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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC
(2014) Clin Cancer Res 20: 2126-35
MeSH Terms: Amino Acid Chloromethyl Ketones, Animals, Apoptosis, Caspase 3, Caspase Inhibitors, Cell Line, Tumor, Colonic Neoplasms, Colorectal Neoplasms, Female, Fluorine Radioisotopes, Fluorobenzenes, Humans, Imidazoles, Immunoblotting, Immunohistochemistry, Indoles, Mice, Inbred C57BL, Mice, Nude, Organophosphates, Peptides, Positron-Emission Tomography, Protein Kinase Inhibitors, Quinazolines, Quinolines, Radiopharmaceuticals, Sulfonamides, Tissue Distribution, Xenograft Model Antitumor Assays
Added March 20, 2014
1 Communities
3 Members
0 Resources
28 MeSH Terms
Dexamethasone protects auditory hair cells against TNFalpha-initiated apoptosis via activation of PI3K/Akt and NFkappaB signaling.
Haake SM, Dinh CT, Chen S, Eshraghi AA, Van De Water TR
(2009) Hear Res 255: 22-32
MeSH Terms: Animals, Apoptosis, Benzyl Compounds, Caspase Inhibitors, Dexamethasone, Dose-Response Relationship, Drug, Hair Cells, Auditory, Hydrocarbons, Fluorinated, In Vitro Techniques, NF-kappa B, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Rats, Rats, Sprague-Dawley, Receptors, Glucocorticoid, Signal Transduction, Tumor Necrosis Factor-alpha
Added April 18, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway.
Nagaraj NS, Anilakumar KR, Singh OV
(2010) J Nutr Biochem 21: 405-12
MeSH Terms: Allyl Compounds, Anticarcinogenic Agents, Antineoplastic Agents, Phytogenic, Apoptosis, Apoptotic Protease-Activating Factor 1, Caspase 3, Caspase 9, Caspase Inhibitors, Cell Line, Tumor, Chemoprevention, Cystatin B, Cytochromes c, Disulfides, Fas-Associated Death Domain Protein, Garlic, Gene Expression Regulation, Neoplastic, Humans, Mitochondria, Neoplasms, Plant Roots, Protein Transport, Signal Transduction, bcl-2-Associated X Protein
Added June 14, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models.
Brooks C, Wei Q, Cho SG, Dong Z
(2009) J Clin Invest 119: 1275-85
MeSH Terms: Adenosine Triphosphate, Animals, Apoptosis, Caspase Inhibitors, Cell Line, Cells, Cultured, Cisplatin, Cytochromes c, Dynamins, Enzyme Inhibitors, GTP Phosphohydrolases, Imaging, Three-Dimensional, Kidney Tubular Necrosis, Acute, Kidney Tubules, Proximal, Male, Mice, Mice, Inbred C57BL, Microtubule-Associated Proteins, Mitochondria, Proto-Oncogene Proteins c-bcl-2, RNA, Small Interfering, Rats, Reperfusion Injury, Sodium Azide
Added September 12, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression.
Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K
(2009) Cancer Res 69: 1080-8
MeSH Terms: Animals, Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein, Caspase 8, Caspase Inhibitors, Cell Line, Tumor, Enzyme Activation, Fas Ligand Protein, Humans, Immunohistochemistry, Interferon Regulatory Factors, Mice, Mitochondria, RNA, Messenger, RNA, Small Interfering, Receptors, TNF-Related Apoptosis-Inducing Ligand, Sarcoma, Sarcoma, Experimental, TNF-Related Apoptosis-Inducing Ligand
Added September 12, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
PPAR-gamma agonist protects podocytes from injury.
Kanjanabuch T, Ma LJ, Chen J, Pozzi A, Guan Y, Mundel P, Fogo AB
(2007) Kidney Int 71: 1232-9
MeSH Terms: Animals, Apoptosis, Caspase Inhibitors, Cell Proliferation, Cells, Cultured, Cyclin-Dependent Kinase Inhibitor p27, Kidney Glomerulus, Mice, Necrosis, PPAR gamma, Pioglitazone, Plasmids, Podocytes, Puromycin Aminonucleoside, RNA, Messenger, Thiazolidinediones, Transforming Growth Factor beta, bcl-X Protein
Added January 20, 2012
1 Communities
1 Members
0 Resources
18 MeSH Terms
Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.
Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL, Matsuyama S
(2006) Exp Cell Res 312: 488-99
MeSH Terms: Acetylcysteine, Amino Acid Chloromethyl Ketones, Antigens, Nuclear, Apoptosis, Caspase Inhibitors, Cell Line, Cysteine Proteinase Inhibitors, DNA-Binding Proteins, Doxorubicin, Gene Expression, HeLa Cells, Humans, Ku Autoantigen, Leupeptins, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Signal Transduction, Staurosporine, Ubiquitin, Ubiquitin-Protein Ligase Complexes
Added October 26, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Induction of manganese superoxide dismutase (MnSOD) mediates cardioprotective effect of tamoxifen (TAM).
Daosukho C, Ittarat W, Lin SM, Sawyer DB, Kiningham K, Lien YC, St Clair DK
(2005) J Mol Cell Cardiol 39: 792-803
MeSH Terms: Animals, Apoptosis, Cardiotonic Agents, Caspase Inhibitors, Caspases, Doxorubicin, Enzyme Induction, Formazans, Gene Expression, Genotype, In Situ Nick-End Labeling, Male, Mice, Myocytes, Cardiac, RNA, Messenger, Superoxide Dismutase, Tamoxifen, Tetrazolium Salts
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Expression of c-FLIP in classic and nodular lymphocyte-predominant Hodgkin lymphoma.
Uherova P, Olson S, Thompson MA, Juskevicius R, Hamilton KS
(2004) Appl Immunohistochem Mol Morphol 12: 105-10
MeSH Terms: Adolescent, Adult, Aged, Antigens, CD, Antigens, Neoplasm, CASP8 and FADD-Like Apoptosis Regulating Protein, Carrier Proteins, Caspase Inhibitors, Cell Transformation, Neoplastic, Child, Child, Preschool, Female, Hodgkin Disease, Humans, Immunohistochemistry, Intracellular Signaling Peptides and Proteins, Lymph Nodes, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Male, Middle Aged
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling.
McLaughlin B
(2004) Apoptosis 9: 111-21
MeSH Terms: Animals, Brain, Brain Ischemia, Calpain, Caspase Inhibitors, Caspases, Central Nervous System, Enzyme Inhibitors, Humans, Nervous System Diseases, Proteasome Endopeptidase Complex
Added January 26, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms