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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials.
Wang Y, Ayres KL, Goldman DA, Dickler MN, Bardia A, Mayer IA, Winer E, Fredrickson J, Arteaga CL, Baselga J, Manning HC, Mahmood U, Ulaner GA
(2017) Clin Cancer Res 23: 3053-3060
MeSH Terms: Adult, Aged, Biomarkers, Pharmacological, Breast Neoplasms, Cinnamates, Dose-Response Relationship, Drug, Estradiol, Estrogen Receptor alpha, Female, Fulvestrant, Humans, Indazoles, Middle Aged, Molecular Imaging, Molecular Targeted Therapy, Positron Emission Tomography Computed Tomography, Receptors, Estrogen, Tamoxifen
Added April 6, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update.
Saito Y, Stamp LK, Caudle KE, Hershfield MS, McDonagh EM, Callaghan JT, Tassaneeyakul W, Mushiroda T, Kamatani N, Goldspiel BR, Phillips EJ, Klein TE, Lee MT, Clinical Pharmacogenetics Implementation Consortium
(2016) Clin Pharmacol Ther 99: 36-7
MeSH Terms: Allopurinol, Biomarkers, Pharmacological, Drug Administration Schedule, Genotype, Guidelines as Topic, HLA-B Antigens, Humans
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients.
McLaughlin B, Gidday JM
(2013) Transl Stroke Res 4: 104-13
MeSH Terms: Biomarkers, Pharmacological, Clinical Trials as Topic, Humans, Neuroprotective Agents, Stroke, Translational Medical Research
Added January 26, 2015
1 Communities
1 Members
0 Resources
6 MeSH Terms
Biomarkers of response to Akt inhibitor MK-2206 in breast cancer.
Sangai T, Akcakanat A, Chen H, Tarco E, Wu Y, Do KA, Miller TW, Arteaga CL, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F
(2012) Clin Cancer Res 18: 5816-28
MeSH Terms: Animals, Apoptosis, Biomarkers, Pharmacological, Breast Neoplasms, Cell Line, Tumor, Class I Phosphatidylinositol 3-Kinases, Drug Synergism, Female, Heterocyclic Compounds, 3-Ring, Humans, In Vitro Techniques, Mice, Oncogene Protein v-akt, PTEN Phosphohydrolase, Paclitaxel, Phosphatidylinositol 3-Kinases, Protein Kinase Inhibitors, Transplantation, Heterologous
Added September 3, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
HLA and pharmacogenetics of drug hypersensitivity.
Pavlos R, Mallal S, Phillips E
(2012) Pharmacogenomics 13: 1285-306
MeSH Terms: Alleles, Biomarkers, Pharmacological, Drug Hypersensitivity, Drug-Related Side Effects and Adverse Reactions, HLA Antigens, Humans, Pharmacogenetics, Stevens-Johnson Syndrome
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genome-wide approaches in pharmacogenomics: heritability estimation and pharmacoethnicity as primary challenges.
Gamazon ER, Perera M
(2012) Pharmacogenomics 13: 1101-4
MeSH Terms: Biomarkers, Pharmacological, Ethnic Groups, Genetic Variation, Genome, Human, Genome-Wide Association Study, Humans, Pharmacogenetics
Added April 13, 2017
0 Communities
1 Members
0 Resources
7 MeSH Terms
The limits of genome-wide methods for pharmacogenomic testing.
Gamazon ER, Skol AD, Perera MA
(2012) Pharmacogenet Genomics 22: 261-72
MeSH Terms: Biomarkers, Pharmacological, Databases, Genetic, European Continental Ancestry Group, Genetic Association Studies, Genetic Variation, Genome, Human, Genotype, HapMap Project, Humans, Inactivation, Metabolic, Linkage Disequilibrium, Pharmacogenetics, Polymorphism, Single Nucleotide
Added April 13, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network Study.
Irvin MR, Zhang Q, Kabagambe EK, Perry RT, Straka RJ, Tiwari HK, Borecki IB, Shimmin LC, Stuart C, Zhong Y, Hixson JE, Arnett DK
(2012) Pharmacogenet Genomics 22: 367-72
MeSH Terms: Adult, Biomarkers, Pharmacological, Cholesterol, HDL, Cholesterol, LDL, Clinical Trials as Topic, Female, Fenofibrate, Gene Frequency, Genetic Association Studies, Haplotypes, Humans, Hypolipidemic Agents, Linkage Disequilibrium, Male, Middle Aged, PPAR alpha, Triglycerides
Added March 7, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis.
Man M, Close SL, Shaw AD, Bernard GR, Douglas IS, Kaner RJ, Payen D, Vincent JL, Fossceco S, Janes JM, Leishman AG, O'Brien L, Williams MD, Garcia JG
(2013) Pharmacogenomics J 13: 218-26
MeSH Terms: Biomarkers, Pharmacological, Disease Progression, Epistasis, Genetic, Genetic Markers, Genome-Wide Association Study, Humans, Polymorphism, Single Nucleotide, Prognosis, Protein C, Randomized Controlled Trials as Topic, Recombinant Proteins, Sepsis
Added October 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Copy number polymorphisms and anticancer pharmacogenomics.
Gamazon ER, Huang RS, Dolan ME, Cox NJ
(2011) Genome Biol 12: R46
MeSH Terms: Antineoplastic Agents, Biomarkers, Pharmacological, Carboplatin, Cell Line, Tumor, Cisplatin, Daunorubicin, Etoposide, Gene Dosage, Gene Expression, Genetic Predisposition to Disease, Genetic Variation, Genome, Human, Genome-Wide Association Study, Humans, Inhibitory Concentration 50, Neoplasms, Oligonucleotide Array Sequence Analysis, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Topoisomerase II Inhibitors
Added February 22, 2016
0 Communities
2 Members
0 Resources
22 MeSH Terms