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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 180

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Calmodulin Mutations Associated with Heart Arrhythmia: A Status Report.
Chazin WJ, Johnson CN
(2020) Int J Mol Sci 21:
MeSH Terms: Arrhythmias, Cardiac, Calcium Signaling, Calmodulin, Humans, Ion Channels, Long QT Syndrome, Myocytes, Cardiac, Ryanodine Receptor Calcium Release Channel, Tachycardia, Ventricular
Added March 11, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.
Perfitt TL, Wang X, Dickerson MT, Stephenson JR, Nakagawa T, Jacobson DA, Colbran RJ
(2020) J Neurosci 40: 2000-2014
MeSH Terms: Animals, Calcium Channels, L-Type, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Nucleus, Gene Expression Regulation, Hippocampus, Mice, Mice, Inbred C57BL, Microfilament Proteins, Nerve Tissue Proteins, Neurons, Signal Transduction
Added March 3, 2020
1 Communities
2 Members
0 Resources
12 MeSH Terms
Delineating the Molecular Basis of the Calmodulin‒bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry-Evidence for a Novel CaM Binding Motif in bMunc13-2.
Piotrowski C, Moretti R, Ihling CH, Haedicke A, Liepold T, Lipstein N, Meiler J, Jahn O, Sinz A
(2020) Cells 9:
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Calmodulin, Cattle, Cross-Linking Reagents, Hydrophobic and Hydrophilic Interactions, Mass Spectrometry, Models, Molecular, Nerve Tissue Proteins, Protein Binding, Protein Domains, Rats, Swine
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Genetic Mosaicism in Calmodulinopathy.
Wren LM, Jiménez-Jáimez J, Al-Ghamdi S, Al-Aama JY, Bdeir A, Al-Hassnan ZN, Kuan JL, Foo RY, Potet F, Johnson CN, Aziz MC, Carvill GL, Kaski JP, Crotti L, Perin F, Monserrat L, Burridge PW, Schwartz PJ, Chazin WJ, Bhuiyan ZA, George AL
(2019) Circ Genom Precis Med 12: 375-385
MeSH Terms: Arrhythmias, Cardiac, Base Sequence, Calcium, Calmodulin, Child, Preschool, Electrophysiology, Female, Genetic Predisposition to Disease, Humans, Infant, Infant, Newborn, Male, Mosaicism, Mutation, Missense, Pedigree
Added March 11, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Activated CaMKII Binds to the mGlu Metabotropic Glutamate Receptor and Modulates Calcium Mobilization.
Marks CR, Shonesy BC, Wang X, Stephenson JR, Niswender CM, Colbran RJ
(2018) Mol Pharmacol 94: 1352-1362
MeSH Terms: Animals, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Calmodulin, Cell Line, Cell Membrane, Female, HEK293 Cells, Humans, Immunoprecipitation, Male, Mice, Mice, Knockout, Protein Binding, Receptor, Metabotropic Glutamate 5, Signal Transduction
Added November 8, 2018
1 Communities
2 Members
0 Resources
16 MeSH Terms
A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.
Johnson CN, Potet F, Thompson MK, Kroncke BM, Glazer AM, Voehler MW, Knollmann BC, George AL, Chazin WJ
(2018) Structure 26: 683-694.e3
MeSH Terms: Binding Sites, Calcium, Calmodulin, Crystallography, X-Ray, Gene Expression Regulation, Humans, Kinetics, Models, Molecular, Mutation, NAV1.5 Voltage-Gated Sodium Channel, Protein Binding
Added March 26, 2019
0 Communities
3 Members
0 Resources
MeSH Terms
A novel mechanism for Ca/calmodulin-dependent protein kinase II targeting to L-type Ca channels that initiates long-range signaling to the nucleus.
Wang X, Marks CR, Perfitt TL, Nakagawa T, Lee A, Jacobson DA, Colbran RJ
(2017) J Biol Chem 292: 17324-17336
MeSH Terms: Animals, Calcium Channels, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Nucleus, Female, Hippocampus, Learning, Memory, Neurons, Protein Domains, Rats, Rats, Sprague-Dawley, Signal Transduction
Added November 13, 2017
0 Communities
3 Members
0 Resources
13 MeSH Terms
Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels.
Walweel K, Gomez-Hurtado N, Oo YW, Beard NA, Dos Remedios C, Johnson CN, Chazin WJ, van Helden DF, Knollmann BC, Laver DR
(2017) J Am Coll Cardiol 70: 115-117
MeSH Terms: Calmodulin, Heart Ventricles, Humans, In Vitro Techniques, Mutation, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Tachycardia, Ventricular
Added March 24, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions.
Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, Leapman RD, Matschinsky FM, Doliba NM, Urs NM, Caron MG, Jacobson DA, Caicedo A, Wess J
(2017) Nat Commun 8: 14295
MeSH Terms: Animals, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Line, Cell Line, Tumor, Diet, High-Fat, Gene Expression, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Signal Transduction, beta-Arrestin 2
Added November 13, 2017
0 Communities
2 Members
0 Resources
16 MeSH Terms
A Novel Human Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.
Stephenson JR, Wang X, Perfitt TL, Parrish WP, Shonesy BC, Marks CR, Mortlock DP, Nakagawa T, Sutcliffe JS, Colbran RJ
(2017) J Neurosci 37: 2216-2233
MeSH Terms: Animals, Autism Spectrum Disorder, Brain, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cells, Cultured, Cycloheximide, Dendrites, Disease Models, Animal, Embryo, Mammalian, Excitatory Postsynaptic Potentials, Exploratory Behavior, Female, Gene Expression Regulation, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Mutation, Rats, Rats, Sprague-Dawley, Receptors, AMPA, Receptors, N-Methyl-D-Aspartate, Sialoglycoproteins, Synaptic Transmission
Added February 2, 2017
1 Communities
2 Members
1 Resources
25 MeSH Terms