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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 18

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Identification of drug-specific public TCR driving severe cutaneous adverse reactions.
Pan RY, Chu MT, Wang CW, Lee YS, Lemonnier F, Michels AW, Schutte R, Ostrov DA, Chen CB, Phillips EJ, Mallal SA, Mockenhaupt M, Bellón T, Tassaneeyakul W, White KD, Roujeau JC, Chung WH, Hung SI
(2019) Nat Commun 10: 3569
MeSH Terms: Adoptive Transfer, Adult, Aged, Animals, Carbamazepine, Disease Models, Animal, Female, HLA-B15 Antigen, Humans, Male, Mice, Transgenic, Middle Aged, Receptor-CD3 Complex, Antigen, T-Cell, Receptors, Antigen, T-Cell, alpha-beta, Severity of Illness Index, Skin, Stevens-Johnson Syndrome, T-Lymphocytes, Cytotoxic
Added March 30, 2020
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MeSH Terms
Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions.
Nicoletti P, Barrett S, McEvoy L, Daly AK, Aithal G, Lucena MI, Andrade RJ, Wadelius M, Hallberg P, Stephens C, Bjornsson ES, Friedmann P, Kainu K, Laitinen T, Marson A, Molokhia M, Phillips E, Pichler W, Romano A, Shear N, Sills G, Tanno LK, Swale A, Floratos A, Shen Y, Nelson MR, Watkins PB, Daly MJ, Morris AP, Alfirevic A, Pirmohamed M
(2019) Clin Pharmacol Ther 106: 1028-1036
MeSH Terms: Adult, Anaplastic Lymphoma Kinase, Carbamazepine, Chemical and Drug Induced Liver Injury, Drug Hypersensitivity, Drug Hypersensitivity Syndrome, Europe, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, HLA-A Antigens, HLA-B Antigens, Humans, Male, Phenotype, Risk Factors, Stevens-Johnson Syndrome
Added March 30, 2020
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17 MeSH Terms
Controversies in drug allergy: Testing for delayed reactions.
Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, Lehloenya R, Mockenhaupt M, Peter J, Pirmohamed M, Roujeau JC, Shear NH, Tanno LK, Trubiano J, Valluzzi R, Barbaud A
(2019) J Allergy Clin Immunol 143: 66-73
MeSH Terms: Animals, Asian Continental Ancestry Group, Carbamazepine, Dideoxynucleosides, HLA-B Antigens, HLA-B15 Antigen, Humans, Skin Tests, Stevens-Johnson Syndrome
Added March 30, 2020
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MeSH Terms
Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.
Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL, Mushiroda T, Klein T, Gammal RS, Pirmohamed M
(2018) Clin Pharmacol Ther 103: 574-581
MeSH Terms: Anticonvulsants, Carbamazepine, Drug-Related Side Effects and Adverse Reactions, HLA-B Antigens, Humans, Oxcarbazepine, Pharmacogenetics
Added March 30, 2020
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MeSH Terms
KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects.
Bowerman M, Salsac C, Bernard V, Soulard C, Dionne A, Coque E, Benlefki S, Hince P, Dion PA, Butler-Browne G, Camu W, Bouchard JP, Delpire E, Rouleau GA, Raoul C, Scamps F
(2017) Neurobiol Dis 106: 35-48
MeSH Terms: Agenesis of Corpus Callosum, Animals, Carbamazepine, Cells, Cultured, Chlorides, Disease Models, Animal, Mice, Inbred C57BL, Mice, Transgenic, Motor Neurons, Neuromuscular Junction, Neurotransmitter Agents, Peripheral Nervous System Diseases, Presynaptic Terminals, Sodium-Potassium-Exchanging ATPase, Spinal Cord, Symporters, Synaptic Transmission
Added April 3, 2018
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17 MeSH Terms
Recent advances in the understanding of severe cutaneous adverse reactions.
Adler NR, Aung AK, Ergen EN, Trubiano J, Goh MSY, Phillips EJ
(2017) Br J Dermatol 177: 1234-1247
MeSH Terms: Allopurinol, Anticonvulsants, Carbamazepine, Cephalosporins, Dideoxynucleosides, Drug Eruptions, Drug Interactions, Herpesviridae Infections, Humans, Leukocytes, Mononuclear, Pharmacogenetics, Prospective Studies, Skin Tests, T-Lymphocytes, Virus Activation, Virus Latency, beta-Lactams
Added March 30, 2020
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MeSH Terms
Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.
Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA
(2015) J Allergy Clin Immunol 136: 262-71.e2
MeSH Terms: Carbamazepine, Dideoxynucleosides, Drug Hypersensitivity, Gene Expression, HLA Antigens, Haptens, Humans, Immunoglobulin E, National Institute of Allergy and Infectious Diseases (U.S.), Practice Guidelines as Topic, Receptors, Antigen, T-Cell, Stevens-Johnson Syndrome, Terminology as Topic, Translational Medical Research, United States, Virus Diseases
Added March 30, 2020
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Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.
White KD, Chung WH, Hung SI, Mallal S, Phillips EJ
(2015) J Allergy Clin Immunol 136: 219-34; quiz 235
MeSH Terms: Allopurinol, B-Lymphocytes, Carbamazepine, Dideoxynucleosides, Drug Hypersensitivity, Gene Expression Regulation, Genetic Loci, HLA Antigens, Humans, Models, Immunological, Pharmacogenetics, Stevens-Johnson Syndrome, T-Lymphocytes, Virus Diseases
Added March 30, 2020
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Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.
Pavlos R, Mallal S, Ostrov D, Pompeu Y, Phillips E
(2014) J Allergy Clin Immunol Pract 2: 21-33
MeSH Terms: Adult, Anticonvulsants, Carbamazepine, Cytomegalovirus, Dideoxynucleosides, Drug Hypersensitivity Syndrome, Exanthema, Female, Fever, HIV-1, HLA Antigens, Herpesvirus 2, Human, Herpesvirus 3, Human, Humans, Prognosis, Reverse Transcriptase Inhibitors, Risk Factors, Severity of Illness Index, Skin Tests, Stevens-Johnson Syndrome, Virus Activation, Viruses
Added March 30, 2020
0 Communities
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Genotyping for severe drug hypersensitivity.
Karlin E, Phillips E
(2014) Curr Allergy Asthma Rep 14: 418
MeSH Terms: Allopurinol, Amoxicillin-Potassium Clavulanate Combination, Carbamazepine, Dideoxynucleosides, Drug Hypersensitivity, Genotype, HLA-B Antigens, Humans, Nevirapine, Pharmacogenetics, Protein Conformation, Stevens-Johnson Syndrome
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms