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Results: 1 to 10 of 11

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Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects.
Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR
(2019) J Biomed Mater Res B Appl Biomater 107: 1491-1503
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Calcium Phosphates, Drug Delivery Systems, Durapatite, Humans, Mandible, Mandibular Injuries, Recombinant Proteins, Swine, Swine, Miniature, Tomography, X-Ray Computed
Added March 20, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Fabrication of Trabecular Bone-Templated Tissue-Engineered Constructs by 3D Inkjet Printing.
Vanderburgh JP, Fernando SJ, Merkel AR, Sterling JA, Guelcher SA
(2017) Adv Healthc Mater 6:
MeSH Terms: Biocompatible Materials, Bone Regeneration, Cancellous Bone, Cartilage, Cell Differentiation, Cells, Cultured, Humans, Materials Testing, Mesenchymal Stem Cells, Osteogenesis, Printing, Three-Dimensional, Tissue Engineering, Tissue Scaffolds
Added March 21, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice.
de la Croix Ndong J, Stevens DM, Vignaux G, Uppuganti S, Perrien DS, Yang X, Nyman JS, Harth E, Elefteriou F
(2015) J Bone Miner Res 30: 55-63
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Cell Differentiation, Disease Models, Animal, Drug Delivery Systems, Humans, MAP Kinase Kinase Kinases, Mesenchymal Stem Cells, Mice, Mice, Knockout, Nanoparticles, Neurofibromatosis 1, Neurofibromin 1, Protein Kinase Inhibitors, Pseudarthrosis, Pyridones, Pyrimidinones
Added July 28, 2014
2 Communities
7 Members
0 Resources
18 MeSH Terms
Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical-sized segmental defect in rat femora.
Yoshii T, Hafeman AE, Esparza JM, Okawa A, Gutierrez G, Guelcher SA
(2014) J Tissue Eng Regen Med 8: 589-95
MeSH Terms: Animals, Biocompatible Materials, Bone Regeneration, Cell Line, Disease Models, Animal, Femur, Injections, Kinetics, Lovastatin, Mice, Microspheres, Polyurethanes, Rats, Tissue Scaffolds, X-Ray Microtomography
Added February 23, 2016
1 Communities
1 Members
0 Resources
15 MeSH Terms
Injectable reactive biocomposites for bone healing in critical-size rabbit calvarial defects.
Dumas JE, BrownBaer PB, Prieto EM, Guda T, Hale RG, Wenke JC, Guelcher SA
(2012) Biomed Mater 7: 024112
MeSH Terms: Animals, Bone Regeneration, Bone Substitutes, Fracture Healing, Guided Tissue Regeneration, Injections, Polyurethanes, Rabbits, Skull Fractures, Treatment Outcome
Added February 23, 2016
1 Communities
1 Members
0 Resources
10 MeSH Terms
Improving bone formation in a rat femur segmental defect by controlling bone morphogenetic protein-2 release.
Brown KV, Li B, Guda T, Perrien DS, Guelcher SA, Wenke JC
(2011) Tissue Eng Part A 17: 1735-46
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Cattle, Collagen, Femur, Humans, Implants, Experimental, Kinetics, Lactic Acid, Microspheres, Osteogenesis, Polyglycolic Acid, Polylactic Acid-Polyglycolic Acid Copolymer, Polyurethanes, Rats, Recombinant Proteins, Tissue Scaffolds, Tomography, X-Ray Computed, Transforming Growth Factor beta
Added April 25, 2013
1 Communities
3 Members
0 Resources
20 MeSH Terms
A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration.
Yoshii T, Hafeman AE, Nyman JS, Esparza JM, Shinomiya K, Spengler DM, Mundy GR, Gutierrez GE, Guelcher SA
(2010) Tissue Eng Part A 16: 2369-79
MeSH Terms: Animals, Biocompatible Materials, Bone Regeneration, Bone and Bones, Cell Differentiation, Delayed-Action Preparations, Elastomers, Kinetics, Lovastatin, Male, Mice, Microscopy, Electron, Scanning, Osteogenesis, Polyurethanes, Rats, Rats, Sprague-Dawley, Tissue Scaffolds
Added March 24, 2014
1 Communities
2 Members
0 Resources
17 MeSH Terms
Regenerative effects of transplanted mesenchymal stem cells in fracture healing.
Granero-Moltó F, Weis JA, Miga MI, Landis B, Myers TJ, O'Rear L, Longobardi L, Jansen ED, Mortlock DP, Spagnoli A
(2009) Stem Cells 27: 1887-98
MeSH Terms: Animals, Animals, Genetically Modified, Bone Morphogenetic Protein 2, Bone Regeneration, Bony Callus, Female, Fracture Healing, Humans, Luminescent Proteins, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells, Mice, Receptors, CXCR4, Tibial Fractures
Added June 9, 2010
1 Communities
2 Members
0 Resources
14 MeSH Terms
Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration.
Hafeman AE, Li B, Yoshii T, Zienkiewicz K, Davidson JM, Guelcher SA
(2008) Pharm Res 25: 2387-99
MeSH Terms: Absorbable Implants, Animals, Biomechanical Phenomena, Bone Regeneration, Cell Line, Cross-Linking Reagents, Drug Carriers, Elasticity, Hydrolysis, Injections, Subcutaneous, Isocyanates, Kinetics, Male, Mice, Osteoblasts, Platelet-Derived Growth Factor, Polyurethanes, Porosity, Rats, Rats, Sprague-Dawley, Solubility, Temperature, Tissue Engineering, Tissue Scaffolds
Added December 10, 2013
1 Communities
2 Members
0 Resources
24 MeSH Terms
A novel rat model for the study of deficits in bone formation in type-2 diabetes.
Liu Z, Aronson J, Wahl EC, Liu L, Perrien DS, Kern PA, Fowlkes JL, Thrailkill KM, Bunn RC, Cockrell GE, Skinner RA, Lumpkin CK
(2007) Acta Orthop 78: 46-55
MeSH Terms: Animals, Bone Density, Bone Regeneration, Bone and Bones, Cell Proliferation, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Immunohistochemistry, Models, Biological, Osteogenesis, Rats, Rats, Zucker, Tibia
Added April 25, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms