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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Phage-display-guided nanocarrier targeting to atheroprone vasculature.
Hofmeister LH, Lee SH, Norlander AE, Montaniel KR, Chen W, Harrison DG, Sung HJ
(2015) ACS Nano 9: 4435-46
MeSH Terms: Amino Acid Sequence, Animals, Apolipoproteins E, Atherosclerosis, Biopterin, Carotid Arteries, Disease Susceptibility, Drug Carriers, Male, Mice, Molecular Sequence Data, Nanomedicine, Nanostructures, Oligopeptides, Peptide Library
Added March 31, 2015
1 Communities
1 Members
0 Resources
15 MeSH Terms
Methotrexate-mediated inhibition of nuclear factor κB activation by distinct pathways in T cells and fibroblast-like synoviocytes.
Spurlock CF, Gass HM, Bryant CJ, Wells BC, Olsen NJ, Aune TM
(2015) Rheumatology (Oxford) 54: 178-87
MeSH Terms: Adult, Aged, Apoptosis, Arthritis, Rheumatoid, Biopterin, Case-Control Studies, Cell Line, Female, Fibroblasts, Humans, Jurkat Cells, MAP Kinase Kinase 4, Male, Methotrexate, Middle Aged, NF-kappa B, Reactive Oxygen Species, Signal Transduction, Synovial Membrane
Added January 21, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK.
Spurlock CF, Aune ZT, Tossberg JT, Collins PL, Aune JP, Huston JW, Crooke PS, Olsen NJ, Aune TM
(2011) Arthritis Rheum 63: 2606-16
MeSH Terms: Adult, Antirheumatic Agents, Apoptosis, Arthritis, Rheumatoid, Biopterin, Cell Line, Tumor, Gene Expression, Humans, JNK Mitogen-Activated Protein Kinases, Methotrexate, Middle Aged, Reactive Oxygen Species, Tumor Cells, Cultured
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Loss of NRF2 impairs gastric nitrergic stimulation and function.
Mukhopadhyay S, Sekhar KR, Hale AB, Channon KM, Farrugia G, Freeman ML, Gangula PR
(2011) Free Radic Biol Med 51: 619-25
MeSH Terms: Animals, Antioxidants, Biopterin, Chloramphenicol O-Acetyltransferase, Disease Models, Animal, Down-Regulation, Gastric Emptying, Gastric Mucosa, Gastroparesis, Glutamate-Cysteine Ligase, Humans, Mice, Mice, Knockout, Muscle Relaxation, NF-E2-Related Factor 2, Nitrergic Neurons, Stomach, Superoxide Dismutase, Superoxide Dismutase-1, Vasomotor System
Added March 13, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation.
Chen W, Li L, Brod T, Saeed O, Thabet S, Jansen T, Dikalov S, Weyand C, Goronzy J, Harrison DG
(2011) J Biol Chem 286: 13846-51
MeSH Terms: Animals, Biopterin, CD3 Complex, Cytokines, GTP Cyclohydrolase, Gene Expression Regulation, Enzymologic, Humans, Immunologic Memory, Mice, Mice, Inbred C57BL, Mice, Transgenic, Ovalbumin, Oxygen, Phosphorylation, T-Lymphocytes
Added December 10, 2013
1 Communities
2 Members
0 Resources
15 MeSH Terms
Regulation of endothelial cell tetrahydrobiopterin pathophysiological and therapeutic implications.
Harrison DG, Chen W, Dikalov S, Li L
(2010) Adv Pharmacol 60: 107-32
MeSH Terms: Animals, Biopterin, Endothelial Cells, Humans
Added December 10, 2013
1 Communities
2 Members
0 Resources
4 MeSH Terms
Safety of sapropterin dihydrochloride (6r-bh4) in patients with pulmonary hypertension.
Robbins IM, Hemnes AR, Gibbs JS, Christman BW, Howard L, Meehan S, Cabrita I, Gonzalez R, Oyler T, Zhao L, Du RH, Mendes LA, Wilkins MR
(2011) Exp Lung Res 37: 26-34
MeSH Terms: Administration, Oral, Adult, Antihypertensive Agents, Biomarkers, Biopterin, Chemokine CCL2, Drug Therapy, Combination, Endothelin Receptor Antagonists, Exercise Test, Exercise Tolerance, Female, Humans, Hypertension, Pulmonary, London, Male, Middle Aged, Natriuretic Peptide, Brain, Nitric Oxide, Oxidative Stress, Peptide Fragments, Phosphodiesterase 5 Inhibitors, Piperazines, Purines, Recovery of Function, Sildenafil Citrate, Sulfones, Tennessee, Time Factors, Treatment Outcome, Walking
Added February 19, 2015
0 Communities
2 Members
0 Resources
30 MeSH Terms
Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction.
Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC
(2010) Circulation 121: 519-28
MeSH Terms: Animals, Biopterin, Calcium-Binding Proteins, Desoxycorticosterone, Disease Models, Animal, Heart Failure, Diastolic, Hypertension, Male, Mice, Mice, Inbred C57BL, Myocardium, Nephrectomy, Nitric Oxide, Nitric Oxide Synthase, Oxygen, Peptidyl-Dipeptidase A, Superoxides, Ventricular Dysfunction, Left
Added December 10, 2013
1 Communities
2 Members
0 Resources
18 MeSH Terms
GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.
Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W
(2010) Circ Res 106: 328-36
MeSH Terms: Animals, Binding Sites, Biopterin, Blotting, Western, Carotid Arteries, Casein Kinase II, Cell Line, Cells, Cultured, Endothelial Cells, Enzyme Inhibitors, GTP Cyclohydrolase, Humans, Intracellular Signaling Peptides and Proteins, Mice, Mice, Inbred C57BL, Mutation, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Synthase Type III, Phosphorylation, RNA Interference, Stress, Mechanical
Added December 10, 2013
1 Communities
1 Members
0 Resources
22 MeSH Terms
Targeted detoxification of selected reactive oxygen species in the vascular endothelium.
Shuvaev VV, Christofidou-Solomidou M, Bhora F, Laude K, Cai H, Dikalov S, Arguiri E, Solomides CC, Albelda SM, Harrison DG, Muzykantov VR
(2009) J Pharmacol Exp Ther 331: 404-11
MeSH Terms: Angiotensin II, Animals, Antibodies, Antioxidants, Biopterin, Bronchoalveolar Lavage Fluid, Catalase, Cross-Linking Reagents, Endothelium, Vascular, Glucose Oxidase, Hydrogen Peroxide, Lung Diseases, Mice, Mice, Inbred C57BL, Oxidative Stress, Platelet Endothelial Cell Adhesion Molecule-1, Pulmonary Circulation, Reactive Oxygen Species, Reperfusion Injury, Superoxide Dismutase, Superoxides
Added February 17, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms