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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 132

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Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8 T cells during the primary immune response.
Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH
(2021) Immunity 54: 829-844.e5
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Proliferation, Female, Glycolysis, Immunologic Memory, Listeria monocytogenes, Listeriosis, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Transgenic, Oxidative Phosphorylation, Receptors, Chimeric Antigen, Signal Transduction, Single-Cell Analysis
Added March 26, 2021
3 Communities
1 Members
0 Resources
16 MeSH Terms
CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation.
Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC
(2020) JCI Insight 5:
MeSH Terms: CD28 Antigens, CD8-Positive T-Lymphocytes, Carcinoma, Renal Cell, Gene Expression Regulation, Glucose, Glycolysis, Humans, Interleukin-7, Kidney Neoplasms, Lymphocytes, Tumor-Infiltrating, Mitochondria, Nephritis, Single-Cell Analysis, Tumor Microenvironment
Added August 25, 2020
3 Communities
1 Members
0 Resources
14 MeSH Terms
Osteopontin and iCD8α Cells Promote Intestinal Intraepithelial Lymphocyte Homeostasis.
Nazmi A, Greer MJ, Hoek KL, Piazuelo MB, Weitkamp JH, Olivares-Villagómez D
(2020) J Immunol 204: 1968-1981
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Epithelium, Female, Homeostasis, Humans, Hyaluronan Receptors, Intestines, Intraepithelial Lymphocytes, Killer Cells, Natural, Male, Mice, Mice, Inbred C57BL, Osteopontin, Receptors, Antigen, T-Cell, gamma-delta, Th17 Cells
Added February 28, 2020
1 Communities
1 Members
0 Resources
17 MeSH Terms
CD8 T cells regulate liver injury in obesity-related nonalcoholic fatty liver disease.
Breuer DA, Pacheco MC, Washington MK, Montgomery SA, Hasty AH, Kennedy AJ
(2020) Am J Physiol Gastrointest Liver Physiol 318: G211-G224
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Hepatic Stellate Cells, Hepatitis, Humans, Hyperlipidemias, Interleukin-10, Liver, Male, Mice, Mice, Inbred C57BL, Mice, Obese, Non-alcoholic Fatty Liver Disease, Obesity, Receptors, LDL
Added March 3, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Fluctuations of Spleen Cytokine and Blood Lactate, Importance of Cellular Immunity in Host Defense Against Blood Stage Malaria .
Imai T, Suzue K, Ngo-Thanh H, Ono S, Orita W, Suzuki H, Shimokawa C, Olia A, Obi S, Taniguchi T, Ishida H, Van Kaer L, Murata S, Tanaka K, Hisaeda H
(2019) Front Immunol 10: 2207
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cytokines, Erythrocytes, Female, Immunity, Cellular, Lactates, Macrophages, Malaria, Male, Mice, Inbred C57BL, Mice, Knockout, Parasitemia, Plasmodium yoelii, Spleen
Added March 3, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results.
Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips EJ
(2019) J Allergy Clin Immunol 144: 1413-1416.e7
MeSH Terms: Aged, Anti-HIV Agents, Arthralgia, CD8-Positive T-Lymphocytes, Dideoxynucleosides, Drug Hypersensitivity, Drug-Related Side Effects and Adverse Reactions, Gene Expression Profiling, HLA-B Antigens, Headache, Humans, Immunologic Memory, Lymphocyte Activation, Male, Myalgia, Patch Tests, Single-Cell Analysis, Skin
Added March 30, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8 T cells.
Gemta LF, Siska PJ, Nelson ME, Gao X, Liu X, Locasale JW, Yagita H, Slingluff CL, Hoehn KL, Rathmell JC, Bullock TNJ
(2019) Sci Immunol 4:
MeSH Terms: Animals, Antineoplastic Agents, Immunological, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Glucose, Glucose Transporter Type 1, Glycolysis, Hepatitis A Virus Cellular Receptor 2, Humans, Immunoglobulin G, Immunotherapy, Adoptive, Lymphocytes, Tumor-Infiltrating, Melanoma, Mice, Inbred C57BL, Phosphopyruvate Hydratase, Programmed Cell Death 1 Receptor
Added March 30, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines.
van Montfoort N, Borst L, Korrer MJ, Sluijter M, Marijt KA, Santegoets SJ, van Ham VJ, Ehsan I, Charoentong P, André P, Wagtmann N, Welters MJP, Kim YJ, Piersma SJ, van der Burg SH, van Hall T
(2018) Cell 175: 1744-1755.e15
MeSH Terms: Animals, Antibodies, Neoplasm, Antigens, CD, CD8-Positive T-Lymphocytes, Cancer Vaccines, Cell Line, Tumor, Histocompatibility Antigens Class I, Humans, Immunity, Cellular, Integrin alpha Chains, Mice, NK Cell Lectin-Like Receptor Subfamily C, Neoplasm Proteins, Neoplasms, Experimental, Vaccination
Added December 11, 2020
2 Communities
0 Members
0 Resources
MeSH Terms
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC
(2018) Cell 175: 1780-1795.e19
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Differentiation, Glutaminase, Lymphocyte Activation, Male, Mice, Mice, Transgenic, Th1 Cells, Th17 Cells
Added October 30, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
Quantitative assessment of cell population diversity in single-cell landscapes.
Liu Q, Herring CA, Sheng Q, Ping J, Simmons AJ, Chen B, Banerjee A, Li W, Gu G, Coffey RJ, Shyr Y, Lau KS
(2018) PLoS Biol 16: e2006687
MeSH Terms: Animals, Brain, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cluster Analysis, Computer Simulation, Databases, Nucleic Acid, Gene Expression Profiling, Humans, Intestinal Mucosa, Mice, Mice, Inbred C57BL, Models, Biological, Neoplasms, Experimental, Oligodendroglia, Sequence Analysis, RNA, Single-Cell Analysis, Software, Workflow
Added December 4, 2020
1 Communities
0 Members
0 Resources
MeSH Terms