nitric Oxide Synthase Type III, Proteolysis, Renal Elimination, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added May 29, 2018
1 Communities
1 Members
0 Resources
17 MeSH Terms
Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium.
Pruitt FL, He Y, Franco OE, Jiang M, Cates JM, Hayward SW
(2013) Prostate 73: 476-88
MeSH Terms: Antigens, CD1, Cathepsin D, Cell Line, Cell Movement, Cell Transformation, Neoplastic, Epithelial Cells, Fibroblasts, Gene Expression Regulation, Neoplastic, Humans, Male, Paracrine Communication, Prostate, Prostatic Hyperplasia, Prostatic Neoplasms, RNA, Small Interfering, Stromal Cells, Up-Regulation
Added December 10, 2013
0 Communities
3 Members
0 Resources
17 MeSH Terms
A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.
Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SS
(2012) J Neurosci 32: 8633-48
MeSH Terms: Animals, Autophagy, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Blastocyst, Blotting, Western, Cathepsin D, Cell Line, Tumor, Cells, Cultured, DNA Primers, Gene Expression, Humans, Hydrogen-Ion Concentration, Lysosomes, Mice, Mice, Knockout, Neurons, Polymerase Chain Reaction, Presenilin-1, Presenilin-2, Presenilins, RNA, RNA, Small Interfering, Vacuolar Proton-Translocating ATPases
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.
Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, Hold G, Kunstmann E, Yoshimori T, Silverberg MS, Girardin SE, Philpott DJ, El Omar E, Jones NL
(2012) Gastroenterology 142: 1160-71
MeSH Terms: Alleles, Animals, Autophagy, Bacterial Proteins, Cathepsin D, Crohn Disease, Genotype, Helicobacter Infections, Helicobacter pylori, Humans, Immunity, Innate, Mice, Phagosomes
Added September 3, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms
Preclinical validation of salivary biomarkers for primary Sjögren's syndrome.
Hu S, Gao K, Pollard R, Arellano-Garcia M, Zhou H, Zhang L, Elashoff D, Kallenberg CG, Vissink A, Wong DT
(2010) Arthritis Care Res (Hoboken) 62: 1633-8
MeSH Terms: Adult, Biomarkers, Cathepsin D, Cohort Studies, Female, Humans, Middle Aged, Phosphopyruvate Hydratase, RNA, Messenger, Saliva, Sjogren's Syndrome, beta 2-Microglobulin
Added October 15, 2011
0 Communities
1 Members
0 Resources
12 MeSH Terms
Multivariable difference gel electrophoresis and mass spectrometry: a case study on transforming growth factor-beta and ERBB2 signaling.
Friedman DB, Wang SE, Whitwell CW, Caprioli RM, Arteaga CL
(2007) Mol Cell Proteomics 6: 150-69
MeSH Terms: Amino Acid Sequence, Cathepsin D, Cluster Analysis, Electrophoresis, Gel, Two-Dimensional, Genes, Tumor Suppressor, Humans, Hydrogen-Ion Concentration, Mass Spectrometry, Metabolic Networks and Pathways, Molecular Sequence Data, Multivariate Analysis, Principal Component Analysis, Proteome, Receptor, ErbB-2, Reproducibility of Results, Serpins, Signal Transduction, Time Factors, Transforming Growth Factor beta1
Added March 5, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses.
Myllykangas L, Tyynelä J, Page-McCaw A, Rubin GM, Haltia MJ, Feany MB
(2005) Neurobiol Dis 19: 194-9
MeSH Terms: Amino Acid Sequence, Animals, Cathepsin D, Drosophila Proteins, Drosophila melanogaster, Molecular Sequence Data, Neuronal Ceroid-Lipofuscinoses
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells.
Fonteneau JF, Kavanagh DG, Lirvall M, Sanders C, Cover TL, Bhardwaj N, Larsson M
(2003) Blood 102: 4448-55
MeSH Terms: ATP-Binding Cassette Transporters, Antigen Presentation, Apoptosis, CD8-Positive T-Lymphocytes, Cathepsin D, Cells, Cultured, Cysteine Endopeptidases, Cytosol, Dendritic Cells, Endosomes, HLA-A2 Antigen, Histocompatibility Antigens Class I, Humans, Hydrogen-Ion Concentration, Leukocytes, Mononuclear, Multienzyme Complexes, Necrosis, Phagocytosis, Pinocytosis, Proteasome Endopeptidase Complex, Vaccinia virus
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.
Ebert DH, Wetzel JD, Brumbaugh DE, Chance SR, Stobie LE, Baer GS, Dermody TS
(2001) J Virol 75: 3197-206
MeSH Terms: Adaptation, Physiological, Animals, Capsid, Capsid Proteins, Cathepsin D, Cathepsin L, Cathepsins, Cysteine Endopeptidases, Cysteine Proteinase Inhibitors, Endopeptidases, L Cells, Leucine, Mice, Mutation, RNA-Binding Proteins, Reoviridae, Structure-Activity Relationship, Virus Assembly
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Cytosolic and membrane-bound methemoglobin reductases in erythrocytes of the opossum, Didelphis virginiana.
Bethlenfalvay NC, Waterman MR, Lima JE, Waldrup T
(1982) Comp Biochem Physiol B 73: 591-4
MeSH Terms: Animals, Cathepsin D, Cathepsins, Cytochrome-B(5) Reductase, Cytosol, Erythrocyte Membrane, Erythrocytes, Humans, Isoelectric Focusing, NADH, NADPH Oxidoreductases, Octoxynol, Opossums, Polyethylene Glycols
Added February 12, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms