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Results: 1 to 10 of 167

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Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy.
Barone SM, Paul AG, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM
(2021) Elife 10:
MeSH Terms: Adolescent, Adult, Algorithms, CD4-Positive T-Lymphocytes, COVID-19, Humans, Leukemia, Myeloid, Acute, Melanoma, Neoplasms, Picornaviridae Infections, Rhinovirus, SARS-CoV-2, Unsupervised Machine Learning, Young Adult
Added August 31, 2021
3 Communities
1 Members
0 Resources
MeSH Terms
HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior.
Senosain MF, Zou Y, Novitskaya T, Vasiukov G, Balar AB, Rowe DJ, Doxie DB, Lehman JM, Eisenberg R, Maldonado F, Zijlstra A, Novitskiy SV, Irish JM, Massion PP
(2021) Sci Rep 11: 14424
MeSH Terms: Adenocarcinoma of Lung, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, HLA-DR Antigens, Humans, Leukocytes, Mononuclear
Added August 31, 2021
3 Communities
1 Members
0 Resources
6 MeSH Terms
PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic Autoimmunity.
Haycook CP, Balsamo JA, Glass EB, Williams CH, Hong CC, Major AS, Giorgio TD
(2020) Int J Nanomedicine 15: 1215-1228
MeSH Terms: Animals, Autoimmunity, CD4-Positive T-Lymphocytes, Cytokines, Drug Delivery Systems, Female, Hedgehog Proteins, Immunoglobulin Fragments, Immunologic Factors, Mice, Inbred C57BL, Nanoparticles, Polylactic Acid-Polyglycolic Acid Copolymer, Pyrimidinones, Rheumatic Diseases, T-Lymphocytes, T-Lymphocytes, Helper-Inducer, Thiophenes
Added March 30, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Osteopontin and iCD8╬▒ Cells Promote Intestinal Intraepithelial Lymphocyte Homeostasis.
Nazmi A, Greer MJ, Hoek KL, Piazuelo MB, Weitkamp JH, Olivares-Villag├│mez D
(2020) J Immunol 204: 1968-1981
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Epithelium, Female, Homeostasis, Humans, Hyaluronan Receptors, Intestines, Intraepithelial Lymphocytes, Killer Cells, Natural, Male, Mice, Mice, Inbred C57BL, Osteopontin, Receptors, Antigen, T-Cell, gamma-delta, Th17 Cells
Added February 28, 2020
1 Communities
1 Members
0 Resources
17 MeSH Terms
Fluctuations of Spleen Cytokine and Blood Lactate, Importance of Cellular Immunity in Host Defense Against Blood Stage Malaria .
Imai T, Suzue K, Ngo-Thanh H, Ono S, Orita W, Suzuki H, Shimokawa C, Olia A, Obi S, Taniguchi T, Ishida H, Van Kaer L, Murata S, Tanaka K, Hisaeda H
(2019) Front Immunol 10: 2207
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cytokines, Erythrocytes, Female, Immunity, Cellular, Lactates, Macrophages, Malaria, Male, Mice, Inbred C57BL, Mice, Knockout, Parasitemia, Plasmodium yoelii, Spleen
Added March 3, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses.
Grifoni A, Moore E, Voic H, Sidney J, Phillips E, Jadi R, Mallal S, De Silva AD, De Silva AM, Peters B, Weiskopf D, Sette A
(2019) Front Immunol 10: 1568
MeSH Terms: Alleles, Antibody Specificity, CD4-Positive T-Lymphocytes, Dengue, Dengue Virus, Epitopes, T-Lymphocyte, HLA-DP Antigens, HLA-DRB1 Chains, Humans, Interferon-gamma
Added March 30, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
A case report of clonal EBV-like memory CD4 T cell activation in fatal checkpoint inhibitor-induced encephalitis.
Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi C, Xu Y, Moslehi JJ, Sanders ME, Sosman JA, Balko JM
(2019) Nat Med 25: 1243-1250
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, CD4-Positive T-Lymphocytes, Encephalitis, Female, Herpesvirus 4, Human, Humans, Immunologic Memory, Lymphocyte Activation, Male, Middle Aged, Programmed Cell Death 1 Receptor, Young Adult
Added November 12, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Widespread Tau-Specific CD4 T Cell Reactivity in the General Population.
Lindestam Arlehamn CS, Pham J, Alcalay RN, Frazier A, Shorr E, Carpenter C, Sidney J, Dhanwani R, Agin-Liebes J, Garretti F, Amara AW, Standaert DG, Phillips EJ, Mallal SA, Peters B, Sulzer D, Sette A
(2019) J Immunol 203: 84-92
MeSH Terms: Adult, Aged, Aged, 80 and over, Autoimmunity, CD4-Positive T-Lymphocytes, Cells, Cultured, Clonal Selection, Antigen-Mediated, Female, Humans, Immune Tolerance, Male, Middle Aged, Peptides, Phosphorylation, Protein Aggregation, Pathological, T-Cell Antigen Receptor Specificity, Young Adult, tau Proteins
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
IgG4-related disease: Association with a rare gene variant expressed in cytotoxic T cells.
Newman JH, Shaver A, Sheehan JH, Mallal S, Stone JH, Pillai S, Bastarache L, Riebau D, Allard-Chamard H, Stone WM, Perugino C, Pilkinton M, Smith SA, McDonnell WJ, Capra JA, Meiler J, Cogan J, Xing K, Mahajan VS, Mattoo H, Hamid R, Phillips JA, Undiagnosed Disease Network
(2019) Mol Genet Genomic Med 7: e686
MeSH Terms: Adolescent, CD4-Positive T-Lymphocytes, Genetic Variation, Humans, Immunoglobulin G, Immunoglobulin G4-Related Disease, Male, Middle Aged, T-Lymphocytes, Cytotoxic
Added March 3, 2020
0 Communities
2 Members
0 Resources
9 MeSH Terms
Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR
(2019) Proc Natl Acad Sci U S A 116: 8975-8984
MeSH Terms: Animals, Antibody Formation, B-Lymphocytes, Basic Helix-Loop-Helix Transcription Factors, CD4-Positive T-Lymphocytes, Cell Hypoxia, Cytokines, Germinal Center, Humans, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Immunity, Humoral, Immunization, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Transgenic, Receptors, CXCR5, Sheep, T-Lymphocytes, Helper-Inducer
Added April 23, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms