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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 157

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Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins.
Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE
(2018) PLoS Pathog 14: e1006837
MeSH Terms: Amino Acid Sequence, Amino Acid Substitution, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antibody Specificity, Binding Sites, Antibody, Binding, Competitive, Cross Reactions, Epitope Mapping, Epitopes, Humans, Kinetics, Metapneumovirus, Microscopy, Electron, Mutation, Recombinant Proteins, Respiratory Syncytial Virus, Human, Viral Fusion Proteins
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.
Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE
(2017) J Biol Chem 292: 12165-12177
MeSH Terms: Animals, Binding, Competitive, Calcium Signaling, Cattle, Cell Line, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Humans, Lipid Bilayers, Liposomes, Membrane Fusion, Models, Molecular, Mutation, Nerve Tissue Proteins, Peptide Fragments, Protein Conformation, Protein Interaction Domains and Motifs, Protein Multimerization, Rats, Recombinant Fusion Proteins, Recombinant Proteins, Synaptosomal-Associated Protein 25, Synaptotagmin I, Syntaxin 1
Added July 12, 2017
0 Communities
2 Members
0 Resources
24 MeSH Terms
The pattern recognition reagents RAGE VC1 and peptide p5 share common binding sites and exhibit specific reactivity with AA amyloid in mice.
Kennel SJ, Williams A, Stuckey A, Richey T, Wooliver C, Chazin W, Stern DA, Martin EB, Wall JS
(2016) Amyloid 23: 8-16
MeSH Terms: Amyloidosis, Animals, Binding, Competitive, Iodine Radioisotopes, Mice, Inbred BALB C, Mice, Transgenic, Peptides, Protein Binding, Radiography, Dual-Energy Scanned Projection, Radiopharmaceuticals, Receptor for Advanced Glycation End Products, Recombinant Proteins, Serum Amyloid A Protein, Technetium, Tissue Distribution, Tomography, X-Ray Computed
Added March 11, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Competition and allostery govern substrate selectivity of cyclooxygenase-2.
Mitchener MM, Hermanson DJ, Shockley EM, Brown HA, Lindsley CW, Reese J, Rouzer CA, Lopez CF, Marnett LJ
(2015) Proc Natl Acad Sci U S A 112: 12366-71
MeSH Terms: Algorithms, Allosteric Regulation, Allosteric Site, Animals, Arachidonic Acid, Arachidonic Acids, Binding, Competitive, Catalytic Domain, Cell Line, Computer Simulation, Cyclooxygenase 2, Endocannabinoids, Glycerides, Kinetics, Macrophages, Mice, Oxidation-Reduction, Prostaglandins, Protein Binding, Protein Multimerization, Sf9 Cells, Spodoptera, Substrate Specificity, Zymosan
Added February 15, 2016
1 Communities
4 Members
0 Resources
24 MeSH Terms
Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11.
Kim D, Cha GS, Nagy LD, Yun CH, Guengerich FP
(2014) Biochemistry 53: 6161-72
MeSH Terms: Algorithms, Binding, Competitive, Biocatalysis, Cytochrome P-450 CYP4A, Cytochrome P-450 Enzyme System, Cytochromes b5, Deuterium, Electron Transport, Ferric Compounds, Ferrous Compounds, Humans, Hydroxylation, Kinetics, Lauric Acids, Models, Chemical, Models, Molecular, Oxidation-Reduction, Protein Binding, Protein Structure, Tertiary, Substrate Specificity, Tritium
Added January 20, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254).
Turlington M, Noetzel MJ, Chun A, Zhou Y, Gogliotti RD, Nguyen ED, Gregory KJ, Vinson PN, Rook JM, Gogi KK, Xiang Z, Bridges TM, Daniels JS, Jones C, Niswender CM, Meiler J, Conn PJ, Lindsley CW, Stauffer SR
(2013) J Med Chem 56: 7976-96
MeSH Terms: Acetylene, Allosteric Regulation, Amides, Animals, Binding, Competitive, Cell Membrane, Drug Discovery, Excitatory Postsynaptic Potentials, HEK293 Cells, Hippocampus, Humans, Male, Models, Chemical, Models, Molecular, Molecular Structure, Picolinic Acids, Protein Structure, Tertiary, Radioligand Assay, Rats, Rats, Sprague-Dawley, Receptor, Metabotropic Glutamate 5, Structure-Activity Relationship
Added January 24, 2015
1 Communities
4 Members
0 Resources
22 MeSH Terms
JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases.
Zhan X, Kaoud TS, Kook S, Dalby KN, Gurevich VV
(2013) J Biol Chem 288: 28535-47
MeSH Terms: Animals, Arrestins, Binding, Competitive, COS Cells, Chlorocebus aethiops, Humans, MAP Kinase Kinase 4, MAP Kinase Kinase 7, Mice, Mitogen-Activated Protein Kinase 10, Phosphorylation, Protein Binding, Substrate Specificity
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides.
Li F, Xia Y, Meiler J, Ferguson-Miller S
(2013) Biochemistry 52: 5884-99
MeSH Terms: Amino Acid Sequence, Apoptosis, Binding, Competitive, Carrier Proteins, Cholesterol, Cryoelectron Microscopy, Crystallization, Isoquinolines, Membrane Proteins, Mitochondrial Membranes, Protein Multimerization, Protoporphyrins, Receptors, GABA-A, Rhodobacter sphaeroides, Sequence Alignment
Added January 24, 2015
1 Communities
1 Members
0 Resources
15 MeSH Terms
Quantum dot approaches for target-based drug screening and multiplexed active biosensing.
Kovtun O, Arzeta-Ferrer X, Rosenthal SJ
(2013) Nanoscale 5: 12072-81
MeSH Terms: Animals, Binding, Competitive, Biosensing Techniques, Drug Evaluation, Preclinical, Endpoint Determination, Humans, Molecular Targeted Therapy, Quantum Dots, Surface Properties
Added May 27, 2014
0 Communities
2 Members
0 Resources
9 MeSH Terms
Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.
Klein MT, Vinson PN, Niswender CM
(2013) Prog Mol Biol Transl Sci 115: 1-59
MeSH Terms: Allosteric Regulation, Animals, Binding, Competitive, Biological Assay, Humans, Kinetics, Pharmaceutical Preparations, Receptors, Cell Surface
Added September 12, 2013
0 Communities
2 Members
0 Resources
8 MeSH Terms