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A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis.
Chao M, Wu H, Jin K, Li B, Wu J, Zhang G, Yang G, Hu X
(2016) Elife 5:
MeSH Terms: Acidosis, Lactic, Adult, Aged, Aged, 80 and over, Bicarbonates, Carcinoma, Chemoembolization, Therapeutic, Combined Modality Therapy, Female, Humans, Liver Neoplasms, Male, Middle Aged, Survival Analysis, Treatment Outcome
Added May 4, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Association of dialysate bicarbonate concentration with mortality in the Dialysis Outcomes and Practice Patterns Study (DOPPS).
Tentori F, Karaboyas A, Robinson BM, Morgenstern H, Zhang J, Sen A, Ikizler TA, Rayner H, Fissell RB, Vanholder R, Tomo T, Port FK
(2013) Am J Kidney Dis 62: 738-46
MeSH Terms: Aged, Bicarbonates, Cohort Studies, Dialysis Solutions, Female, Hospitalization, Humans, Male, Middle Aged, Outcome Assessment, Health Care, Prospective Studies, Renal Dialysis
Added August 21, 2013
0 Communities
2 Members
0 Resources
12 MeSH Terms
A two-hit mechanism for sepsis-induced impairment of renal tubule function.
Watts BA, George T, Sherwood ER, Good DW
(2013) Am J Physiol Renal Physiol 304: F863-74
MeSH Terms: Absorption, Aldosterone, Amiloride, Animals, Bicarbonates, Cecum, Extracellular Signal-Regulated MAP Kinases, Flavonoids, Kidney Tubules, Ligation, Lipopolysaccharides, Loop of Henle, Mice, Mice, Inbred C57BL, Sepsis, Toll-Like Receptor 4, Up-Regulation
Added October 18, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Basolateral LPS inhibits NHE3 and HCOFormula absorption through TLR4/MyD88-dependent ERK activation in medullary thick ascending limb.
Watts BA, George T, Sherwood ER, Good DW
(2011) Am J Physiol Cell Physiol 301: C1296-306
MeSH Terms: Absorption, Animals, Bicarbonates, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Humans, Kidney Tubules, Lipopolysaccharides, MAP Kinase Signaling System, Male, Mice, Myeloid Differentiation Factor 88, Rats, Rats, Sprague-Dawley, Renal Insufficiency, Sepsis, Sodium-Hydrogen Exchanger 3, Sodium-Hydrogen Exchangers, Toll-Like Receptor 4
Added October 18, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Sodium-bicarbonate cotransporter NBCn1 in the kidney medullary thick ascending limb cell line is upregulated under acidic conditions and enhances ammonium transport.
Lee S, Lee HJ, Yang HS, Thornell IM, Bevensee MO, Choi I
(2010) Exp Physiol 95: 926-37
MeSH Terms: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid, Ammonia, Animals, Anion Transport Proteins, Antiporters, Bicarbonates, Biological Transport, Cell Line, Chlorides, Gluconates, Hydrogen-Ion Concentration, Kidney Medulla, Kinetics, Loop of Henle, Membrane Potentials, Methylamines, Patch-Clamp Techniques, Quaternary Ammonium Compounds, Rats, SLC4A Proteins, Sodium, Sodium-Bicarbonate Symporters, Up-Regulation, Xenopus
Added March 14, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Dialysate ... Ho-hum!
Golper TA, Ward RA
(2009) Clin J Am Soc Nephrol 4: 1403-4
MeSH Terms: Acetic Acid, Anticoagulants, Bicarbonates, Biomarkers, Blood Coagulation, Blood Urea Nitrogen, Citric Acid, Creatinine, Dialysis Solutions, Humans, Kinetics, Phosphates, Renal Dialysis, Treatment Outcome, beta 2-Microglobulin
Added March 19, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Sample preparation and digestion for proteomic analyses using spin filters.
Manza LL, Stamer SL, Ham AJ, Codreanu SG, Liebler DC
(2005) Proteomics 5: 1742-5
MeSH Terms: Bicarbonates, Centrifugation, Mass Spectrometry, Peptides, Proteins, Proteomics, Trypsin
Added March 20, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease.
Eustace JA, Astor B, Muntner PM, Ikizler TA, Coresh J
(2004) Kidney Int 65: 1031-40
MeSH Terms: Acidosis, Adult, Aged, Bicarbonates, C-Reactive Protein, Female, Glomerular Filtration Rate, Humans, Hypoalbuminemia, Kidney Failure, Chronic, Male, Middle Aged, Prevalence, Risk Factors, Serum Albumin
Added September 29, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity.
Hink HU, Santanam N, Dikalov S, McCann L, Nguyen AD, Parthasarathy S, Harrison DG, Fukai T
(2002) Arterioscler Thromb Vasc Biol 22: 1402-8
MeSH Terms: Animals, Apolipoproteins E, Arteriosclerosis, Bicarbonates, Extracellular Space, Hydrogen Peroxide, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Peroxidase, Pichia, Recombinant Proteins, Spin Trapping, Substrate Specificity, Superoxide Dismutase, Superoxide Dismutase-1, Transfection, Uric Acid
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.
Moore KP, Holt SG, Patel RP, Svistunenko DA, Zackert W, Goodier D, Reeder BJ, Clozel M, Anand R, Cooper CE, Morrow JD, Wilson MT, Darley-Usmar V, Roberts LJ
(1998) J Biol Chem 273: 31731-7
MeSH Terms: Animals, Bicarbonates, Dinoprost, Disease Models, Animal, Electron Spin Resonance Spectroscopy, Glycerol, Humans, Hydrogen-Ion Concentration, Kidney, Lipoproteins, LDL, Metmyoglobin, Myoglobin, Oxidation-Reduction, Potassium Compounds, Rats, Renal Insufficiency, Rhabdomyolysis, Spectrophotometry, Vasoconstriction
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms