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Results: 1 to 10 of 36

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Intestinal bile acids directly modulate the structure and function of TcdB toxin.
Tam J, Icho S, Utama E, Orrell KE, Gómez-Biagi RF, Theriot CM, Kroh HK, Rutherford SA, Lacy DB, Melnyk RA
(2020) Proc Natl Acad Sci U S A 117: 6792-6800
MeSH Terms: Bacterial Toxins, Bile Acids and Salts, Caco-2 Cells, Clostridioides difficile, Clostridium Infections, HCT116 Cells, Humans, Intestines, Receptors, Cell Surface
Added March 24, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Utilizing Untargeted Ion Mobility-Mass Spectrometry To Profile Changes in the Gut Metabolome Following Biliary Diversion Surgery.
Poland JC, Schrimpe-Rutledge AC, Sherrod SD, Flynn CR, McLean JA
(2019) Anal Chem 91: 14417-14423
MeSH Terms: Anastomosis, Surgical, Animals, Bile Acids and Salts, Bile Ducts, Cholesterol, Chromatography, Liquid, Duodenum, Fatty Acids, Volatile, Feces, Gastrointestinal Microbiome, Ileum, Jejunum, Male, Mass Spectrometry, Mice, Inbred C57BL
Added December 17, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery.
Flynn CR, Albaugh VL, Abumrad NN
(2019) Cell Mol Gastroenterol Hepatol 8: 235-246
MeSH Terms: Akkermansia, Animals, Bariatric Surgery, Bile Acids and Salts, Humans, Insulin Resistance, Obesity, Morbid, Receptors, Cytoplasmic and Nuclear, Signal Transduction, Verrucomicrobia
Added December 17, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Gastroesophageal Reflux Induces Protein Adducts in the Esophagus.
Caspa Gokulan R, Adcock JM, Zagol-Ikapitte I, Mernaugh R, Williams P, Washington KM, Boutaud O, Oates JA, Dikalov SI, Zaika AI
(2019) Cell Mol Gastroenterol Hepatol 7: 480-482.e7
MeSH Terms: Acetylcysteine, Animals, Benzylamines, Bile Acids and Salts, Cell Line, Cyclic N-Oxides, Esophagus, Gastroesophageal Reflux, Humans, Lipids, Mice, Spin Labels, Tumor Suppressor Protein p53
Added March 26, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Systemic bile acids induce insulin resistance in a TGR5-independent manner.
Syring KE, Cyphert TJ, Beck TC, Flynn CR, Mignemi NA, McGuinness OP
(2019) Am J Physiol Endocrinol Metab 316: E782-E793
MeSH Terms: Animals, Bile Acids and Salts, Cholagogues and Choleretics, Cholic Acids, Deoxycholic Acid, Gene Expression Profiling, Gluconeogenesis, Glucose Clamp Technique, Hep G2 Cells, Hepatocytes, Humans, Insulin Resistance, Liver, Mice, Mice, Knockout, Obesity, Primary Cell Culture, Receptors, G-Protein-Coupled, Taurocholic Acid
Added April 15, 2019
0 Communities
1 Members
0 Resources
19 MeSH Terms
Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery.
Albaugh VL, Banan B, Antoun J, Xiong Y, Guo Y, Ping J, Alikhan M, Clements BA, Abumrad NN, Flynn CR
(2019) Gastroenterology 156: 1041-1051.e4
MeSH Terms: Anastomosis, Surgical, Animals, Anticholesteremic Agents, Bariatric Surgery, Bile Acids and Salts, Blood Glucose, Cholestyramine Resin, Diet, High-Fat, Gallbladder, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Glucose Tolerance Test, Ileum, Insulin Resistance, Intestines, Lymph, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Signal Transduction, Verrucomicrobia, Weight Loss
Added January 4, 2019
0 Communities
2 Members
0 Resources
25 MeSH Terms
CD36 Modulates Fasting and Preabsorptive Hormone and Bile Acid Levels.
Shibao CA, Celedonio JE, Tamboli R, Sidani R, Love-Gregory L, Pietka T, Xiong Y, Wei Y, Abumrad NN, Abumrad NA, Flynn CR
(2018) J Clin Endocrinol Metab 103: 1856-1866
MeSH Terms: Adult, African Americans, Bile Acids and Salts, CD36 Antigens, Case-Control Studies, Energy Metabolism, Fasting, Female, Genotype, Hormones, Humans, Intestinal Absorption, Middle Aged, Polymorphism, Single Nucleotide
Added May 14, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Activation of NADPH oxidases leads to DNA damage in esophageal cells.
Bhardwaj V, Gokulan RC, Horvat A, Yermalitskaya L, Korolkova O, Washington KM, El-Rifai W, Dikalov SI, Zaika AI
(2017) Sci Rep 7: 9956
MeSH Terms: Barrett Esophagus, Bile Acids and Salts, Cells, Cultured, DNA Damage, Epithelial Cells, Humans, NADPH Oxidase 1, NADPH Oxidase 2, Reactive Oxygen Species
Added March 26, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
Bile acids and bariatric surgery.
Albaugh VL, Banan B, Ajouz H, Abumrad NN, Flynn CR
(2017) Mol Aspects Med 56: 75-89
MeSH Terms: Animals, Bile Acids and Salts, Diabetes Mellitus, Type 2, Enterohepatic Circulation, Gastrectomy, Gastric Bypass, Gastrointestinal Microbiome, Gene Expression Regulation, Glucose, Homeostasis, Humans, Insulin Resistance, Obesity, Morbid, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Rodentia, Signal Transduction
Added June 6, 2017
0 Communities
3 Members
0 Resources
17 MeSH Terms
Prevention of DNA damage in Barrett's esophageal cells exposed to acidic bile salts.
Bhardwaj V, Horvat A, Korolkova O, Washington MK, El-Rifai W, Dikalov SI, Zaika AI
(2016) Carcinogenesis 37: 1161-1169
MeSH Terms: Acetophenones, Acids, Adenocarcinoma, Antioxidants, BRCA1 Protein, Barrett Esophagus, Bile Acids and Salts, Cell Line, Tumor, DNA Damage, DNA Repair, Esophageal Neoplasms, Gastric Acid, Gastroesophageal Reflux, Humans, Reactive Oxygen Species
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms