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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 52

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Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells.
Dos Santos AA, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M
(2018) Food Chem Toxicol 113: 328-336
MeSH Terms: Animals, Astrocytes, Caspase 3, Caspase 9, Cell Death, Cells, Cultured, Enzyme Activation, Lim Kinases, Methylmercury Compounds, Mice, Inbred C57BL, Myosin-Light-Chain Phosphatase, Oxidative Stress, Phosphorylation, Proteolysis, rho-Associated Kinases
Added April 11, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand.
Rellinger EJ, Padmanabhan C, Qiao J, Appert A, Waterson AG, Lindsley CW, Beauchamp RD, Chung DH
(2017) Biochem Biophys Res Commun 491: 463-468
MeSH Terms: Antigens, CD, Antineoplastic Agents, Apoptosis, Cadherins, Caspase 3, Cell Cycle, Cell Line, Tumor, Drug Synergism, Epithelial-Mesenchymal Transition, Gene Expression Regulation, Humans, Isoxazoles, Mesenchymal Stem Cells, Niacinamide, Poly(ADP-ribose) Polymerases, Sarcoma, Ewing, Signal Transduction, Small Molecule Libraries, TNF-Related Apoptosis-Inducing Ligand, Vimentin
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer.
Wilson AJ, Saskowski J, Barham W, Yull F, Khabele D
(2015) J Ovarian Res 8: 46
MeSH Terms: Animals, Apoptosis, Benzoquinones, Caspase 3, Cell Line, Tumor, Cell Proliferation, Cell Survival, Cisplatin, Disease Models, Animal, Female, Gene Expression Regulation, Neoplastic, Humans, Mice, NF-kappa B, Ovarian Neoplasms, Tumor Necrosis Factor-alpha
Added October 6, 2015
0 Communities
4 Members
0 Resources
16 MeSH Terms
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J
(2015) Cell Death Dis 6: e1729
MeSH Terms: Caspase 3, Cell Death, Colonic Neoplasms, DNA Damage, HCT116 Cells, HEK293 Cells, HT29 Cells, Humans, Nuclear Pore Complex Proteins, RNA-Binding Proteins, Transfection
Added July 28, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
EGF receptor deletion in podocytes attenuates diabetic nephropathy.
Chen J, Chen JK, Harris RC
(2015) J Am Soc Nephrol 26: 1115-25
MeSH Terms: Albuminuria, Animals, Caspase 3, Diabetic Nephropathies, ErbB Receptors, Hyperglycemia, Male, Mice, Knockout, Podocytes, Proto-Oncogene Proteins c-bcl-2, Reactive Oxygen Species, Signal Transduction, Smad Proteins, Receptor-Regulated, Transforming Growth Factor beta, src-Family Kinases
Added October 27, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms
The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury.
Tchantchou F, Tucker LB, Fu AH, Bluett RJ, McCabe JT, Patel S, Zhang Y
(2014) Neuropharmacology 85: 427-39
MeSH Terms: Amidohydrolases, Animals, Anxiety, Brain, Brain Injuries, Caspase 3, Disease Models, Animal, Extracellular Signal-Regulated MAP Kinases, Male, Memory Disorders, Mice, Inbred C57BL, Motor Activity, Neuroimmunomodulation, Neuroprotective Agents, Piperidines, Proto-Oncogene Proteins c-akt, Pyridines, Receptor, Cannabinoid, CB1, Receptor, Cannabinoid, CB2, Recovery of Function
Added January 20, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice.
Zeng F, Miyazawa T, Kloepfer LA, Harris RC
(2014) Kidney Int 86: 538-47
MeSH Terms: Animals, Apoptosis, Blood Urea Nitrogen, Caspase 3, Cell Proliferation, Cyclin D, Cyclin-Dependent Kinase Inhibitor p21, Cyclin-Dependent Kinase Inhibitor p27, Disease Models, Animal, Disease Progression, Epithelial Cells, Fibrosis, Gene Deletion, Kidney Cortex, Kidney Medulla, Mice, Organ Size, Polycystic Kidney Diseases, Receptor, ErbB-4
Added October 27, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms
A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.
Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC
(2014) Clin Cancer Res 20: 2126-35
MeSH Terms: Amino Acid Chloromethyl Ketones, Animals, Apoptosis, Caspase 3, Caspase Inhibitors, Cell Line, Tumor, Colonic Neoplasms, Colorectal Neoplasms, Female, Fluorine Radioisotopes, Fluorobenzenes, Humans, Imidazoles, Immunoblotting, Immunohistochemistry, Indoles, Mice, Inbred C57BL, Mice, Nude, Organophosphates, Peptides, Positron-Emission Tomography, Protein Kinase Inhibitors, Quinazolines, Quinolines, Radiopharmaceuticals, Sulfonamides, Tissue Distribution, Xenograft Model Antitumor Assays
Added March 20, 2014
1 Communities
3 Members
0 Resources
28 MeSH Terms
ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone.
Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A
(2014) Cancer Res 74: 1404-15
MeSH Terms: ADAM Proteins, ADAM17 Protein, Antigens, CD, Biomarkers, Tumor, Bone and Bones, Caspase 3, Cell Adhesion Molecules, Neuronal, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Cellular Microenvironment, Disease Progression, Fetal Proteins, Humans, Male, Neoplasm Metastasis, Prostatic Neoplasms, Transforming Growth Factor beta
Added February 17, 2014
1 Communities
6 Members
0 Resources
19 MeSH Terms
Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Kook S, Zhan X, Cleghorn WM, Benovic JL, Gurevich VV, Gurevich EV
(2014) Cell Death Differ 21: 172-84
MeSH Terms: Animals, Apoptosis, Arrestins, BH3 Interacting Domain Death Agonist Protein, Caspase 3, Caspases, Cell Line, Cytochromes c, Etoposide, Mice, Mitochondria, Protein Binding, Protein Isoforms, Recombinant Proteins, Tumor Necrosis Factor-alpha
Added February 12, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms