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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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Perspective on computational and structural aspects of kinase discovery from IPK2014.
Martin E, Knapp S, Engh RA, Moebitz H, Varin T, Roux B, Meiler J, Berdini V, Baumann A, Vieth M
(2015) Biochim Biophys Acta 1854: 1595-604
MeSH Terms: Amino Acid Sequence, Binding Sites, CSK Tyrosine-Protein Kinase, Computational Biology, Humans, Protein Binding, Protein Conformation, Protein Kinase Inhibitors, Protein Kinases, Proto-Oncogene Proteins c-abl, src-Family Kinases
Added February 5, 2016
1 Communities
2 Members
0 Resources
11 MeSH Terms
Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension.
Dikalov SI, Nazarewicz RR, Bikineyeva A, Hilenski L, Lass├Ęgue B, Griendling KK, Harrison DG, Dikalova AE
(2014) Antioxid Redox Signal 20: 281-94
MeSH Terms: Angiotensin II, Animals, CSK Tyrosine-Protein Kinase, Cyclic N-Oxides, Cytoplasm, Disease Models, Animal, Electron Transport, Endothelial Cells, Gene Silencing, Humans, Hydrogen Peroxide, Hypertension, Malates, Membrane Glycoproteins, Mice, Mice, Knockout, Mitochondria, Heart, NADPH Oxidase 2, NADPH Oxidases, Oxidative Stress, Protein Isoforms, Protein Transport, RNA Interference, Reactive Oxygen Species, Superoxides, src-Family Kinases
Added March 30, 2014
1 Communities
4 Members
0 Resources
26 MeSH Terms
Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions.
Elias BC, Suzuki T, Seth A, Giorgianni F, Kale G, Shen L, Turner JR, Naren A, Desiderio DM, Rao R
(2009) J Biol Chem 284: 1559-69
MeSH Terms: Animals, CSK Tyrosine-Protein Kinase, Caco-2 Cells, Chickens, Dogs, Humans, Hydrogen Peroxide, Mass Spectrometry, Membrane Proteins, Mutation, Missense, Occludin, Oxidants, Phosphoproteins, Phosphorylation, Protein Binding, Protein Structure, Tertiary, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Rats, Tight Junctions, Tyrosine, Zonula Occludens-1 Protein, src-Family Kinases
Added February 25, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.
Weaver AM, Silva CM
(2007) Breast Cancer Res 9: R79
MeSH Terms: Breast Neoplasms, CSK Tyrosine-Protein Kinase, Cell Proliferation, Female, Humans, Luciferases, Luminescent Agents, Neoplasm Proteins, Phosphorylation, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, RNA, Small Interfering, STAT5 Transcription Factor, Signal Transduction, Transfection, src-Family Kinases
Added April 29, 2016
1 Communities
0 Members
0 Resources
16 MeSH Terms
Role of beta-arrestin 1 in the metastatic progression of colorectal cancer.
Buchanan FG, Gorden DL, Matta P, Shi Q, Matrisian LM, DuBois RN
(2006) Proc Natl Acad Sci U S A 103: 1492-7
MeSH Terms: Arrestins, Blotting, Western, CSK Tyrosine-Protein Kinase, Cell Line, Tumor, Cell Membrane, Cell Movement, Collagen, Colorectal Neoplasms, Cytosol, Densitometry, Dinoprostone, Disease Progression, Drug Combinations, ErbB Receptors, Humans, Immunohistochemistry, Immunoprecipitation, Laminin, Microscopy, Fluorescence, Models, Biological, Neoplasm Metastasis, Phosphotyrosine, Protein-Tyrosine Kinases, Proteoglycans, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP4 Subtype, Signal Transduction, Time Factors, Transcriptional Activation, beta-Arrestin 1, beta-Arrestins, src-Family Kinases
Added March 5, 2014
1 Communities
1 Members
0 Resources
32 MeSH Terms
Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.
Schroeder MC, Hamby JM, Connolly CJ, Grohar PJ, Winters RT, Barvian MR, Moore CW, Boushelle SL, Crean SM, Kraker AJ, Driscoll DL, Vincent PW, Elliott WL, Lu GH, Batley BL, Dahring TK, Major TC, Panek RL, Doherty AM, Showalter HD
(2001) J Med Chem 44: 1915-26
MeSH Terms: 3T3 Cells, Animals, Antineoplastic Agents, CSK Tyrosine-Protein Kinase, Cell Division, Colonic Neoplasms, Enzyme Inhibitors, ErbB Receptors, Glioma, Humans, Indicators and Reagents, Kinetics, Mice, Molecular Conformation, Molecular Structure, Phosphorylation, Protein-Tyrosine Kinases, Pyrimidines, Rats, Receptors, Fibroblast Growth Factor, Receptors, Platelet-Derived Growth Factor, Recombinant Proteins, Structure-Activity Relationship, Transfection, Tumor Cells, Cultured, Urea, src-Family Kinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms