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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 136

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Tuning Ligand Density To Optimize Pharmacokinetics of Targeted Nanoparticles for Dual Protection against Tumor-Induced Bone Destruction.
Vanderburgh J, Hill JL, Gupta MK, Kwakwa KA, Wang SK, Moyer K, Bedingfield SK, Merkel AR, d'Arcy R, Guelcher SA, Rhoades JA, Duvall CL
(2020) ACS Nano 14: 311-327
MeSH Terms: Animals, Antineoplastic Agents, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Disease Models, Animal, Drug Screening Assays, Antitumor, Female, Humans, Ligands, Mice, Mice, Inbred C57BL, Mice, Knockout, Nanoparticles, Optical Imaging, Particle Size, Polymers, Pyridines, Surface Properties, Thiophenes, X-Ray Microtomography
Added March 19, 2020
0 Communities
3 Members
0 Resources
21 MeSH Terms
PREX1 drives spontaneous bone dissemination of ER+ breast cancer cells.
Clements ME, Johnson RW
(2020) Oncogene 39: 1318-1334
MeSH Terms: Animals, Apoptosis, Biomarkers, Tumor, Bone Neoplasms, Breast Neoplasms, Cell Movement, Cell Proliferation, Female, Gene Expression Regulation, Neoplastic, Guanine Nucleotide Exchange Factors, Humans, Mice, Mice, Nude, Receptors, Estrogen, Tumor Cells, Cultured, Xenograft Model Antitumor Assays
Added March 3, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.
Vanderburgh JP, Kwakwa KA, Werfel TA, Merkel AR, Gupta MK, Johnson RW, Guelcher SA, Duvall CL, Rhoades JA
(2019) J Control Release 311-312: 257-272
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Cell Survival, Drug Carriers, Drug Liberation, Female, Gene Expression Regulation, Neoplastic, Humans, Mammary Neoplasms, Animal, Mesenchymal Stem Cells, Mice, Inbred C57BL, Mice, Knockout, Mice, Nude, Nanoparticles, Osteogenesis, Polymers, Pyridines, Thiophenes, Zinc Finger Protein Gli2
Added March 3, 2020
0 Communities
4 Members
0 Resources
23 MeSH Terms
Breast Cancer Dormancy in Bone.
Clements ME, Johnson RW
(2019) Curr Osteoporos Rep 17: 353-361
MeSH Terms: Animals, Bone Marrow, Bone Neoplasms, Breast Neoplasms, Disease Models, Animal, Disease Progression, Female, Humans, Mice, Neoplasm Metastasis, Signal Transduction, Tumor Microenvironment
Added March 3, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Multiple actions of parathyroid hormone-related protein in breast cancer bone metastasis.
Martin TJ, Johnson RW
(2021) Br J Pharmacol 178: 1923-1935
MeSH Terms: Bone Neoplasms, Bone and Bones, Humans, Osteoclasts, Parathyroid Hormone, Parathyroid Hormone-Related Protein
Added March 3, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Early TGF-β inhibition in mice reduces the incidence of breast cancer induced bone disease in a myeloid dependent manner.
Buenrostro D, Kwakwa KA, Putnam NE, Merkel AR, Johnson JR, Cassat JE, Sterling JA
(2018) Bone 113: 77-88
MeSH Terms: Animals, Bone Neoplasms, Female, Humans, Mammary Neoplasms, Experimental, Mice, Mice, Knockout, Myeloid Progenitor Cells, Transforming Growth Factor beta, Tumor Microenvironment
Added April 15, 2019
0 Communities
2 Members
0 Resources
10 MeSH Terms
Simple staging system for osteosarcoma performs equivalently to the AJCC and MSTS systems.
Cates JMM
(2018) J Orthop Res 36: 2802-2808
MeSH Terms: Adolescent, Adult, Bone Neoplasms, Bone and Bones, Female, Humans, Male, Neoplasm Metastasis, Neoplasm Staging, Osteosarcoma, Prognosis, Retrospective Studies, SEER Program, United States, Young Adult
Added November 1, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
3D bone models to study the complex physical and cellular interactions between tumor and the bone microenvironment.
Vanderburgh JP, Guelcher SA, Sterling JA
(2018) J Cell Biochem 119: 5053-5059
MeSH Terms: Animals, Bone Neoplasms, Bone and Bones, Cellular Microenvironment, Humans, Models, Biological, Tissue Engineering, Tissue Scaffolds, Tumor Microenvironment
Added April 15, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
Modeling Continuous Prognostic Factors in Survival Analysis: Implications for Tumor Staging and Assessing Chemotherapy Effect in Osteosarcoma.
Cates JMM
(2018) Am J Surg Pathol 42: 485-491
MeSH Terms: Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Bone Neoplasms, Chemotherapy, Adjuvant, Child, Databases, Factual, Decision Support Techniques, Female, Humans, Male, Middle Aged, Models, Statistical, Necrosis, Neoadjuvant Therapy, Neoplasm Staging, Orthopedic Procedures, Osteosarcoma, Predictive Value of Tests, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome, Tumor Burden, United States, Young Adult
Added November 1, 2018
0 Communities
1 Members
0 Resources
28 MeSH Terms
Hallmarks of Bone Metastasis.
Johnson RW, Suva LJ
(2018) Calcif Tissue Int 102: 141-151
MeSH Terms: Animals, Bone Marrow Cells, Bone Neoplasms, Bone and Bones, Breast Neoplasms, Female, Humans, Mice, Osteoblasts, Osteoclasts, Osteolysis
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms