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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 34

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Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K.
Elajaili HB, Hernandez-Lagunas L, Ranguelova K, Dikalov S, Nozik-Grayck E
(2019) J Vis Exp :
MeSH Terms: Animals, Antimycin A, Bleomycin, Bronchoalveolar Lavage Fluid, Cattle, Cell Compartmentation, Electron Spin Resonance Spectroscopy, Lung, Mice, Mitochondria, Oxidation-Reduction, RAW 264.7 Cells, Superoxides, Temperature
Added March 26, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
PD-1 up-regulation on CD4 T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP
(2018) Sci Transl Med 10:
MeSH Terms: Adult, Aged, Animals, Bleomycin, CD4-Positive T-Lymphocytes, Cell Proliferation, Collagen Type I, Disease Models, Animal, Female, Fibroblasts, Gene Expression Regulation, Humans, Idiopathic Pulmonary Fibrosis, Interleukin-17, Male, Mice, Middle Aged, Programmed Cell Death 1 Receptor, RNA, Messenger, STAT3 Transcription Factor, Sarcoidosis, Th17 Cells, Transforming Growth Factor beta1, Up-Regulation
Added March 26, 2019
0 Communities
1 Members
0 Resources
24 MeSH Terms
Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome.
Young LR, Gulleman PM, Short CW, Tanjore H, Sherrill T, Qi A, McBride AP, Zaynagetdinov R, Benjamin JT, Lawson WE, Novitskiy SV, Blackwell TS
(2016) JCI Insight 1: e88947
MeSH Terms: Animals, Bleomycin, Chemokine CCL2, Disease Susceptibility, Epithelial Cells, Female, Hermanski-Pudlak Syndrome, Macrophages, Male, Mice, Mice, Inbred C57BL, Protein Serine-Threonine Kinases, Pulmonary Alveoli, Pulmonary Fibrosis, Receptor, Transforming Growth Factor-beta Type II, Receptors, CCR2, Receptors, Transforming Growth Factor beta, Transforming Growth Factor beta
Added March 29, 2017
1 Communities
2 Members
0 Resources
18 MeSH Terms
Bleomycin induced epithelial-mesenchymal transition (EMT) in pleural mesothelial cells.
Chen LJ, Ye H, Zhang Q, Li FZ, Song LJ, Yang J, Mu Q, Rao SS, Cai PC, Xiang F, Zhang JC, Su Y, Xin JB, Ma WL
(2015) Toxicol Appl Pharmacol 283: 75-82
MeSH Terms: Animals, Antibiotics, Antineoplastic, Bleomycin, Cell Line, Dose-Response Relationship, Drug, Epithelial-Mesenchymal Transition, Epithelium, Humans, Lung, Male, Mice, Mice, Inbred C57BL, Respiratory Mucosa
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.
Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2013) Am J Respir Crit Care Med 187: 630-9
MeSH Terms: Animals, Bleomycin, Disease Models, Animal, Epithelium, In Situ Nick-End Labeling, Lung Injury, Mice, Mice, Transgenic, Pulmonary Alveoli, Pulmonary Fibrosis, Wound Healing, beta Catenin
Added March 5, 2014
1 Communities
2 Members
0 Resources
12 MeSH Terms
The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.
Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX
(2012) Am J Respir Crit Care Med 186: 1014-24
MeSH Terms: Adaptor Protein Complex 3, Animals, Bleomycin, Genetic Predisposition to Disease, Hermanski-Pudlak Syndrome, Humans, Lung, Macrophage Activation, Macrophages, Alveolar, Mice, Mice, Knockout, Mutation, Protein Transport, Pulmonary Alveoli, Pulmonary Fibrosis, Respiratory Mucosa
Added March 5, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice.
Polosukhin VV, Degryse AL, Newcomb DC, Jones BR, Ware LB, Lee JW, Loyd JE, Blackwell TS, Lawson WE
(2012) Exp Lung Res 38: 135-46
MeSH Terms: Airway Obstruction, Airway Remodeling, Animals, Antibiotics, Antineoplastic, Bleomycin, Disease Models, Animal, Epithelial Cells, Female, Fibroblasts, Humans, Idiopathic Pulmonary Fibrosis, Inflammation, Lung, Male, Mice, Mice, Inbred C57BL, S100 Calcium-Binding Protein A4, S100 Proteins, Transforming Growth Factor beta1, Transforming Growth Factor beta2
Added March 5, 2014
1 Communities
3 Members
0 Resources
20 MeSH Terms
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice.
Degryse AL, Xu XC, Newman JL, Mitchell DB, Tanjore H, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Phillips JA, Cogan JD, Blackwell TS, Lawson WE
(2012) Exp Lung Res 38: 124-34
MeSH Terms: Airway Remodeling, Animals, Antibiotics, Antineoplastic, Bleomycin, Collagen, Epithelial Cells, Female, Idiopathic Pulmonary Fibrosis, Leukocytes, Lung, Male, Mice, Mice, Inbred C57BL, Mutation, Pneumonia, Pulmonary Alveoli, RNA, Telomerase, Telomere Homeostasis, Telomere Shortening
Added March 5, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis.
Tanjore H, Blackwell TS, Lawson WE
(2012) Am J Physiol Lung Cell Mol Physiol 302: L721-9
MeSH Terms: Aging, Animals, Apoptosis, Bleomycin, Endoplasmic Reticulum Stress, Epithelial-Mesenchymal Transition, Humans, Idiopathic Pulmonary Fibrosis, Inflammation, Mice, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein C, Smoking, Unfolded Protein Response
Added March 5, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression.
Zhou W, Dowell DR, Geraci MW, Blackwell TS, Collins RD, Polosukhin VV, Lawson WE, Wu P, Sussan T, Biswal S, Goleniewska K, O'Neal J, Newcomb DC, Toki S, Morrow JD, Peebles RS
(2011) Am J Physiol Lung Cell Mol Physiol 301: L615-22
MeSH Terms: Acute Lung Injury, Animals, Apoptosis, Bleomycin, Bronchoalveolar Lavage Fluid, Epoprostenol, F2-Isoprostanes, Female, Gas Chromatography-Mass Spectrometry, Gene Expression, Humans, Immunohistochemistry, Lung, Mice, Mice, Transgenic, NAD(P)H Dehydrogenase (Quinone), Polymerase Chain Reaction, Prostaglandin-Endoperoxide Synthases, Reactive Oxygen Species, Receptors, Epoprostenol, Respiratory Function Tests, Respiratory Mucosa, Signal Transduction, Survival Rate
Added March 5, 2014
1 Communities
2 Members
0 Resources
24 MeSH Terms