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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 5 of 5

Publication Record


Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Wang L, Cao H, Lu N, Liu L, Wang B, Hu T, Israel DA, Peek RM, Polk DB, Yan F
(2013) PLoS One 8: e56666
MeSH Terms: Animals, Antineoplastic Agents, Berberine, Cell Cycle Checkpoints, Cell Proliferation, Colonic Neoplasms, Down-Regulation, Enzyme Activation, ErbB Receptors, HT29 Cells, Humans, Mice, Mice, Inbred C57BL, Proto-Oncogene Proteins c-cbl, Xenograft Model Antitumor Assays
Added September 3, 2013
0 Communities
4 Members
0 Resources
15 MeSH Terms
Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor.
Wang L, Liu L, Shi Y, Cao H, Chaturvedi R, Calcutt MW, Hu T, Ren X, Wilson KT, Polk DB, Yan F
(2012) PLoS One 7: e36418
MeSH Terms: Active Transport, Cell Nucleus, Animals, Antineoplastic Agents, Apoptosis Inducing Factor, Berberine, Caspases, Cathepsin B, Cell Death, Cell Line, Tumor, Cell Nucleus, Colonic Neoplasms, Epithelial Cells, Humans, L-Lactate Dehydrogenase, Mice, Mitochondria, Poly(ADP-ribose) Polymerases, Reactive Oxygen Species
Added March 5, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice.
Yan F, Wang L, Shi Y, Cao H, Liu L, Washington MK, Chaturvedi R, Israel DA, Cao H, Wang B, Peek RM, Wilson KT, Polk DB
(2012) Am J Physiol Gastrointest Liver Physiol 302: G504-14
MeSH Terms: Animals, Apoptosis, Berberine, Colitis, Colon, Cytokines, Dextran Sulfate, Disease Models, Animal, Epithelial Cells, Inflammatory Bowel Diseases, Macrophages, Mice, Mice, Inbred C57BL, Tumor Necrosis Factor-alpha
Added September 3, 2013
0 Communities
7 Members
0 Resources
14 MeSH Terms
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.
Gomes AP, Duarte FV, Nunes P, Hubbard BP, Teodoro JS, Varela AT, Jones JG, Sinclair DA, Palmeira CM, Rolo AP
(2012) Biochim Biophys Acta 1822: 185-95
MeSH Terms: AMP-Activated Protein Kinases, Animals, Berberine, Cell Line, Diet, High-Fat, Glucose, Hormones, Hyperglycemia, Insulin Resistance, Male, Mice, Mitochondria, Mitochondria, Muscle, Muscle, Skeletal, Myoblasts, NAD, Obesity, Organelle Biogenesis, Phosphorylation, Rats, Rats, Sprague-Dawley, Sirtuin 1
Added April 25, 2013
0 Communities
0 Members
1 Resources
22 MeSH Terms
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study.
Affuso F, Ruvolo A, Micillo F, SaccĂ  L, Fazio S
(2010) Nutr Metab Cardiovasc Dis 20: 656-61
MeSH Terms: Anticholesteremic Agents, Berberine, Biological Products, Cholesterol, Cholesterol, LDL, Dietary Supplements, Double-Blind Method, Endothelium, Vascular, Fatty Alcohols, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypercholesterolemia, Insulin Resistance, Male, Middle Aged, Placebos, Triglycerides
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms